198 related articles for article (PubMed ID: 36757890)
1. Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA; Hu CJ; Pan H; Lu J; Abskharon R; Bowler JT; Rosenberg GM; Williams CK; Elezi G; Balbirnie M; Faull KF; Vinters HV; Seidler PM; Eisenberg DS
Proc Natl Acad Sci U S A; 2023 Feb; 120(7):e2217835120. PubMed ID: 36757890
[TBL] [Abstract][Full Text] [Related]
2. Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein.
Frieg B; Geraets JA; Strohäker T; Dienemann C; Mavroeidi P; Jung BC; Kim WS; Lee SJ; Xilouri M; Zweckstetter M; Schröder GF
Commun Biol; 2022 Sep; 5(1):1040. PubMed ID: 36180728
[TBL] [Abstract][Full Text] [Related]
3. Neurons with Cat's Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions.
De Giorgi F; Abdul-Shukkoor MB; Kashyrina M; Largitte LA; De Nuccio F; Kauffmann B; Lends A; Laferrière F; Bonhommeau S; Lofrumento DD; Bousset L; Bezard E; Buffeteau T; Loquet A; Ichas F
Biomolecules; 2022 Mar; 12(3):. PubMed ID: 35327628
[TBL] [Abstract][Full Text] [Related]
4. Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?
De Nuccio F; Kashyrina M; Serinelli F; Laferrière F; Lofrumento DD; De Giorgi F; Ichas F
Biomolecules; 2023 Feb; 13(2):. PubMed ID: 36830639
[TBL] [Abstract][Full Text] [Related]
5. Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.
Dhillon JS; Trejo-Lopez JA; Riffe C; Levites Y; Sacino AN; Borchelt DR; Yachnis AY; Giasson BI
Acta Neuropathol Commun; 2019 May; 7(1):80. PubMed ID: 31109378
[TBL] [Abstract][Full Text] [Related]
6. α-Synuclein: Experimental Pathology.
Hasegawa M; Nonaka T; Masuda-Suzukake M
Cold Spring Harb Perspect Med; 2016 Sep; 6(9):. PubMed ID: 27481772
[TBL] [Abstract][Full Text] [Related]
7. Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain.
Zhang S; Dauer K; Strohäker T; Tatenhorst L; Caldi Gomes L; Mayer S; Jung BC; Kim WS; Lee SJ; Becker S; Liesche-Starnecker F; Zweckstetter M; Lingor P
Brain Pathol; 2023 Sep; 33(5):e13196. PubMed ID: 37485772
[TBL] [Abstract][Full Text] [Related]
8. Neuropathology and molecular diagnosis of Synucleinopathies.
Koga S; Sekiya H; Kondru N; Ross OA; Dickson DW
Mol Neurodegener; 2021 Dec; 16(1):83. PubMed ID: 34922583
[TBL] [Abstract][Full Text] [Related]
9. Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.
Tarutani A; Arai T; Murayama S; Hisanaga SI; Hasegawa M
Acta Neuropathol Commun; 2018 Apr; 6(1):29. PubMed ID: 29669601
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Ardah MT; Ghanem SS; Abdulla SA; Lv G; Emara MM; Paleologou KE; Vaikath NN; Lu JH; Li M; Vekrellis K; Eliezer D; El-Agnaf OMA
BMC Complement Med Ther; 2020 Mar; 20(1):73. PubMed ID: 32143619
[TBL] [Abstract][Full Text] [Related]
11. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Pujols J; Peña-Díaz S; Lázaro DF; Peccati F; Pinheiro F; González D; Carija A; Navarro S; Conde-Giménez M; García J; Guardiola S; Giralt E; Salvatella X; Sancho J; Sodupe M; Outeiro TF; Dalfó E; Ventura S
Proc Natl Acad Sci U S A; 2018 Oct; 115(41):10481-10486. PubMed ID: 30249646
[TBL] [Abstract][Full Text] [Related]
12. Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics.
Yamasaki TR; Holmes BB; Furman JL; Dhavale DD; Su BW; Song ES; Cairns NJ; Kotzbauer PT; Diamond MI
J Biol Chem; 2019 Jan; 294(3):1045-1058. PubMed ID: 30478174
[TBL] [Abstract][Full Text] [Related]
13. Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
Sun C; Zhou K; DePaola P; Shin WS; Hillyer T; Sawaya MR; Zhu R; Peng C; Zhou ZH; Jiang L
J Biol Chem; 2023 Apr; 299(4):104566. PubMed ID: 36871760
[TBL] [Abstract][Full Text] [Related]
14. Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts.
Strohäker T; Jung BC; Liou SH; Fernandez CO; Riedel D; Becker S; Halliday GM; Bennati M; Kim WS; Lee SJ; Zweckstetter M
Nat Commun; 2019 Dec; 10(1):5535. PubMed ID: 31797870
[TBL] [Abstract][Full Text] [Related]
15. Electron Microscopic Analysis of α-Synuclein Fibrils.
Tarutani A; Hasegawa M
Methods Mol Biol; 2021; 2322():17-25. PubMed ID: 34043188
[TBL] [Abstract][Full Text] [Related]
16. Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons.
Tanudjojo B; Shaikh SS; Fenyi A; Bousset L; Agarwal D; Marsh J; Zois C; Heman-Ackah S; Fischer R; Sims D; Melki R; Tofaris GK
Nat Commun; 2021 Jun; 12(1):3817. PubMed ID: 34155194
[TBL] [Abstract][Full Text] [Related]
17. Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity.
Yang X; Williams JK; Yan R; Mouradian MM; Baum J
Sci Rep; 2019 Nov; 9(1):17579. PubMed ID: 31772376
[TBL] [Abstract][Full Text] [Related]
18. Altered α-synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains.
Brudek T; Winge K; Rasmussen NB; Bahl JM; Tanassi J; Agander TK; Hyde TM; Pakkenberg B
J Neurochem; 2016 Jan; 136(1):172-85. PubMed ID: 26465922
[TBL] [Abstract][Full Text] [Related]
19. The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies.
Van der Perren A; Gelders G; Fenyi A; Bousset L; Brito F; Peelaerts W; Van den Haute C; Gentleman S; Melki R; Baekelandt V
Acta Neuropathol; 2020 Jun; 139(6):977-1000. PubMed ID: 32356200
[TBL] [Abstract][Full Text] [Related]
20. α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species.
Morgan SA; Lavenir I; Fan J; Masuda-Suzukake M; Passarella D; DeTure MA; Dickson DW; Ghetti B; Goedert M
J Biol Chem; 2020 May; 295(19):6652-6664. PubMed ID: 32209651
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
