These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 36736525)

  • 1. Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139.
    Pallareti L; Rath TF; Trapkov B; Tsonkov T; Nielsen AT; Harpsøe K; Gentry PR; Bräuner-Osborne H; Gloriam DE; Foster SR
    Eur J Pharmacol; 2023 Mar; 943():175553. PubMed ID: 36736525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a novel scaffold for a small molecule GPR139 receptor agonist.
    Nøhr AC; Shehata MA; Palmer D; Pokhrel R; Vallianou M; Foster SR; Gentry PR; Gloriam DE; Bräuner-Osborne H
    Sci Rep; 2019 Mar; 9(1):3802. PubMed ID: 30846711
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of surrogate agonists and antagonists for orphan G-protein-coupled receptor GPR139.
    Hu LA; Tang PM; Eslahi NK; Zhou T; Barbosa J; Liu Q
    J Biomol Screen; 2009 Aug; 14(7):789-97. PubMed ID: 19525486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GPR139, an Orphan Receptor Highly Enriched in the Habenula and Septum, Is Activated by the Essential Amino Acids L-Tryptophan and L-Phenylalanine.
    Liu C; Bonaventure P; Lee G; Nepomuceno D; Kuei C; Wu J; Li Q; Joseph V; Sutton SW; Eckert W; Yao X; Yieh L; Dvorak C; Carruthers N; Coate H; Yun S; Dugovic C; Harrington A; Lovenberg TW
    Mol Pharmacol; 2015 Nov; 88(5):911-25. PubMed ID: 26349500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139
    Nepomuceno D; Kuei C; Dvorak C; Lovenberg T; Liu C; Bonaventure P
    Front Pharmacol; 2018; 9():157. PubMed ID: 29599718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
    Nøhr AC; Shehata MA; Hauser AS; Isberg V; Mokrosinski J; Andersen KB; Farooqi IS; Pedersen DS; Gloriam DE; Bräuner-Osborne H
    Neurochem Int; 2017 Jan; 102():105-113. PubMed ID: 27916541
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139.
    Shi F; Shen JK; Chen D; Fog K; Thirstrup K; Hentzer M; Karlsson JJ; Menon V; Jones KA; Smith KE; Smith G
    ACS Med Chem Lett; 2011 Apr; 2(4):303-6. PubMed ID: 24900311
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats.
    Kononoff J; Kallupi M; Kimbrough A; Conlisk D; de Guglielmo G; George O
    eNeuro; 2018; 5(3):. PubMed ID: 29971251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia.
    Reichard HA; Schiffer HH; Monenschein H; Atienza JM; Corbett G; Skaggs AW; Collia DR; Ray WJ; Serrats J; Bliesath J; Kaushal N; Lam BP; Amador-Arjona A; Rahbaek L; McConn DJ; Mulligan VJ; Brice N; Gaskin PLR; Cilia J; Hitchcock S
    J Med Chem; 2021 Aug; 64(15):11527-11542. PubMed ID: 34260228
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology.
    Kaushik AC; Gautam D; Nangraj AS; Wei DQ; Sahi S
    Interdiscip Sci; 2019 Jun; 11(2):247-257. PubMed ID: 31177377
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site.
    Nøhr AC; Jespers W; Shehata MA; Floryan L; Isberg V; Andersen KB; Åqvist J; Gutiérrez-de-Terán H; Bräuner-Osborne H; Gloriam DE
    Sci Rep; 2017 Apr; 7(1):1128. PubMed ID: 28442765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of orphan receptor GPR139 in neuropsychiatric behavior.
    Dao M; Stoveken HM; Cao Y; Martemyanov KA
    Neuropsychopharmacology; 2022 Mar; 47(4):902-913. PubMed ID: 33479510
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-throughput screening of antagonists for the orphan G-protein coupled receptor GPR139.
    Wang J; Zhu LY; Liu Q; Hentzer M; Smith GP; Wang MW
    Acta Pharmacol Sin; 2015 Jul; 36(7):874-8. PubMed ID: 26027661
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The orphan receptor GPR139 signals via G
    Stoveken HM; Zucca S; Masuho I; Grill B; Martemyanov KA
    J Biol Chem; 2020 Jul; 295(31):10822-10830. PubMed ID: 32576659
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutagenesis of GPR139 reveals ways to create gain or loss of function receptors.
    Wang L; Lee G; Shih A; Kuei C; Nepomuceno D; Wennerholm M; Fan F; Wu J; Bonaventure P; Lovenberg TW; Liu C
    Pharmacol Res Perspect; 2019 Feb; 7(1):e00466. PubMed ID: 30774960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The orphan G protein-coupled receptor, GPR139, is expressed in the hypothalamus and is involved in the regulation of body mass, blood glucose, and insulin.
    Nogueira PAS; Moura-Assis A; Zanesco AM; Bombassaro B; Gallo-Ferraz AL; Simões MR; Engel DF; Razolli DS; Gaspar JM; Junior JD; Velloso LA
    Neurosci Lett; 2023 Jan; 792():136955. PubMed ID: 36347339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact.
    Wang L; Lee G; Kuei C; Yao X; Harrington A; Bonaventure P; Lovenberg TW; Liu C
    Front Neurosci; 2019; 13():281. PubMed ID: 30971885
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Habenula GPR139 is associated with fear learning in the zebrafish.
    Roy N; Ogawa S; Maniam R; Parhar I
    Sci Rep; 2021 Mar; 11(1):5549. PubMed ID: 33692406
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139.
    Isberg V; Andersen KB; Bisig C; Dietz GP; Bräuner-Osborne H; Gloriam DE
    J Chem Inf Model; 2014 Jun; 54(6):1553-7. PubMed ID: 24826842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP(+) and Rotenone Toxicity.
    Bayer Andersen K; Leander Johansen J; Hentzer M; Smith GP; Dietz GP
    Front Cell Neurosci; 2016; 10():164. PubMed ID: 27445691
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.