These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 36747705)

  • 1. The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits.
    Mays SG; Hercules D; Ortlund EA; Okafor CD
    bioRxiv; 2023 Jan; ():. PubMed ID: 36747705
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits.
    Mays SG; Hercules D; Ortlund EA; Okafor CD
    Protein Sci; 2023 Oct; 32(10):e4754. PubMed ID: 37572334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A phospholipid mimetic targeting LRH-1 ameliorates colitis.
    Mays SG; D'Agostino EH; Flynn AR; Huang X; Wang G; Liu X; Millings EJ; Okafor CD; Patel A; Cato ML; Cornelison JL; Melchers D; Houtman R; Moore DD; Calvert JW; Jui NT; Ortlund EA
    Cell Chem Biol; 2022 Jul; 29(7):1174-1186.e7. PubMed ID: 35316658
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity.
    Musille PM; Kossmann BR; Kohn JA; Ivanov I; Ortlund EA
    J Biol Chem; 2016 Jan; 291(3):1411-26. PubMed ID: 26553876
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and Dynamics of the Liver Receptor Homolog 1-PGC1
    Mays SG; Okafor CD; Tuntland ML; Whitby RJ; Dharmarajan V; Stec J; Griffin PR; Ortlund EA
    Mol Pharmacol; 2017 Jul; 92(1):1-11. PubMed ID: 28363985
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists.
    Mays SG; Okafor CD; Whitby RJ; Goswami D; Stec J; Flynn AR; Dugan MC; Jui NT; Griffin PR; Ortlund EA
    J Biol Chem; 2016 Dec; 291(49):25281-25291. PubMed ID: 27694446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis for the regulation of the nuclear receptor LRH-1.
    Stein S; Schoonjans K
    Curr Opin Cell Biol; 2015 Apr; 33():26-34. PubMed ID: 25463843
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New High-Throughput Screen Discovers Novel Ligands of Full-Length Nuclear Receptor LRH-1.
    Malabanan MM; Chapagain P; Haratipour Z; Choi WJ; Orun AR; Blind RD
    ACS Chem Biol; 2023 May; 18(5):1101-1114. PubMed ID: 37074920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
    Cato ML; D'Agostino EH; Spurlin RM; Flynn AR; Cornelison JL; Johnson AM; Fujita RA; Abraham SM; Jui NT; Ortlund EA
    J Biol Chem; 2023 Aug; 299(8):104921. PubMed ID: 37328104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.
    Sablin EP; Blind RD; Uthayaruban R; Chiu HJ; Deacon AM; Das D; Ingraham HA; Fletterick RJ
    J Struct Biol; 2015 Dec; 192(3):342-348. PubMed ID: 26416531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.
    Koppen A; Houtman R; Pijnenburg D; Jeninga EH; Ruijtenbeek R; Kalkhoven E
    Mol Cell Proteomics; 2009 Oct; 8(10):2212-26. PubMed ID: 19596656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric mechanisms of nuclear receptors: insights from computational simulations.
    Mackinnon JA; Gallastegui N; Osguthorpe DJ; Hagler AT; Estébanez-Perpiñá E
    Mol Cell Endocrinol; 2014 Aug; 393(1-2):75-82. PubMed ID: 24911885
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor.
    Köhler C; Carlström G; Gunnarsson A; Weininger U; Tångefjord S; Ullah V; Lepistö M; Karlsson U; Papavoine T; Edman K; Akke M
    Sci Adv; 2020 Jul; 6(29):eabb5277. PubMed ID: 32832645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A conserved surface on the ligand binding domain of nuclear receptors for allosteric control.
    Buzón V; Carbó LR; Estruch SB; Fletterick RJ; Estébanez-Perpiñá E
    Mol Cell Endocrinol; 2012 Jan; 348(2):394-402. PubMed ID: 21878368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1.
    Sablin EP; Krylova IN; Fletterick RJ; Ingraham HA
    Mol Cell; 2003 Jun; 11(6):1575-85. PubMed ID: 12820970
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.
    Cato ML; Cornelison JL; Spurlin RM; Courouble VV; Patel AB; Flynn AR; Johnson AM; Okafor CD; Frank F; D'Agostino EH; Griffin PR; Jui NT; Ortlund EA
    J Med Chem; 2022 May; 65(9):6888-6902. PubMed ID: 35503419
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bilirubin is a new ligand for nuclear receptor Liver Receptor Homolog-1.
    Chapagain P; Haratipour Z; Malabanan MM; Choi WJ; Blind RD
    bioRxiv; 2024 Jun; ():. PubMed ID: 38853895
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.
    Ricketson D; Hostick U; Fang L; Yamamoto KR; Darimont BD
    J Mol Biol; 2007 May; 368(3):729-41. PubMed ID: 17367809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations.
    Jin Y; Duan M; Wang X; Kong X; Zhou W; Sun H; Liu H; Li D; Yu H; Li Y; Hou T
    J Chem Inf Model; 2019 Feb; 59(2):842-857. PubMed ID: 30658039
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Illuminating ligand-induced dynamics in nuclear receptors through MD simulations.
    Yu T; Sudhakar N; Okafor CD
    Biochim Biophys Acta Gene Regul Mech; 2024 Jun; 1867(2):195025. PubMed ID: 38614450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.