These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 36749938)

  • 1. Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
    Saint-Dizier F; Matthews TP; Gregson AM; Prevet H; McHardy T; Colombano G; Saville H; Rowlands M; Ewens C; McAndrew PC; Tomlin K; Guillotin D; Mak GW; Drosopoulos K; Poursaitidis I; Burke R; van Montfort R; Linardopoulos S; Collins I
    J Med Chem; 2023 Feb; 66(4):2622-2645. PubMed ID: 36749938
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET.
    Kleylein-Sohn J; Pöllinger B; Ohmer M; Hofmann F; Nigg EA; Hemmings BA; Wartmann M
    J Cell Sci; 2012 Nov; 125(Pt 22):5391-402. PubMed ID: 22946058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells.
    Kurisawa N; Yukawa M; Koshino H; Onodera T; Toda T; Kimura KI
    Bioorg Med Chem; 2020 Jan; 28(1):115154. PubMed ID: 31753800
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinesins regulate the heterogeneity in centrosome clustering after whole-genome duplication.
    Lau TT; Ma HT; Poon RY
    Life Sci Alliance; 2024 Oct; 7(10):. PubMed ID: 39074902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients.
    Pannu V; Rida PC; Ogden A; Turaga RC; Donthamsetty S; Bowen NJ; Rudd K; Gupta MV; Reid MD; Cantuaria G; Walczak CE; Aneja R
    Oncotarget; 2015 Mar; 6(8):6076-91. PubMed ID: 25788277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor Traffic.
    Reinemann DN; Norris SR; Ohi R; Lang MJ
    Curr Biol; 2018 Jul; 28(14):2356-2362.e5. PubMed ID: 30017484
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinesin-14 KIFC1 modulates spindle assembly and chromosome segregation in mouse spermatocytes.
    Wei YL; Fan XJ; Diao YY; She ZY; Wang XR
    Exp Cell Res; 2022 May; 414(1):113095. PubMed ID: 35259401
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas.
    Mittal K; Choi DH; Klimov S; Pawar S; Kaur R; Mitra AK; Gupta MV; Sams R; Cantuaria G; Rida PCG; Aneja R
    J Ovarian Res; 2016 Mar; 9():17. PubMed ID: 26992853
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification.
    Zhang C; Wu BZ; Di Ciano-Oliveira C; Wu YF; Khavkine Binstock SS; Soria-Bretones I; Pham NA; Elia AJ; Chari R; Lam WL; Bray MR; Mak TW; Tsao MS; Cescon DW; Thu KL
    Cancer Gene Ther; 2024 Oct; 31(10):1559-1570. PubMed ID: 39179685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction.
    Kalkan BM; Ozcan SC; Cicek E; Gonen M; Acilan C
    Cell Death Dis; 2024 Mar; 15(3):222. PubMed ID: 38493150
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.
    Watts CA; Richards FM; Bender A; Bond PJ; Korb O; Kern O; Riddick M; Owen P; Myers RM; Raff J; Gergely F; Jodrell DI; Ley SV
    Chem Biol; 2013 Nov; 20(11):1399-410. PubMed ID: 24210220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer.
    Chavali PL; Chandrasekaran G; Barr AR; Tátrai P; Taylor C; Papachristou EK; Woods CG; Chavali S; Gergely F
    Nat Commun; 2016 Mar; 7():11005. PubMed ID: 26987684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis.
    Vitre B; Taulet N; Guesdon A; Douanier A; Dosdane A; Cisneros M; Maurin J; Hettinger S; Anguille C; Taschner M; Lorentzen E; Delaval B
    EMBO Rep; 2020 Jun; 21(6):e49234. PubMed ID: 32270908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability.
    Chen S; Stout JR; Dharmaiah S; Yde S; Calvi BR; Walczak CE
    Mol Biol Cell; 2016 Oct; 27(19):2911-23. PubMed ID: 27489338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.
    Hata S; Pastor Peidro A; Panic M; Liu P; Atorino E; Funaya C; Jäkle U; Pereira G; Schiebel E
    Nat Cell Biol; 2019 Sep; 21(9):1138-1151. PubMed ID: 31481795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.
    Woodcock SA; Rushton HJ; Castañeda-Saucedo E; Myant K; White GR; Blyth K; Sansom OJ; Malliri A
    Curr Biol; 2010 Apr; 20(7):669-75. PubMed ID: 20346677
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EGF-induced centrosome separation promotes mitotic progression and cell survival.
    Mardin BR; Isokane M; Cosenza MR; Krämer A; Ellenberg J; Fry AM; Schiebel E
    Dev Cell; 2013 May; 25(3):229-40. PubMed ID: 23643362
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification.
    Saatci O; Akbulut O; Cetin M; Sikirzhytski V; Uner M; Lengerli D; O'Quinn EC; Romeo MJ; Caliskan B; Banoglu E; Aksoy S; Uner A; Sahin O
    Cell Death Differ; 2023 May; 30(5):1305-1319. PubMed ID: 36864125
    [TBL] [Abstract][Full Text] [Related]  

  • 19. KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries.
    Pawar S; Donthamsetty S; Pannu V; Rida P; Ogden A; Bowen N; Osan R; Cantuaria G; Aneja R
    J Ovarian Res; 2014; 7():53. PubMed ID: 25028599
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
    Koo CY; Giacomini C; Reyes-Corral M; Olmos Y; Tavares IA; Marson CM; Linardopoulos S; Tutt AN; Morris JDH
    Mol Cancer Ther; 2017 Nov; 16(11):2410-2421. PubMed ID: 28830982
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.