BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 36730444)

  • 1. Success of Trametinib in the Treatment of Langerhans Cell Histiocytosis With Novel MAPK Pathway Mutations.
    Orr K; Hustak S; Beaudoin R; Ray A
    J Pediatr Hematol Oncol; 2023 May; 45(4):e534-e538. PubMed ID: 36730444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Langerhans cell histiocytosis with BRAF p.N486_P490del or MAP2K1 p.K57_G61del treated by the MEK inhibitor trametinib.
    Messinger YH; Bostrom BC; Olson DR; Gossai NP; Miller LH; Richards MK
    Pediatr Blood Cancer; 2020 Dec; 67(12):e28712. PubMed ID: 32991018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic ARAF mutations in pediatric Langerhans cell histiocytosis: clinicopathologic, genetic and functional profiling.
    Liu R; Guo Y; Han L; Feng S; Cao J; Sun Y; Cao Z; Cui X
    Clin Exp Med; 2023 Dec; 23(8):5269-5279. PubMed ID: 37572153
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical and prognostic characteristics of 95 cases of Langerhans cell histiocytosis in children: a single-institute experience from 2013 to 2020.
    Tang X; Gao J; Ma ZG; Guo X; Li Q; Wan Z; Sun JJ
    Ann Med; 2021 Dec; 53(1):1537-1546. PubMed ID: 34459688
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MAPK/ERK signal pathway alterations in patients with Langerhans Cell Histiocytosis.
    Novosad O; Skrypets T; Pastushenko Y; Titorenko I; Martynchyk A; Skachkova O; Inomistova M; Gorbach A; Khranovska N; Kryachok I
    Klin Onkol; 2018; 31(2):130-136. PubMed ID: 29708356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clinical resistance associated with a novel MAP2K1 mutation in a patient with Langerhans cell histiocytosis.
    Azorsa DO; Lee DW; Wai DH; Bista R; Patel AR; Aleem E; Henry MM; Arceci RJ
    Pediatr Blood Cancer; 2018 Sep; 65(9):e27237. PubMed ID: 29768711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical implications of oncogenic mutations in pulmonary Langerhans cell histiocytosis.
    Brown NA; Elenitoba-Johnson KSJ
    Curr Opin Pulm Med; 2018 May; 24(3):281-286. PubMed ID: 29470255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Langerhans cell histiocytosis: A neoplastic disorder driven by Ras-ERK pathway mutations.
    Tran G; Huynh TN; Paller AS
    J Am Acad Dermatol; 2018 Mar; 78(3):579-590.e4. PubMed ID: 29107340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis.
    Gao XM; Li J; Cao XX
    Cell Commun Signal; 2022 Dec; 20(1):195. PubMed ID: 36536400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Langerhans cell histiocytosis: current advances in molecular pathogenesis.
    Sconocchia T; Foßelteder J; Sconocchia G; Reinisch A
    Front Immunol; 2023; 14():1275085. PubMed ID: 37965340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Advances in our understanding of genetic markers and targeted therapies for pediatric LCH.
    Bahabri A; Abla O
    Expert Rev Hematol; 2024 Jun; 17(6):223-231. PubMed ID: 38721670
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.
    Chakraborty R; Hampton OA; Shen X; Simko SJ; Shih A; Abhyankar H; Lim KP; Covington KR; Trevino L; Dewal N; Muzny DM; Doddapaneni H; Hu J; Wang L; Lupo PJ; Hicks MJ; Bonilla DL; Dwyer KC; Berres ML; Poulikakos PI; Merad M; McClain KL; Wheeler DA; Allen CE; Parsons DW
    Blood; 2014 Nov; 124(19):3007-15. PubMed ID: 25202140
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Langerhans cell histiocytosis is a neoplasm and consequently its recurrence is a relapse: In memory of Bob Arceci.
    Egeler RM; Katewa S; Leenen PJ; Beverley P; Collin M; Ginhoux F; Arceci RJ; Rollins BJ;
    Pediatr Blood Cancer; 2016 Oct; 63(10):1704-12. PubMed ID: 27314817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BRAFV600E and MAP2K1 mutations in Langerhans cell histiocytosis occur predominantly in children.
    Zeng K; Ohshima K; Liu Y; Zhang W; Wang L; Fan L; Li M; Li X; Wang Z; Guo S; Yan Q; Guo Y
    Hematol Oncol; 2017 Dec; 35(4):845-851. PubMed ID: 27597420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitogen-activating protein kinase pathway alterations in Langerhans cell histiocytosis.
    Jouenne F; Benattia A; Tazi A
    Curr Opin Oncol; 2021 Mar; 33(2):101-109. PubMed ID: 33315630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of the BRAF and MAP2K1 mutations in patients with Langerhans cell histiocytosis in Japan.
    Hayase T; Saito S; Shioda Y; Imamura T; Watanabe K; Ohki K; Yoshioka T; Oh Y; Kawahara Y; Niijima H; Imashuku S; Morimoto A
    Int J Hematol; 2020 Oct; 112(4):560-567. PubMed ID: 32654047
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New somatic BRAF splicing mutation in Langerhans cell histiocytosis.
    Héritier S; Hélias-Rodzewicz Z; Chakraborty R; Sengal AG; Bellanné-Chantelot C; Thomas C; Moreau A; Fraitag S; Allen CE; Donadieu J; Emile JF
    Mol Cancer; 2017 Jul; 16(1):115. PubMed ID: 28679432
    [TBL] [Abstract][Full Text] [Related]  

  • 18. B-RAF mutant alleles associated with Langerhans cell histiocytosis, a granulomatous pediatric disease.
    Satoh T; Smith A; Sarde A; Lu HC; Mian S; Trouillet C; Mufti G; Emile JF; Fraternali F; Donadieu J; Geissmann F
    PLoS One; 2012; 7(4):e33891. PubMed ID: 22506009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recurrent NRAS mutations in pulmonary Langerhans cell histiocytosis.
    Mourah S; How-Kit A; Meignin V; Gossot D; Lorillon G; Bugnet E; Mauger F; Lebbe C; Chevret S; Tost J; Tazi A
    Eur Respir J; 2016 Jun; 47(6):1785-96. PubMed ID: 27076591
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis.
    Zarnegar S; Durham BH; Khattar P; Shukla NN; Benayed R; Lacouture ME; Lavi E; Lyden DC; Diamond EL; Dunkel IJ; Abdel-Wahab O
    Pediatr Blood Cancer; 2018 Jan; 65(1):. PubMed ID: 28748614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.