119 related articles for article (PubMed ID: 36711727)
1. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.
Malgulwar PB; Danussi C; Dharmaiah S; Johnson WE; Rao A; Huse JT
bioRxiv; 2023 Jan; ():. PubMed ID: 36711727
[TBL] [Abstract][Full Text] [Related]
2. Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.
Malgulwar PB; Danussi C; Dharmaiah S; Johnson W; Singh A; Rai K; Rao A; Huse JT
Neuro Oncol; 2024 Jan; 26(1):55-67. PubMed ID: 37625115
[TBL] [Abstract][Full Text] [Related]
3. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.
Danussi C; Bose P; Parthasarathy PT; Silberman PC; Van Arnam JS; Vitucci M; Tang OY; Heguy A; Wang Y; Chan TA; Riggins GJ; Sulman EP; Lang FF; Creighton CJ; Deneen B; Miller CR; Picketts DJ; Kannan K; Huse JT
Nat Commun; 2018 Mar; 9(1):1057. PubMed ID: 29535300
[TBL] [Abstract][Full Text] [Related]
4. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma.
Kannan K; Inagaki A; Silber J; Gorovets D; Zhang J; Kastenhuber ER; Heguy A; Petrini JH; Chan TA; Huse JT
Oncotarget; 2012 Oct; 3(10):1194-203. PubMed ID: 23104868
[TBL] [Abstract][Full Text] [Related]
5. Omics-based integrated analysis identified ATRX as a biomarker associated with glioma diagnosis and prognosis.
Xie Y; Tan Y; Yang C; Zhang X; Xu C; Qiao X; Xu J; Tian S; Fang C; Kang C
Cancer Biol Med; 2019 Nov; 16(4):784-796. PubMed ID: 31908895
[TBL] [Abstract][Full Text] [Related]
6. Novel insights into the epigenetics of diffuse glioma.
Danussi C; Huse JT
Mol Cell Oncol; 2018; 5(5):e1472055. PubMed ID: 30263940
[TBL] [Abstract][Full Text] [Related]
7. ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors.
Pladevall-Morera D; Castejón-Griñán M; Aguilera P; Gaardahl K; Ingham A; Brosnan-Cashman JA; Meeker AK; Lopez-Contreras AJ
Cancers (Basel); 2022 Mar; 14(7):. PubMed ID: 35406561
[TBL] [Abstract][Full Text] [Related]
8. Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.
Bedics G; Szőke P; Bátai B; Nagy T; Papp G; Kránitz N; Rajnai H; Reiniger L; Bödör C; Scheich B
Sci Rep; 2023 Oct; 13(1):18436. PubMed ID: 37891325
[TBL] [Abstract][Full Text] [Related]
9. SIRT2 inhibition as the Achilles' heel of ATRX-deficient gliomas.
Turcan Ş
Neuro Oncol; 2024 Jan; 26(1):68-69. PubMed ID: 37941518
[No Abstract] [Full Text] [Related]
10. Global changes in chromatin accessibility and transcription following ATRX inactivation in human cancer cells.
Liang J; Liu H; Li G; Qian J; Gao R; Zhou Y; Wang X
FEBS Lett; 2020 Jan; 594(1):67-78. PubMed ID: 31329278
[TBL] [Abstract][Full Text] [Related]
11. Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma.
Mukherjee J; Johannessen TC; Ohba S; Chow TT; Jones L; Pandita A; Pieper RO
Cancer Res; 2018 Jun; 78(11):2966-2977. PubMed ID: 29545335
[TBL] [Abstract][Full Text] [Related]
12. ATRX loss promotes immunosuppressive mechanisms in IDH1 mutant glioma.
Hu C; Wang K; Damon C; Fu Y; Ma T; Kratz L; Lal B; Ying M; Xia S; Cahill DP; Jackson CM; Lim M; Laterra J; Li Y
Neuro Oncol; 2022 Jun; 24(6):888-900. PubMed ID: 34951647
[TBL] [Abstract][Full Text] [Related]
13. Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.
Palomer E; Martín-Flores N; Jolly S; Pascual-Vargas P; Benvegnù S; Podpolny M; Teo S; Vaher K; Saito T; Saido TC; Whiting P; Salinas PC
Mol Psychiatry; 2022 Jul; 27(7):3024-3033. PubMed ID: 35296808
[TBL] [Abstract][Full Text] [Related]
14. Monoallelic IDH1 R132H Mutation Mediates Glioma Cell Response to Anticancer Therapies via Induction of Senescence.
Zhan D; Ma D; Wei S; Lal B; Fu Y; Eberhart C; Laterra J; Ying M; Li Y; Meeker A; Lopez-Bertoni H; Xia S
Mol Cancer Res; 2021 Nov; 19(11):1878-1888. PubMed ID: 34348994
[TBL] [Abstract][Full Text] [Related]
15. G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma.
Wang Y; Yang J; Wild AT; Wu WH; Shah R; Danussi C; Riggins GJ; Kannan K; Sulman EP; Chan TA; Huse JT
Nat Commun; 2019 Feb; 10(1):943. PubMed ID: 30808951
[TBL] [Abstract][Full Text] [Related]
16. MicroRNA-1269a Promotes Proliferation and Arrest of Apoptosis of Glioma Cells by Directly Targeting ATRX.
Zhang Y; Wang Q; Luo N; Liu J; Ren H; Shao X; Zhang L; Yu Y
Front Oncol; 2020; 10():563901. PubMed ID: 33194637
[TBL] [Abstract][Full Text] [Related]
17. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma.
Han B; Meng X; Wu P; Li Z; Li S; Zhang Y; Zha C; Ye Q; Jiang C; Cai J; Jiang T
Theranostics; 2020; 10(7):3351-3365. PubMed ID: 32194873
[No Abstract] [Full Text] [Related]
18. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Núñez FJ; Mendez FM; Kadiyala P; Alghamri MS; Savelieff MG; Garcia-Fabiani MB; Haase S; Koschmann C; Calinescu AA; Kamran N; Saxena M; Patel R; Carney S; Guo MZ; Edwards M; Ljungman M; Qin T; Sartor MA; Tagett R; Venneti S; Brosnan-Cashman J; Meeker A; Gorbunova V; Zhao L; Kremer DM; Zhang L; Lyssiotis CA; Jones L; Herting CJ; Ross JL; Hambardzumyan D; Hervey-Jumper S; Figueroa ME; Lowenstein PR; Castro MG
Sci Transl Med; 2019 Feb; 11(479):. PubMed ID: 30760578
[TBL] [Abstract][Full Text] [Related]
19. Mutant ATRX: uncovering a new therapeutic target for glioma.
Haase S; Garcia-Fabiani MB; Carney S; Altshuler D; Núñez FJ; Méndez FM; Núñez F; Lowenstein PR; Castro MG
Expert Opin Ther Targets; 2018 Jul; 22(7):599-613. PubMed ID: 29889582
[TBL] [Abstract][Full Text] [Related]
20. SIRT2 activity is required for the survival of C6 glioma cells.
He X; Nie H; Hong Y; Sheng C; Xia W; Ying W
Biochem Biophys Res Commun; 2012 Jan; 417(1):468-72. PubMed ID: 22166219
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
