These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 36696764)

  • 1. Development of novel pyrazole, imidazo[1,2-b]pyrazole, and pyrazolo[1,5-a]pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory potential.
    Ayman R; Abusaif MS; Radwan AM; Elmetwally AM; Ragab A
    Eur J Med Chem; 2023 Mar; 249():115138. PubMed ID: 36696764
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel pyrazole and pyrazolo[1,5-a]pyrimidine derivatives as cyclooxygenase inhibitors (COX-1 and COX-2) using molecular modeling simulation.
    Ayman R; Radwan AM; Elmetwally AM; Ammar YA; Ragab A
    Arch Pharm (Weinheim); 2023 Feb; 356(2):e2200395. PubMed ID: 36336646
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE
    Labib MB; Fayez AM; El-Nahass ES; Awadallah M; Halim PA
    Bioorg Chem; 2020 Nov; 104():104308. PubMed ID: 33011534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies.
    Fadaly WAA; Elshaier YAMM; Hassanein EHM; Abdellatif KRA
    Bioorg Chem; 2020 May; 98():103752. PubMed ID: 32197148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages.
    Hamoud MMS; Osman NA; Rezq S; A A Abd El-Wahab H; E A Hassan A; Abdel-Fattah HA; Romero DG; Ghanim AM
    Bioorg Chem; 2022 Jul; 124():105808. PubMed ID: 35447409
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines.
    Abdelkhalek AS; Kothayer H; Rezq S; Orabi KY; Romero DG; El-Sabbagh OI
    Eur J Med Chem; 2023 Aug; 256():115443. PubMed ID: 37182334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core.
    Abdelall EKA; Lamie PF; Ahmed AKM; El-Nahass ES
    Bioorg Chem; 2019 May; 86():235-253. PubMed ID: 30716621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds.
    Atatreh N; Youssef AM; Ghattas MA; Al Sorkhy M; Alrawashdeh S; Al-Harbi KB; El-Ashmawy IM; Almundarij TI; Abdelghani AA; Abd-El-Aziz AS
    Bioorg Chem; 2019 May; 86():393-400. PubMed ID: 30763886
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase inhibitors with dual anti-inflammatory and anti-neoplastic activities.
    A A Fadaly W; A M M Elshaier Y; T M Nemr M; R A Abdellatif K
    Bioorg Chem; 2023 May; 134():106428. PubMed ID: 36893546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
    Amin NH; Hamed MIA; Abdel-Fattah MM; Abusabaa AHA; El-Saadi MT
    Bioorg Chem; 2021 Nov; 116():105394. PubMed ID: 34619468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aryl/heteroaryl Substituted Celecoxib Derivatives as COX-2 Inhibitors: Synthesis, Anti-inflammatory Activity and Molecular Docking Studies.
    Madhava G; Ramana KV; Sudhana SM; Rao DS; Kumar KH; Lokanatha V; Rani AU; Raju CN
    Med Chem; 2017; 13(5):484-497. PubMed ID: 28228088
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold.
    Bakr RB; Ghoneim AA; Azouz AA
    Bioorg Chem; 2019 Jul; 88():102964. PubMed ID: 31075742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2.
    Shaker AMM; Shahin MI; AboulMagd AM; Abdel Aleem SA; Abdel-Rahman HM; Abou El Ella DA
    Bioorg Chem; 2022 Dec; 129():106143. PubMed ID: 36191430
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
    Abdelall EKA; Lamie PF; Ali WAM
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2893-2899. PubMed ID: 27158139
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel pyrimidines as COX-2 selective inhibitors: synthesis, DFT analysis, molecular docking and dynamic simulation studies.
    Mathada BS; Basha NJ; Javeed M; Karunakar P; Venkatesulu A; Erappa K; Varsha A
    J Biomol Struct Dyn; 2024; 42(4):1751-1764. PubMed ID: 37102863
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.
    Alfayomy AM; Abdel-Aziz SA; Marzouk AA; Shaykoon MSA; Narumi A; Konno H; Abou-Seri SM; Ragab FAF
    Bioorg Chem; 2021 Mar; 108():104555. PubMed ID: 33376011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, Characterization, Antimicrobial Activity and Anticancer of Some New Pyrazolo[1,5-a]pyrimidines and Pyrazolo[5,1-c]1,2,4-triazines.
    Hosny MA; Zaki YH; Mokbel WA; Abdelhamid AO
    Med Chem; 2020; 16(6):750-760. PubMed ID: 31218963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies.
    Abdellatif KRA; Abdelall EKA; Elshemy HAH; Philoppes JN; Hassanein EHM; Kahk NM
    Bioorg Chem; 2021 Sep; 114():105122. PubMed ID: 34243075
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile.
    Abdellatif KRA; Fadaly WAA; Elshaier YAMM; Ali WAM; Kamel GM
    Bioorg Chem; 2018 Apr; 77():568-578. PubMed ID: 29475165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors.
    Abdellatif KRA; Fadaly WAA; Kamel GM; Elshaier YAMM; El-Magd MA
    Bioorg Chem; 2019 Feb; 82():86-99. PubMed ID: 30278282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.