These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 36764521)

  • 1. The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD.
    Li Y; Geng J; Rimal S; Wang H; Liu X; Lu B; Li S
    J Biol Chem; 2023 Mar; 299(3):102995. PubMed ID: 36764521
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.
    Li S; Wu Z; Tantray I; Li Y; Chen S; Dong J; Glynn S; Vogel H; Snyder M; Lu B
    Proc Natl Acad Sci U S A; 2020 Oct; 117(40):25104-25115. PubMed ID: 32958650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
    Saberi S; Stauffer JE; Jiang J; Garcia SD; Taylor AE; Schulte D; Ohkubo T; Schloffman CL; Maldonado M; Baughn M; Rodriguez MJ; Pizzo D; Cleveland D; Ravits J
    Acta Neuropathol; 2018 Mar; 135(3):459-474. PubMed ID: 29196813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD.
    Taminato T; Takeuchi T; Ueyama M; Mori K; Ikeda M; Mochizuki H; Nagai Y
    Hum Mol Genet; 2023 May; 32(10):1673-1682. PubMed ID: 36611007
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
    Solomon DA; Stepto A; Au WH; Adachi Y; Diaper DC; Hall R; Rekhi A; Boudi A; Tziortzouda P; Lee YB; Smith B; Bridi JC; Spinelli G; Dearlove J; Humphrey DM; Gallo JM; Troakes C; Fanto M; Soller M; Rogelj B; Parsons RB; Shaw CE; Hortobágyi T; Hirth F
    Brain; 2018 Oct; 141(10):2908-2924. PubMed ID: 30239641
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
    Park J; Lee J; Kim JH; Lee J; Park H; Lim C
    Nucleic Acids Res; 2021 Nov; 49(19):11294-11311. PubMed ID: 34551427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD.
    Fu X; Zhang Z; Hayes LR; Wright N; Asbury J; Li S; Ye Y; Sun S
    Exp Neurol; 2024 Jun; 376():114768. PubMed ID: 38556190
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD.
    Yuva-Aydemir Y; Almeida S; Krishnan G; Gendron TF; Gao FB
    Nat Commun; 2019 Nov; 10(1):5466. PubMed ID: 31784536
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in
    Fujino Y; Ueyama M; Ishiguro T; Ozawa D; Ito H; Sugiki T; Murata A; Ishiguro A; Gendron T; Mori K; Tokuda E; Taminato T; Konno T; Koyama A; Kawabe Y; Takeuchi T; Furukawa Y; Fujiwara T; Ikeda M; Mizuno T; Mochizuki H; Mizusawa H; Wada K; Ishikawa K; Onodera O; Nakatani K; Petrucelli L; Taguchi H; Nagai Y
    Elife; 2023 Jul; 12():. PubMed ID: 37461319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis.
    Trageser KJ; Yang EJ; Smith C; Iban-Arias R; Oguchi T; Sebastian-Valverde M; Iqbal UH; Wu H; Estill M; Al Rahim M; Raval U; Herman FJ; Zhang YJ; Petrucelli L; Pasinetti GM
    Mol Neurobiol; 2023 Jul; 60(7):4004-4016. PubMed ID: 37010807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Poly-GR repeats associated with ALS/FTD gene
    Dong D; Zhang Z; Li Y; Latallo MJ; Wang S; Nelson B; Wu R; Krishnan G; Gao FB; Wu B; Sun S
    Sci Signal; 2024 Aug; 17(848):eadl1030. PubMed ID: 39106320
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metformin ameliorates mitochondrial damage induced by C9orf72 poly(GR) via upregulating AKT phosphorylation.
    Feng Y; Xu Z; Jin H; Chen Y; Fu C; Zhang Y; Yin Y; Wang H; Cheng W
    J Cell Biochem; 2024 Mar; 125(3):e30526. PubMed ID: 38229533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
    Odeh HM; Shorter J
    Emerg Top Life Sci; 2020 Dec; 4(3):293-305. PubMed ID: 32639008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
    Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
    Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
    Zhang YJ; Gendron TF; Ebbert MTW; O'Raw AD; Yue M; Jansen-West K; Zhang X; Prudencio M; Chew J; Cook CN; Daughrity LM; Tong J; Song Y; Pickles SR; Castanedes-Casey M; Kurti A; Rademakers R; Oskarsson B; Dickson DW; Hu W; Gitler AD; Fryer JD; Petrucelli L
    Nat Med; 2018 Aug; 24(8):1136-1142. PubMed ID: 29942091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Translation of the poly(GR) frame in C9ORF72-ALS/FTD is regulated by cis-elements involved in alternative splicing.
    Lampasona A; Almeida S; Gao FB
    Neurobiol Aging; 2021 Sep; 105():327-332. PubMed ID: 34157654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.