BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 36768638)

  • 1. The ATR Inhibitor VE-821 Enhances the Radiosensitivity and Suppresses DNA Repair Mechanisms of Human Chondrosarcoma Cells.
    Lohberger B; Glänzer D; Eck N; Stasny K; Falkner A; Leithner A; Georg D
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768638
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of ATR kinase with the selective inhibitor VE-821 results in radiosensitization of cells of promyelocytic leukaemia (HL-60).
    Vávrová J; Zárybnická L; Lukášová E; Řezáčová M; Novotná E; Sinkorová Z; Tichý A; Pejchal J; Durišová K
    Radiat Environ Biophys; 2013 Nov; 52(4):471-9. PubMed ID: 23934411
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
    Prevo R; Fokas E; Reaper PM; Charlton PA; Pollard JR; McKenna WG; Muschel RJ; Brunner TB
    Cancer Biol Ther; 2012 Sep; 13(11):1072-81. PubMed ID: 22825331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells.
    Šalovská B; Janečková H; Fabrik I; Karlíková R; Čecháková L; Ondrej M; Link M; Friedecký D; Tichý A
    PLoS One; 2018; 13(7):e0199349. PubMed ID: 30001349
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.
    Middleton FK; Patterson MJ; Elstob CJ; Fordham S; Herriott A; Wade MA; McCormick A; Edmondson R; May FE; Allan JM; Pollard JR; Curtin NJ
    Oncotarget; 2015 Oct; 6(32):32396-409. PubMed ID: 26486089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sulfoximines as ATR inhibitors: Analogs of VE-821.
    Hendriks CMM; Hartkamp J; Wiezorek S; Steinkamp AD; Rossetti G; Lüscher B; Bolm C
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2659-2662. PubMed ID: 28479198
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The antiproliferative effects of ataxia-telangiectasia mutated and ATM- and Rad3-related inhibitions and their enhancements with the cytotoxicity of DNA damaging agents in cholangiocarcinoma cells.
    Moolmuang B; Ruchirawat M
    J Pharm Pharmacol; 2021 Mar; 73(1):40-51. PubMed ID: 33791808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ZEB1 inhibition sensitizes cells to the ATR inhibitor VE-821 by abrogating epithelial-mesenchymal transition and enhancing DNA damage.
    Song N; Jing W; Li C; Bai M; Cheng Y; Li H; Hou K; Li Y; Wang K; Li Z; Liu Y; Qu X; Che X
    Cell Cycle; 2018; 17(5):595-604. PubMed ID: 29157079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small-molecule inhibitors of Ataxia Telangiectasia and Rad3 related kinase (ATR) sensitize lymphoma cells to UVA radiation.
    Biskup E; Naym DG; Gniadecki R
    J Dermatol Sci; 2016 Dec; 84(3):239-247. PubMed ID: 27743911
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor-specific radiosensitizing effect of the ATM inhibitor AZD0156 in melanoma cells with low toxicity to healthy fibroblasts.
    Scheper J; Hildebrand LS; Faulhaber EM; Deloch L; Gaipl US; Symank J; Fietkau R; Distel LV; Hecht M; Jost T
    Strahlenther Onkol; 2023 Dec; 199(12):1128-1139. PubMed ID: 36229655
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation.
    Fujisawa H; Nakajima NI; Sunada S; Lee Y; Hirakawa H; Yajima H; Fujimori A; Uesaka M; Okayasu R
    Radiat Oncol; 2015 Aug; 10():175. PubMed ID: 26286029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.
    Pires IM; Olcina MM; Anbalagan S; Pollard JR; Reaper PM; Charlton PA; McKenna WG; Hammond EM
    Br J Cancer; 2012 Jul; 107(2):291-9. PubMed ID: 22713662
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined poly-ADP ribose polymerase and ataxia-telangiectasia mutated/Rad3-related inhibition targets ataxia-telangiectasia mutated-deficient lung cancer cells.
    Jette NR; Radhamani S; Arthur G; Ye R; Goutam S; Bolyos A; Petersen LF; Bose P; Bebb DG; Lees-Miller SP
    Br J Cancer; 2019 Oct; 121(7):600-610. PubMed ID: 31481733
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Radiosensitization of human leukemic HL-60 cells by ATR kinase inhibitor (VE-821): phosphoproteomic analysis.
    Šalovská B; Fabrik I; Ďurišová K; Link M; Vávrová J; Řezáčová M; Tichý A
    Int J Mol Sci; 2014 Jul; 15(7):12007-26. PubMed ID: 25003641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinase Inhibitors of DNA-PK, ATM and ATR in Combination with Ionizing Radiation Can Increase Tumor Cell Death in HNSCC Cells While Sparing Normal Tissue Cells.
    Faulhaber EM; Jost T; Symank J; Scheper J; Bürkel F; Fietkau R; Hecht M; Distel LV
    Genes (Basel); 2021 Jun; 12(6):. PubMed ID: 34204447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATR kinase inhibition sensitizes quiescent human cells to the lethal effects of cisplatin but increases mutagenesis.
    Hutcherson RJ; Kemp MG
    Mutat Res; 2019 Nov; 816-818():111678. PubMed ID: 31557599
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments.
    Mohni KN; Thompson PS; Luzwick JW; Glick GG; Pendleton CS; Lehmann BD; Pietenpol JA; Cortez D
    PLoS One; 2015; 10(5):e0125482. PubMed ID: 25965342
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of [
    Carlucci G; Carney B; Sadique A; Vansteene A; Tang J; Reiner T
    Nucl Med Biol; 2017 May; 48():9-15. PubMed ID: 28157626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells.
    Dobler C; Jost T; Hecht M; Fietkau R; Distel L
    Cells; 2020 Sep; 9(9):. PubMed ID: 32883016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.
    Fokas E; Prevo R; Pollard JR; Reaper PM; Charlton PA; Cornelissen B; Vallis KA; Hammond EM; Olcina MM; Gillies McKenna W; Muschel RJ; Brunner TB
    Cell Death Dis; 2012 Dec; 3(12):e441. PubMed ID: 23222511
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.