181 related articles for article (PubMed ID: 36746631)
1. Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD
Ratia KM; Shen Z; Gordon-Blake J; Lee H; Laham MS; Krider IS; Christie N; Ackerman-Berrier M; Penton C; Knowles NG; Musku SR; Fu J; Velma GR; Xiong R; Thatcher GRJ
Biochemistry; 2023 Feb; 62(4):923-933. PubMed ID: 36746631
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
Shen Z; Ratia K; Krider I; Ackerman-Berrier M; Penton C; Musku SR; Gordon-Blake JM; Laham MS; Christie N; Ma N; Fu J; Xiong R; Courey JM; Velma GR; Thatcher GRJ
J Med Chem; 2023 Dec; 66(24):16704-16727. PubMed ID: 38096366
[TBL] [Abstract][Full Text] [Related]
3. NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism.
Burgos ES
Curr Med Chem; 2011; 18(13):1947-61. PubMed ID: 21517777
[TBL] [Abstract][Full Text] [Related]
4. Identification of structural determinants of nicotinamide phosphoribosyl transferase (NAMPT) activity and substrate selectivity.
Houry D; Raasakka A; Ferrario E; Niere M; Bifulco E; Kursula P; Ziegler M
J Struct Biol; 2023 Sep; 215(3):108004. PubMed ID: 37495196
[TBL] [Abstract][Full Text] [Related]
5. Novel carbon skeletons activate human NicotinAMide Phosphoribosyl Transferase (NAMPT) enzyme in biochemical assay.
Almeida KH; Avalos-Irving L; Berardinelli S; Chauvin K; Yanez S
PLoS One; 2023; 18(3):e0283428. PubMed ID: 36996070
[TBL] [Abstract][Full Text] [Related]
6. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
Yang NC; Song TY; Chang YZ; Chen MY; Hu ML
Biogerontology; 2015 Feb; 16(1):31-42. PubMed ID: 25146190
[TBL] [Abstract][Full Text] [Related]
7. Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans.
Dutta T; Kapoor N; Mathew M; Chakraborty SS; Ward NP; Prieto-Farigua N; Falzone A; DeLany JP; Smith SR; Coen PM; DeNicola GM; Gardell SJ
Cell Rep; 2023 Mar; 42(3):112218. PubMed ID: 36897780
[TBL] [Abstract][Full Text] [Related]
8. Drug discovery targeting nicotinamide phosphoribosyltransferase (NAMPT): Updated progress and perspectives.
Wen F; Gui G; Wang X; Ye L; Qin A; Zhou C; Zha X
Bioorg Med Chem; 2024 Feb; 99():117595. PubMed ID: 38244254
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma P; Xu J; Williams K; Easley M; Elder JB; Lonser R; Lang FF; Lapalombella R; Sampath D; Puduvalli VK
Neuro Oncol; 2022 Feb; 24(2):229-244. PubMed ID: 34260721
[TBL] [Abstract][Full Text] [Related]
10. Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase.
Burgos ES; Schramm VL
Biochemistry; 2008 Oct; 47(42):11086-96. PubMed ID: 18823127
[TBL] [Abstract][Full Text] [Related]
11. Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry.
Hara N; Osago H; Hiyoshi M; Kobayashi-Miura M; Tsuchiya M
PLoS One; 2019; 14(3):e0214000. PubMed ID: 30875389
[TBL] [Abstract][Full Text] [Related]
12. Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models.
O'Brien T; Oeh J; Xiao Y; Liang X; Vanderbilt A; Qin A; Yang L; Lee LB; Ly J; Cosino E; LaCap JA; Ogasawara A; Williams S; Nannini M; Liederer BM; Jackson P; Dragovich PS; Sampath D
Neoplasia; 2013 Dec; 15(12):1314-29. PubMed ID: 24403854
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells.
Tan B; Dong S; Shepard RL; Kays L; Roth KD; Geeganage S; Kuo MS; Zhao G
J Biol Chem; 2015 Jun; 290(25):15812-15824. PubMed ID: 25944913
[TBL] [Abstract][Full Text] [Related]
14. Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity.
Yao H; Liu M; Wang L; Zu Y; Wu C; Li C; Zhang R; Lu H; Li F; Xi S; Chen S; Gu X; Liu T; Cai J; Wang S; Yang M; Xing GG; Xiong W; Hua L; Tang Y; Wang G
Cell Res; 2022 Jun; 32(6):570-584. PubMed ID: 35459935
[TBL] [Abstract][Full Text] [Related]
15. Identification of evolutionary and kinetic drivers of NAD-dependent signaling.
Bockwoldt M; Houry D; Niere M; Gossmann TI; Reinartz I; Schug A; Ziegler M; Heiland I
Proc Natl Acad Sci U S A; 2019 Aug; 116(32):15957-15966. PubMed ID: 31341085
[TBL] [Abstract][Full Text] [Related]
16. Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.
ElMokh O; Matsumoto S; Biniecka P; Bellotti A; Schaeuble K; Piacente F; Gallart-Ayala H; Ivanisevic J; Stamenkovic I; Nencioni A; Nahimana A; Duchosal MA
Cell Death Dis; 2022 Apr; 13(4):320. PubMed ID: 35396381
[TBL] [Abstract][Full Text] [Related]
17. A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Burgos ES; Ho MC; Almo SC; Schramm VL
Proc Natl Acad Sci U S A; 2009 Aug; 106(33):13748-53. PubMed ID: 19666527
[TBL] [Abstract][Full Text] [Related]
18. Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes.
Hsu CP; Oka S; Shao D; Hariharan N; Sadoshima J
Circ Res; 2009 Aug; 105(5):481-91. PubMed ID: 19661458
[TBL] [Abstract][Full Text] [Related]
19. SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Sociali G; Grozio A; Caffa I; Schuster S; Becherini P; Damonte P; Sturla L; Fresia C; Passalacqua M; Mazzola F; Raffaelli N; Garten A; Kiess W; Cea M; Nencioni A; Bruzzone S
FASEB J; 2019 Mar; 33(3):3704-3717. PubMed ID: 30514106
[TBL] [Abstract][Full Text] [Related]
20. Nicotinamide phosphoribosyltransferase (Nampt) affects the lineage fate determination of mesenchymal stem cells: a possible cause for reduced osteogenesis and increased adipogenesis in older individuals.
Li Y; He X; Li Y; He J; Anderstam B; Andersson G; Lindgren U
J Bone Miner Res; 2011 Nov; 26(11):2656-64. PubMed ID: 21812028
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]