172 related articles for article (PubMed ID: 36730356)
1. Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel.
Wei M; Wang P; Zhu X; Morishima M; Liu Y; Zheng M; Liu G; Osanai H; Yoshimura K; Kume S; Kurokawa T; Ono K
PLoS One; 2023; 18(2):e0280656. PubMed ID: 36730356
[TBL] [Abstract][Full Text] [Related]
2. Electrophysiological characterization of the modified hERG
Zhang Y; Dempsey CE; Hancox JC
Physiol Rep; 2020 Oct; 8(20):e14568. PubMed ID: 33091232
[TBL] [Abstract][Full Text] [Related]
3. The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.
Hisajima N; Hata Y; Kinoshita K; Fukushima T; Nishida N; Kano M; Tabata T
Biol Pharm Bull; 2015; 38(5):781-4. PubMed ID: 25947924
[TBL] [Abstract][Full Text] [Related]
4. The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (I
Teah YF; Abduraman MA; Amanah A; Adenan MI; Sulaiman SF; Tan ML
Food Chem Toxicol; 2017 Sep; 107(Pt A):293-301. PubMed ID: 28689918
[TBL] [Abstract][Full Text] [Related]
5. Anti-Ro52 antibody acts on the S5-pore linker of hERG to chronically reduce channel expression.
Szendrey J; Lamothe SM; Vanner S; Guo J; Yang T; Li W; Davis J; Joneja M; Baranchuk A; Zhang S
Cardiovasc Res; 2019 Aug; 115(10):1500-1511. PubMed ID: 30544220
[TBL] [Abstract][Full Text] [Related]
6. Serine mutation of a conserved threonine in the hERG K
Al-Moubarak E; Zhang Y; Dempsey CE; Zhang H; Harmer SC; Hancox JC
Biochem Biophys Res Commun; 2020 Jun; 526(4):1085-1091. PubMed ID: 32321643
[TBL] [Abstract][Full Text] [Related]
7. State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy.
Ganapathi SB; Kester M; Elmslie KS
Am J Physiol Cell Physiol; 2009 Apr; 296(4):C701-10. PubMed ID: 19244476
[TBL] [Abstract][Full Text] [Related]
8. Clemastine, a conventional antihistamine, is a high potency inhibitor of the HERG K+ channel.
Ridley JM; Milnes JT; Hancox JC; Witchel HJ
J Mol Cell Cardiol; 2006 Jan; 40(1):107-18. PubMed ID: 16288909
[TBL] [Abstract][Full Text] [Related]
9. Tbx20 controls the expression of the KCNH2 gene and of hERG channels.
Caballero R; Utrilla RG; Amorós I; Matamoros M; Pérez-Hernández M; Tinaquero D; Alfayate S; Nieto-Marín P; Guerrero-Serna G; Liu QH; Ramos-Mondragón R; Ponce-Balbuena D; Herron T; Campbell KF; Filgueiras-Rama D; Peinado R; López-Sendón JL; Jalife J; Delpón E; Tamargo J
Proc Natl Acad Sci U S A; 2017 Jan; 114(3):E416-E425. PubMed ID: 28049825
[TBL] [Abstract][Full Text] [Related]
10. Altered gating of HERG potassium channels by cobalt and lanthanum.
Sanchez-Chapula JA; Sanguinetti MC
Pflugers Arch; 2000 Jun; 440(2):264-74. PubMed ID: 10898527
[TBL] [Abstract][Full Text] [Related]
11. Differential Regulation of Human Ether-à-Go-Go-Related Gene (hERG) Current and Expression by Activation of Protein Kinase C.
Sutherland-Deveen ME; Wang T; Lamothe SM; Tschirhart JN; Guo J; Li W; Yang T; Du Y; Zhang S
Mol Pharmacol; 2019 Jul; 96(1):1-12. PubMed ID: 31015282
[TBL] [Abstract][Full Text] [Related]
12. Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b.
Tschirhart JN; Zhang S
Mol Pharmacol; 2020 Oct; 98(4):508-517. PubMed ID: 32321735
[TBL] [Abstract][Full Text] [Related]
13. Hydroxychloroquine Attenuates hERG Channel by Promoting the Membrane Channel Degradation: Computational Simulation and Experimental Evidence for QT-Interval Prolongation with Hydroxychloroquine Treatment.
Wang X; Feng Y; Liu S; Liu J; Pan S; Wei L; Ma Y; Liu Z; Xing Y; Wang J; Cui Q; Zhang Y; Wang T; Cai C
Cardiology; 2023; 148(4):310-323. PubMed ID: 37231805
[TBL] [Abstract][Full Text] [Related]
14. Action potential clamp characterization of the S631A hERG mutation associated with short QT syndrome.
Butler A; Zhang Y; Stuart AG; Dempsey CE; Hancox JC
Physiol Rep; 2018 Sep; 6(17):e13845. PubMed ID: 30175559
[TBL] [Abstract][Full Text] [Related]
15. A novel missense mutation causing a G487R substitution in the S2-S3 loop of human ether-à-go-go-related gene channel.
Kinoshita K; Yamaguchi Y; Nishide K; Kimoto K; Nonobe Y; Fujita A; Asano K; Tabata T; Mori H; Inoue H; Hata Y; Fukurotani K; Nishida N
J Cardiovasc Electrophysiol; 2012 Nov; 23(11):1246-53. PubMed ID: 22764740
[TBL] [Abstract][Full Text] [Related]
16. Cyclovirobuxine D inhibits the currents of HERG potassium channels stably expressed in HEK293 cells.
Zhao J; Wang Q; Xu J; Zhao J; Liu G; Peng S
Eur J Pharmacol; 2011 Jun; 660(2-3):259-67. PubMed ID: 21497594
[TBL] [Abstract][Full Text] [Related]
17. Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias.
Potet F; Lorinc AN; Chaigne S; Hopkins CR; Venkataraman R; Stepanovic SZ; Lewis LM; Days E; Sidorov VY; Engers DW; Zou B; Afshartous D; George AL; Campbell CM; Balser JR; Li M; Baudenbacher FJ; Lindsley CW; Weaver CD; Kupershmidt S
J Biol Chem; 2012 Nov; 287(47):39613-25. PubMed ID: 23033485
[TBL] [Abstract][Full Text] [Related]
18. Modulation of HERG K+ channels by chronic exposure to activators and inhibitors of PKA and PKC: actions independent of PKA and PKC phosphorylation.
Shu L; Zhang W; Su G; Zhang J; Liu C; Xu J
Cell Physiol Biochem; 2013; 32(6):1830-44. PubMed ID: 24356123
[TBL] [Abstract][Full Text] [Related]
19. Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutants.
Du C; Zhang Y; El Harchi A; Dempsey CE; Hancox JC
J Mol Cell Cardiol; 2014 Sep; 74(100):220-30. PubMed ID: 24877995
[TBL] [Abstract][Full Text] [Related]
20. Downregulation of hERG channel expression by tyrosine kinase inhibitors nilotinib and vandetanib predominantly contributes to arrhythmogenesis.
Cui X; Sun J; Li C; Qiu S; Shi C; Ma J; Xu Y
Toxicol Lett; 2022 Jul; 365():11-23. PubMed ID: 35680041
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]