175 related articles for article (PubMed ID: 36762206)
1. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme-A molecular insight.
Rodríguez Á; Maneiro M; Lence E; Otero JM; van Raaij MJ; Thompson P; Hawkins AR; González-Bello C
Front Mol Biosci; 2023; 10():1111598. PubMed ID: 36762206
[TBL] [Abstract][Full Text] [Related]
2. Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct.
González-Bello C; Tizón L; Lence E; Otero JM; van Raaij MJ; Martinez-Guitian M; Beceiro A; Thompson P; Hawkins AR
J Am Chem Soc; 2015 Jul; 137(29):9333-43. PubMed ID: 26148116
[TBL] [Abstract][Full Text] [Related]
3. Irreversible covalent modification of type I dehydroquinase with a stable Schiff base.
Tizón L; Maneiro M; Peón A; Otero JM; Lence E; Poza S; van Raaij MJ; Thompson P; Hawkins AR; González-Bello C
Org Biomol Chem; 2015 Jan; 13(3):706-16. PubMed ID: 25370445
[TBL] [Abstract][Full Text] [Related]
4. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product.
Lence E; Maneiro M; Sanz-Gaitero M; van Raaij MJ; Thompson P; Hawkins AR; González-Bello C
Chemistry; 2020 Jun; 26(36):8035-8044. PubMed ID: 32259333
[TBL] [Abstract][Full Text] [Related]
5. Specific chemical modification of bacterial type I dehydroquinase--opportunities for drug discovery.
González-Bello C
Future Med Chem; 2015; 7(17):2371-83. PubMed ID: 26599605
[TBL] [Abstract][Full Text] [Related]
6. Insights into substrate binding and catalysis in bacterial type I dehydroquinase.
Maneiro M; Peón A; Lence E; Otero JM; Van Raaij MJ; Thompson P; Hawkins AR; González-Bello C
Biochem J; 2014 Sep; 462(3):415-24. PubMed ID: 24957267
[TBL] [Abstract][Full Text] [Related]
7. Inversion of the roles of the nucleophile and acid/base catalysts in the covalent binding of epoxyalkyl xyloside inhibitor to the catalytic glutamates of endo-1,4-beta-xylanase (XYNII): a molecular dynamics study.
Laitinen T; Rouvinen J; Peräkylä M
Protein Eng; 2000 Apr; 13(4):247-52. PubMed ID: 10810155
[TBL] [Abstract][Full Text] [Related]
8. Control of metabolic flux through the quinate pathway in Aspergillus nidulans.
Wheeler KA; Lamb HK; Hawkins AR
Biochem J; 1996 Apr; 315 ( Pt 1)(Pt 1):195-205. PubMed ID: 8670107
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and evaluation of bifunctional inhibitors of type II dehydroquinase.
Toscano MD; Frederickson M; Evans DP; Coggins JR; Abell C; González-Bello C
Org Biomol Chem; 2003 Jun; 1(12):2075-83. PubMed ID: 12945898
[TBL] [Abstract][Full Text] [Related]
10. Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90.
Cuesta A; Wan X; Burlingame AL; Taunton J
J Am Chem Soc; 2020 Feb; 142(7):3392-3400. PubMed ID: 32009391
[TBL] [Abstract][Full Text] [Related]
11. Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).
Foffi G; Pastore A; Piazza F; Temussi PA
Phys Biol; 2013 Aug; 10(4):040301. PubMed ID: 23912807
[TBL] [Abstract][Full Text] [Related]
12. Stereospecific alkylation of cis-3-chloroacrylic acid dehalogenase by (R)-oxirane-2-carboxylate: analysis and mechanistic implications.
Poelarends GJ; Serrano H; Johnson WH; Whitman CP
Biochemistry; 2004 Jun; 43(22):7187-96. PubMed ID: 15170356
[TBL] [Abstract][Full Text] [Related]
13. Irreversible protein kinase inhibitors.
Garuti L; Roberti M; Bottegoni G
Curr Med Chem; 2011; 18(20):2981-94. PubMed ID: 21651479
[TBL] [Abstract][Full Text] [Related]
14. Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase.
Zhang X; Neamati N; Lee YK; Orr A; Brown RD; Whitaker N; Pommier Y; Burke TR
Bioorg Med Chem; 2001 Jul; 9(7):1649-57. PubMed ID: 11425564
[TBL] [Abstract][Full Text] [Related]
15. Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments.
Nichols CE; Lockyer M; Hawkins AR; Stammers DK
Proteins; 2004 Aug; 56(3):625-8. PubMed ID: 15229896
[No Abstract] [Full Text] [Related]
16. Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.
de Jong RM; Bazzacco P; Poelarends GJ; Johnson WH; Kim YJ; Burks EA; Serrano H; Thunnissen AM; Whitman CP; Dijkstra BW
J Biol Chem; 2007 Jan; 282(4):2440-9. PubMed ID: 17121835
[TBL] [Abstract][Full Text] [Related]
17. Covalent simulations of covalent/irreversible enzyme inhibition in drug discovery: a reliable technical protocol.
Khan S; Bjij I; Olotu FA; Agoni C; Adeniji E; S Soliman ME
Future Med Chem; 2018 Oct; 10(19):2265-2275. PubMed ID: 30273013
[TBL] [Abstract][Full Text] [Related]
18. A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides.
Palazzesi F; Grundl MA; Pautsch A; Weber A; Tautermann CS
J Chem Inf Model; 2019 Aug; 59(8):3565-3571. PubMed ID: 31246457
[TBL] [Abstract][Full Text] [Related]
19. Distinguishing the optimal binding mechanism through reversible and irreversible inhibition analysis of HSP72 protein in cancer therapy.
Aljoundi A; El Rashedy A; Soliman MES
Comput Biol Med; 2021 May; 132():104301. PubMed ID: 33751994
[TBL] [Abstract][Full Text] [Related]
20. Inactivation of delta 5-3-oxo steroid isomerase with active-site-directed acetylenic steroids.
Penning TM; Covey DF; Talalay P
Biochem J; 1981 Jan; 193(1):217-27. PubMed ID: 7305923
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
