Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 36758176)

  • 1. IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model.
    Lutz V; Hellmund VM; Picard FSR; Raifer H; Ruckenbrod T; Klein M; Bopp T; Savai R; Duewell P; Keber CU; Weigert A; Chung HR; Buchholz M; Menke A; Gress TM; Huber M; Bauer C
    Cancer Immunol Res; 2023 Apr; 11(4):421-434. PubMed ID: 36758176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IL18 Receptor Signaling Inhibits Intratumoral CD8
    Nasiri E; Student M; Roth K; Siti Utami N; Huber M; Buchholz M; Gress TM; Bauer C
    Cells; 2023 Jan; 12(3):. PubMed ID: 36766797
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL18 at the Crossroads between Chronic Inflammation and T-cell Exhaustion in Pancreatic Cancer.
    Stromnes IM
    Cancer Immunol Res; 2023 Apr; 11(4):400. PubMed ID: 36897261
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.
    Wang J; Sun C; Gerdes N; Liu C; Liao M; Liu J; Shi MA; He A; Zhou Y; Sukhova GK; Chen H; Cheng XW; Kuzuya M; Murohara T; Zhang J; Cheng X; Jiang M; Shull GE; Rogers S; Yang CL; Ke Q; Jelen S; Bindels R; Ellison DH; Jarolim P; Libby P; Shi GP
    Nat Med; 2015 Jul; 21(7):820-6. PubMed ID: 26099046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion.
    Teagle AR; Castro-Sanchez P; Brownlie RJ; Logan N; Kapoor SS; Wright D; Salmond RJ; Zamoyska R
    J Immunother Cancer; 2023 Dec; 11(12):. PubMed ID: 38056892
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8
    Seo H; Chen J; González-Avalos E; Samaniego-Castruita D; Das A; Wang YH; López-Moyado IF; Georges RO; Zhang W; Onodera A; Wu CJ; Lu LF; Hogan PG; Bhandoola A; Rao A
    Proc Natl Acad Sci U S A; 2019 Jun; 116(25):12410-12415. PubMed ID: 31152140
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice.
    Liu CL; Ren J; Wang Y; Zhang X; Sukhova GK; Liao M; Santos M; Luo S; Yang D; Xia M; Inouye K; Hotamisligil GS; Lu G; Upchurch GR; Libby P; Guo J; Zhang J; Shi GP
    Eur Heart J; 2020 Jul; 41(26):2456-2468. PubMed ID: 31821481
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IL-2 regulates tumor-reactive CD8
    Liu Y; Zhou N; Zhou L; Wang J; Zhou Y; Zhang T; Fang Y; Deng J; Gao Y; Liang X; Lv J; Wang Z; Xie J; Xue Y; Zhang H; Ma J; Tang K; Fang Y; Cheng F; Zhang C; Dong B; Zhao Y; Yuan P; Gao Q; Zhang H; Xiao-Feng Qin F; Huang B
    Nat Immunol; 2021 Mar; 22(3):358-369. PubMed ID: 33432230
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer.
    Kim K; Park S; Park SY; Kim G; Park SM; Cho JW; Kim DH; Park YM; Koh YW; Kim HR; Ha SJ; Lee I
    Genome Med; 2020 Feb; 12(1):22. PubMed ID: 32111241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thymocyte selection-associated high mobility box protein regulates T lymphocytes exhaustion in patients with myelodysplastic syndromes by inhibiting PI3K/AKT/mTOR pathway.
    Niu H; Zhang M; Liu M; Yang L; Yang L; Ren J; Yu Y; Liu Y; Xing L; Shao Z; Wang H
    Hematol Oncol; 2024 Jan; 42(1):e3224. PubMed ID: 37712442
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Leveraging TCR Affinity in Adoptive Immunotherapy against Shared Tumor/Self-Antigens.
    Miller AM; Bahmanof M; Zehn D; Cohen EEW; Schoenberger SP
    Cancer Immunol Res; 2019 Jan; 7(1):40-49. PubMed ID: 30482746
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8
    Tillé L; Cropp D; Charmoy M; Reichenbach P; Andreatta M; Wyss T; Bodley G; Crespo I; Nassiri S; Lourenco J; Leblond MM; Lopez-Rodriguez C; Speiser DE; Coukos G; Irving M; Carmona SJ; Held W; Verdeil G
    Nat Immunol; 2023 Oct; 24(10):1645-1653. PubMed ID: 37709986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy.
    Mittal R; Wagener M; Breed ER; Liang Z; Yoseph BP; Burd EM; Farris AB; Coopersmith CM; Ford ML
    PLoS One; 2014; 9(5):e93523. PubMed ID: 24796533
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD8
    Farhood B; Najafi M; Mortezaee K
    J Cell Physiol; 2019 Jun; 234(6):8509-8521. PubMed ID: 30520029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.
    Xu A; Wang R; Freywald A; Stewart K; Tikoo S; Xu J; Zheng C; Xiang J
    Biochem Biophys Res Commun; 2017 Mar; 484(3):662-667. PubMed ID: 28153727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8
    Kundu ST; Rodriguez BL; Gibson LA; Warner AN; Perez MG; Bajaj R; Fradette JJ; Class CA; Solis LM; Rojas Alvarez FR; Wistuba II; Diao L; Chen F; Sachdeva M; Wang J; Kirsch DG; Creighton CJ; Gibbons DL
    Genes Dev; 2022 May; 36(9-10):582-600. PubMed ID: 35654454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proliferation and differentiation of CD8+ T cells in the absence of IL-2/15 receptor beta-chain expression or STAT5 activation.
    Teague RM; Tempero RM; Thomas S; Murali-Krishna K; Nelson BH
    J Immunol; 2004 Sep; 173(5):3131-9. PubMed ID: 15322173
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8
    Canale FP; Ramello MC; Núñez N; Araujo Furlan CL; Bossio SN; Gorosito Serrán M; Tosello Boari J; Del Castillo A; Ledesma M; Sedlik C; Piaggio E; Gruppi A; Acosta Rodríguez EA; Montes CL
    Cancer Res; 2018 Jan; 78(1):115-128. PubMed ID: 29066514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-β1 signaling.
    Grange M; Verdeil G; Arnoux F; Griffon A; Spicuglia S; Maurizio J; Buferne M; Schmitt-Verhulst AM; Auphan-Anezin N
    J Immunol; 2013 Oct; 191(7):3712-24. PubMed ID: 24006458
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of Cbl-b inhibits CD8
    Kumar J; Kumar R; Kumar Singh A; Tsakem EL; Kathania M; Riese MJ; Theiss AL; Davila ML; Venuprasad K
    J Immunother Cancer; 2021 Jan; 9(1):. PubMed ID: 33462140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.