BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 36724966)

  • 1. Chronic Treatment with Aβ42 with a Toxic Conformer and LPS Induces Inflammatory Responses in BV-2 Microglia with Dysregulation of Hypoxia-Inducible Factor Expression.
    Maki T; Sawahata M; Uta D; Irie K; Kume T
    Biol Pharm Bull; 2023; 46(2):359-363. PubMed ID: 36724966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APP Knock-In Mice Produce E22P-Aβ Exhibiting an Alzheimer's Disease-like Phenotype with Dysregulation of Hypoxia-Inducible Factor Expression.
    Maki T; Sawahata M; Akutsu I; Amaike S; Hiramatsu G; Uta D; Izuo N; Shimizu T; Irie K; Kume T
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36362046
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
    Imamura T; Yanagihara YT; Ohyagi Y; Nakamura N; Iinuma KM; Yamasaki R; Asai H; Maeda M; Murakami K; Irie K; Kira JI
    Neurobiol Dis; 2020 Apr; 137():104739. PubMed ID: 31927145
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An RNA aptamer with potent affinity for a toxic dimer of amyloid β42 has potential utility for histochemical studies of Alzheimer's disease.
    Murakami K; Obata Y; Sekikawa A; Ueda H; Izuo N; Awano T; Takabe K; Shimizu T; Irie K
    J Biol Chem; 2020 Apr; 295(15):4870-4880. PubMed ID: 32127399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential regulation of HIF-3α in LPS-induced BV-2 microglial cells: Comparison and characterization with HIF-1α.
    Kumar H; Lim JH; Kim IS; Choi DK
    Brain Res; 2015 Jun; 1610():33-41. PubMed ID: 25847716
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.
    Izuo N; Kume T; Sato M; Murakami K; Irie K; Izumi Y; Akaike A
    ACS Chem Neurosci; 2012 Sep; 3(9):674-81. PubMed ID: 23019494
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain.
    Kageyama Y; Irie Y; Matsushima Y; Segawa T; Bellier JP; Hidaka K; Sugiyama H; Kaneda D; Hashizume Y; Akatsu H; Miki K; Kita A; Walker DG; Irie K; Tooyama I
    ACS Chem Neurosci; 2021 Sep; 12(18):3418-3432. PubMed ID: 34464082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage.
    Ferrera D; Mazzaro N; Canale C; Gasparini L
    Neurobiol Aging; 2014 Nov; 35(11):2444-2457. PubMed ID: 24973120
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis of the 24B3 antibody against the toxic conformer of amyloid β with a turn at positions 22 and 23.
    Irie Y; Matsushima Y; Kita A; Miki K; Segawa T; Maeda M; Yanagita RC; Irie K
    Biochem Biophys Res Commun; 2022 Sep; 621():162-167. PubMed ID: 35839743
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-amyloid binds to microglia Dectin-1 to induce inflammatory response in the pathogenesis of Alzheimer's disease.
    Zhao X; Sun J; Xiong L; She L; Li L; Tang H; Zeng Y; Chen F; Han X; Ye S; Wang W; Wang X; Liang G
    Int J Biol Sci; 2023; 19(10):3249-3265. PubMed ID: 37416769
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low-Dose Ionizing Radiation Modulates Microglia Phenotypes in the Models of Alzheimer's Disease.
    Kim S; Chung H; Ngoc Mai H; Nam Y; Shin SJ; Park YH; Chung MJ; Lee JK; Rhee HY; Jahng GH; Kim Y; Lim YJ; Kong M; Moon M; Chung WK
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32630597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells.
    Lee YJ; Choi DY; Choi IS; Han JY; Jeong HS; Han SB; Oh KW; Hong JT
    J Neuroinflammation; 2011 Oct; 8():132. PubMed ID: 21982455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Andrographolide attenuates microglia-mediated Aβ neurotoxicity partially through inhibiting NF-κB and JNK MAPK signaling pathway.
    Yang R; Liu S; Zhou J; Bu S; Zhang J
    Immunopharmacol Immunotoxicol; 2017 Oct; 39(5):276-284. PubMed ID: 28669260
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GSK3β is involved in promoting Alzheimer's disease pathologies following chronic systemic exposure to Porphyromonas gingivalis lipopolysaccharide in amyloid precursor protein
    Jiang M; Zhang X; Yan X; Mizutani S; Kashiwazaki H; Ni J; Wu Z
    Brain Behav Immun; 2021 Nov; 98():1-12. PubMed ID: 34391814
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An App knock-in mouse inducing the formation of a toxic conformer of Aβ as a model for evaluating only oligomer-induced cognitive decline in Alzheimer's disease.
    Izuo N; Murakami K; Fujihara Y; Maeda M; Saito T; Saido TC; Irie K; Shimizu T
    Biochem Biophys Res Commun; 2019 Jul; 515(3):462-467. PubMed ID: 31164199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Hypoxia Inducible Factor-1α in Alzheimer's Disease.
    Wang YY; Huang ZT; Yuan MH; Jing F; Cai RL; Zou Q; Pu YS; Wang SY; Chen F; Yi WM; Zhang HJ; Cai ZY
    J Alzheimers Dis; 2021; 80(3):949-961. PubMed ID: 33612545
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bis(ethylmaltolato)oxidovanadium (IV) attenuates amyloid-beta-mediated neuroinflammation by inhibiting NF-κB signaling pathway via a PPARγ-dependent mechanism.
    He Z; Li X; Han S; Ren B; Hu X; Li N; Du X; Ni J; Yang X; Liu Q
    Metallomics; 2021 Jul; 13(7):. PubMed ID: 34124763
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice.
    Knopp RC; Baumann KK; Wilson ML; Banks WA; Erickson MA
    Int J Mol Sci; 2022 Feb; 23(4):. PubMed ID: 35216491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Development of a Novel Alzheimer's Disease Model Based on the Theory of the Toxic-conformer of Amyloid β].
    Izuo N; Shimizu T; Murakami K; Irie K
    Yakugaku Zasshi; 2021; 141(6):843-849. PubMed ID: 34078792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model.
    Hoeijmakers L; Ruigrok SR; Amelianchik A; Ivan D; van Dam AM; Lucassen PJ; Korosi A
    Brain Behav Immun; 2017 Jul; 63():160-175. PubMed ID: 28027926
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.