BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

76 related articles for article (PubMed ID: 36769169)

  • 1. A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
    Brenner D; Sieverding K; Srinidhi J; Zellner S; Secker C; Yilmaz R; Dyckow J; Amr S; Ponomarenko A; Tunaboylu E; Douahem Y; Schlag JS; Rodríguez Martínez L; Kislinger G; Niemann C; Nalbach K; Ruf WP; Uhl J; Hollenbeck J; Schirmer L; Catanese A; Lobsiger CS; Danzer KM; Yilmazer-Hanke D; Münch C; Koch P; Freischmidt A; Fetting M; Behrends C; Parlato R; Weishaupt JH
    J Exp Med; 2024 May; 221(5):. PubMed ID: 38517332
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coexistence of variants in TBK1 and in other ALS-related genes elucidates an oligogenic model of pathogenesis in sporadic ALS.
    Lattante S; Doronzio PN; Marangi G; Conte A; Bisogni G; Bernardo D; Russo T; Lamberti D; Patrizi S; Apollo FP; Lunetta C; Scarlino S; Pozzi L; Zollino M; Riva N; Sabatelli M
    Neurobiol Aging; 2019 Dec; 84():239.e9-239.e14. PubMed ID: 31000212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TBK1 promotes thyroid cancer progress by activating the PI3K/Akt/mTOR signaling pathway.
    Jiang Q; Guan Y; Zheng J; Lu H
    Immun Inflamm Dis; 2023 Mar; 11(3):e796. PubMed ID: 36988258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Serine/threonine kinase TBK1 promotes cholangiocarcinoma progression via direct regulation of β-catenin.
    Gao CQ; Chu ZZ; Zhang D; Xiao Y; Zhou XY; Wu JR; Yuan H; Jiang YC; Chen D; Zhang JC; Yao N; Chen KY; Hong J
    Oncogene; 2023 May; 42(18):1492-1507. PubMed ID: 36928362
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mendelian Randomization Analysis Reveals Statins Potentially Increase Amyotrophic Lateral Sclerosis Risk Independent of Peripheral Cholesterol-Lowering Effects.
    Wang W; Zhang L; Xia K; Huang T; Fan D
    Biomedicines; 2023 May; 11(5):. PubMed ID: 37239030
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders.
    De Marchi F; Munitic I; Vidatic L; Papić E; Rački V; Nimac J; Jurak I; Novotni G; Rogelj B; Vuletic V; Liscic RM; Cannon JR; Buratti E; Mazzini L; Hecimovic S
    Biomedicines; 2023 Oct; 11(10):. PubMed ID: 37893165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyotrophic Lateral Sclerosis as a Systemic Disease.
    Moresi V
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Association between TBK1 mutations and risk of amyotrophic lateral sclerosis/frontotemporal dementia spectrum: a meta-analysis.
    Cui R; Tuo M; Li P; Zhou C
    Neurol Sci; 2018 May; 39(5):811-820. PubMed ID: 29349657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional Characterization of a Familial ALS-Associated Missense
    Porras G; Ruiz S; Maestro I; Borrego-Hernández D; Redondo AG; Martínez A; Martín-Requero Á
    Int J Mol Sci; 2023 Feb; 24(3):. PubMed ID: 36769169
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation.
    Foster AD; Downing P; Figredo E; Polain N; Stott A; Layfield R; Rea SL
    Mol Cell Neurosci; 2020 Oct; 108():103539. PubMed ID: 32835772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional and structural consequences of TBK1 missense variants in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Gurfinkel Y; Polain N; Sonar K; Nice P; Mancera RL; Rea SL
    Neurobiol Dis; 2022 Nov; 174():105859. PubMed ID: 36113750
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.
    Harding O; Evans CS; Ye J; Cheung J; Maniatis T; Holzbaur ELF
    Proc Natl Acad Sci U S A; 2021 Jun; 118(24):. PubMed ID: 34099552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
    van der Zee J; Gijselinck I; Van Mossevelde S; Perrone F; Dillen L; Heeman B; Bäumer V; Engelborghs S; De Bleecker J; Baets J; Gelpi E; Rojas-García R; Clarimón J; Lleó A; Diehl-Schmid J; Alexopoulos P; Perneczky R; Synofzik M; Just J; Schöls L; Graff C; Thonberg H; Borroni B; Padovani A; Jordanova A; Sarafov S; Tournev I; de Mendonça A; Miltenberger-Miltényi G; Simões do Couto F; Ramirez A; Jessen F; Heneka MT; Gómez-Tortosa E; Danek A; Cras P; Vandenberghe R; De Jonghe P; De Deyn PP; Sleegers K; Cruts M; Van Broeckhoven C; Goeman J; Nuytten D; Smets K; Robberecht W; Damme PV; Bleecker J; Santens P; Dermaut B; Versijpt J; Michotte A; Ivanoiu A; Deryck O; Bergmans B; Delbeck J; Bruyland M; Willems C; Salmon E; Pastor P; Ortega-Cubero S; Benussi L; Ghidoni R; Binetti G; Hernández I; Boada M; Ruiz A; Sorbi S; Nacmias B; Bagnoli S; Sorbi S; Sanchez-Valle R; Llado A; Santana I; Rosário Almeida M; Frisoni GB; Maetzler W; Matej R; Fraidakis MJ; Kovacs GG; Fabrizi GM; Testi S
    Hum Mutat; 2017 Mar; 38(3):297-309. PubMed ID: 28008748
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity.
    Ye J; Cheung J; Gerbino V; Ahlsén G; Zimanyi C; Hirsh D; Maniatis T
    Proc Natl Acad Sci U S A; 2019 Dec; 116(49):24517-24526. PubMed ID: 31748271
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.