193 related articles for article (PubMed ID: 36763058)
1. Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.
Ma D; Zhong L; Yan Z; Yao J; Zhang Y; Ye F; Huang Y; Lai D; Yang W; Hou P; Guo J
Proc Natl Acad Sci U S A; 2022 Nov; 119(45):e2207067119. PubMed ID: 36763058
[TBL] [Abstract][Full Text] [Related]
2. The membrane electric field regulates the PIP
Mandala VS; MacKinnon R
Proc Natl Acad Sci U S A; 2023 May; 120(21):e2301985120. PubMed ID: 37192161
[TBL] [Abstract][Full Text] [Related]
3. ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling.
Hou P; Shi J; White KM; Gao Y; Cui J
Elife; 2019 Jul; 8():. PubMed ID: 31329101
[TBL] [Abstract][Full Text] [Related]
4. Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Sun J; MacKinnon R
Cell; 2017 Jun; 169(6):1042-1050.e9. PubMed ID: 28575668
[TBL] [Abstract][Full Text] [Related]
5. Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening.
Kang PW; Westerlund AM; Shi J; White KM; Dou AK; Cui AH; Silva JR; Delemotte L; Cui J
Sci Adv; 2020 Dec; 6(50):. PubMed ID: 33310856
[TBL] [Abstract][Full Text] [Related]
6. Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
Willegems K; Eldstrom J; Kyriakis E; Ataei F; Sahakyan H; Dou Y; Russo S; Van Petegem F; Fedida D
Nat Commun; 2022 Jun; 13(1):3760. PubMed ID: 35768468
[TBL] [Abstract][Full Text] [Related]
7. Structural Basis of Human KCNQ1 Modulation and Gating.
Sun J; MacKinnon R
Cell; 2020 Jan; 180(2):340-347.e9. PubMed ID: 31883792
[TBL] [Abstract][Full Text] [Related]
8. A PIP
Liu Y; Xu X; Gao J; Naffaa MM; Liang H; Shi J; Wang HZ; Yang ND; Hou P; Zhao W; White KM; Kong W; Dou A; Cui A; Zhang G; Cohen IS; Zou X; Cui J
Commun Biol; 2020 Jul; 3(1):385. PubMed ID: 32678288
[TBL] [Abstract][Full Text] [Related]
9. Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1.
Nekouzadeh A; Rudy Y
Prog Biophys Mol Biol; 2016 Jan; 120(1-3):18-27. PubMed ID: 26743208
[TBL] [Abstract][Full Text] [Related]
10. A general mechanism of KCNE1 modulation of KCNQ1 channels involving non-canonical VSD-PD coupling.
Wu X; Perez ME; Noskov SY; Larsson HP
Commun Biol; 2021 Jul; 4(1):887. PubMed ID: 34285340
[TBL] [Abstract][Full Text] [Related]
11. Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments.
Xu Y; Wang Y; Zhang M; Jiang M; Rosenhouse-Dantsker A; Wassenaar T; Tseng GN
Biophys J; 2015 Jan; 108(1):62-75. PubMed ID: 25564853
[TBL] [Abstract][Full Text] [Related]
12. Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes.
Wang Y; Eldstrom J; Fedida D
Front Physiol; 2020; 11():504. PubMed ID: 32581825
[TBL] [Abstract][Full Text] [Related]
13. KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions.
Barro-Soria R; Ramentol R; Liin SI; Perez ME; Kass RS; Larsson HP
Proc Natl Acad Sci U S A; 2017 Aug; 114(35):E7367-E7376. PubMed ID: 28808020
[TBL] [Abstract][Full Text] [Related]
14. Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements.
Chen L; Peng G; Comollo TW; Zou X; Sampson KJ; Larsson HP; Kass RS
Front Physiol; 2022; 13():903050. PubMed ID: 35957984
[TBL] [Abstract][Full Text] [Related]
15. Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening.
Nakajo K; Kubo Y
Nat Commun; 2014 Jun; 5():4100. PubMed ID: 24920132
[TBL] [Abstract][Full Text] [Related]
16. The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure.
Labro AJ; Boulet IR; Choveau FS; Mayeur E; Bruyns T; Loussouarn G; Raes AL; Snyders DJ
J Biol Chem; 2011 Jan; 286(1):717-25. PubMed ID: 21059661
[TBL] [Abstract][Full Text] [Related]
17. ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state.
Eldstrom J; McAfee DA; Dou Y; Wang Y; Fedida D
J Gen Physiol; 2021 Dec; 153(12):. PubMed ID: 34636894
[TBL] [Abstract][Full Text] [Related]
18. KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain.
Choveau FS; Rodriguez N; Abderemane Ali F; Labro AJ; Rose T; Dahimène S; Boudin H; Le Hénaff C; Escande D; Snyders DJ; Charpentier F; Mérot J; Baró I; Loussouarn G
J Biol Chem; 2011 Jan; 286(1):707-16. PubMed ID: 20940310
[TBL] [Abstract][Full Text] [Related]
19. Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening.
Hou P; Eldstrom J; Shi J; Zhong L; McFarland K; Gao Y; Fedida D; Cui J
Nat Commun; 2017 Nov; 8(1):1730. PubMed ID: 29167462
[TBL] [Abstract][Full Text] [Related]
20. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels.
Yu H; Lin Z; Mattmann ME; Zou B; Terrenoire C; Zhang H; Wu M; McManus OB; Kass RS; Lindsley CW; Hopkins CR; Li M
Proc Natl Acad Sci U S A; 2013 May; 110(21):8732-7. PubMed ID: 23650380
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
