BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 36753963)

  • 1. The role of lysine-specific demethylase 6A (KDM6A) in tumorigenesis and its therapeutic potentials in cancer therapy.
    Chen LJ; Xu XY; Zhong XD; Liu YJ; Zhu MH; Tao F; Li CY; She QS; Yang GJ; Chen J
    Bioorg Chem; 2023 Apr; 133():106409. PubMed ID: 36753963
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
    Chang S; Yim S; Park H
    Exp Mol Med; 2019 Jun; 51(6):1-17. PubMed ID: 31221981
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lysine Demethylase KDM6A in Differentiation, Development, and Cancer.
    Tran N; Broun A; Ge K
    Mol Cell Biol; 2020 Sep; 40(20):. PubMed ID: 32817139
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The emerging roles of lysine-specific demethylase 4A in cancer: Implications in tumorigenesis and therapeutic opportunities.
    Yang G; Li C; Tao F; Liu Y; Zhu M; Du Y; Fei C; She Q; Chen J
    Genes Dis; 2024 Mar; 11(2):645-663. PubMed ID: 37692513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Diverse ways to be specific: a novel Zn-binding domain confers substrate specificity to UTX/KDM6A histone H3 Lys 27 demethylase.
    Kim E; Song JJ
    Genes Dev; 2011 Nov; 25(21):2223-6. PubMed ID: 22056667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Research Advances in Lysine-specific Demethylase 6A and Its Application in Treating Leukemia].
    Shen J; Zeng ZH; Yang L; Zeng MJ; Ouyang ZS; Zhao MY; Yang MH
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2019 Aug; 41(4):548-555. PubMed ID: 31484620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of JmjC-domain-containing histone demethylase (KDM2-7) inhibitors for cancer therapy.
    Zhang L; Chen Y; Li Z; Lin C; Zhang T; Wang G
    Drug Discov Today; 2023 May; 28(5):103519. PubMed ID: 36754142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vitamin C-dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition.
    Zhang T; Huang K; Zhu Y; Wang T; Shan Y; Long B; Li Y; Chen Q; Wang P; Zhao S; Li D; Wu C; Kang B; Gu J; Mai Y; Wang Q; Li J; Zhang Y; Liang Z; Guo L; Wu F; Su S; Wang J; Gao M; Zhong X; Liao B; Chen J; Zhang X; Shu X; Pei D; Nie J; Pan G
    J Biol Chem; 2019 Sep; 294(37):13657-13670. PubMed ID: 31341023
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature.
    Abu-Hanna J; Patel JA; Anastasakis E; Cohen R; Clapp LH; Loizidou M; Eddama MMR
    Clin Epigenetics; 2022 Aug; 14(1):98. PubMed ID: 35915507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The emerging role of KDM5A in human cancer.
    Yang GJ; Zhu MH; Lu XJ; Liu YJ; Lu JF; Leung CH; Ma DL; Chen J
    J Hematol Oncol; 2021 Feb; 14(1):30. PubMed ID: 33596982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalysis by KDM6 Histone Demethylases - A Synergy between the Non-Heme Iron(II) Center, Second Coordination Sphere, and Long-Range Interactions.
    Rifayee SBJS; Chaturvedi SS; Warner C; Wildey J; White W; Thompson M; Schofield CJ; Christov CZ
    Chemistry; 2023 Sep; 29(51):e202301305. PubMed ID: 37258457
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insights into histone lysine demethylation.
    Hou H; Yu H
    Curr Opin Struct Biol; 2010 Dec; 20(6):739-48. PubMed ID: 20970991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.
    Hong S; Cho YW; Yu LR; Yu H; Veenstra TD; Ge K
    Proc Natl Acad Sci U S A; 2007 Nov; 104(47):18439-44. PubMed ID: 18003914
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.
    Gažová I; Lengeling A; Summers KM
    Mol Genet Metab; 2019 May; 127(1):31-44. PubMed ID: 31097364
    [TBL] [Abstract][Full Text] [Related]  

  • 15. KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
    Boila LD; Ghosh S; Bandyopadhyay SK; Jin L; Murison A; Zeng AGX; Shaikh W; Bhowmik S; Muddineni SSNA; Biswas M; Sinha S; Chatterjee SS; Mbong N; Gan OI; Bose A; Chakraborty S; Arruda A; Kennedy JA; Mitchell A; Lechman ER; Banerjee D; Milyavsky M; Minden MD; Dick JE; Sengupta A
    Leukemia; 2023 Apr; 37(4):751-764. PubMed ID: 36720973
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.
    Walport LJ; Hopkinson RJ; Vollmar M; Madden SK; Gileadi C; Oppermann U; Schofield CJ; Johansson C
    J Biol Chem; 2014 Jun; 289(26):18302-13. PubMed ID: 24798337
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UTX Mutations in Human Cancer.
    Wang L; Shilatifard A
    Cancer Cell; 2019 Feb; 35(2):168-176. PubMed ID: 30753822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A.
    Sengoku T; Yokoyama S
    Genes Dev; 2011 Nov; 25(21):2266-77. PubMed ID: 22002947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal Epithelium.
    Kolev HM; Swisa A; Manduchi E; Lan Y; Stine RR; Testa G; Kaestner KH
    Cell Mol Gastroenterol Hepatol; 2023; 15(4):821-839. PubMed ID: 36503150
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3.
    Leng X; Wang J; An N; Wang X; Sun Y; Chen Z
    Oncogene; 2020 Oct; 39(41):6468-6479. PubMed ID: 32879445
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.