229 related articles for article (PubMed ID: 36769327)
21. Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
Zayed MF; Ahmed S; Ihmaid S; Ahmed HEA; Rateb HS; Ibrahim SRM
Int J Mol Sci; 2018 Jun; 19(6):. PubMed ID: 29891789
[TBL] [Abstract][Full Text] [Related]
22. Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma.
Zhai S; Zhang H; Chen R; Wu J; Ai D; Tao S; Cai Y; Zhang JQ; Wang L
Eur J Med Chem; 2021 Dec; 225():113824. PubMed ID: 34509167
[TBL] [Abstract][Full Text] [Related]
23. 1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and
Hagras M; Saleh MA; Ezz Eldin RR; Abuelkhir AA; Khidr EG; El-Husseiny AA; El-Mahdy HA; Elkaeed EB; Eissa IH
J Enzyme Inhib Med Chem; 2022 Dec; 37(1):380-396. PubMed ID: 34923885
[TBL] [Abstract][Full Text] [Related]
24. Design, synthesis and biological evaluation of 3,4-diaryl-1,2,5-oxadiazole-2/5-oxides as highly potent inhibitors of tubulin polymerization.
Hong Y; Zhao Y; Yang L; Gao M; Li L; Man S; Wang Z; Guan Q; Bao K; Zuo D; Wu Y; Zhang W
Eur J Med Chem; 2019 Sep; 178():287-296. PubMed ID: 31195170
[TBL] [Abstract][Full Text] [Related]
25. Synthesis, cytotoxicity, and molecular docking of substituted 3-(2-methylbenzofuran-3-yl)-5-(phenoxymethyl)-1,2,4-oxadiazoles.
Mokenapelli S; Thalari G; Vadiyaala N; Yerrabelli JR; Irlapati VK; Gorityala N; Sagurthi SR; Chitneni PR
Arch Pharm (Weinheim); 2020 Jun; 353(6):e2000006. PubMed ID: 32309890
[TBL] [Abstract][Full Text] [Related]
26. Structure-Based Virtual Screening of Furan-1,3,4-Oxadiazole Tethered
Irfan A; Faisal S; Ahmad S; Al-Hussain SA; Javed S; Zahoor AF; Parveen B; Zaki MEA
Pharmaceuticals (Basel); 2023 Feb; 16(3):. PubMed ID: 36986444
[TBL] [Abstract][Full Text] [Related]
27. Design, synthesis and pharmacological evaluation of 2-arylurea-1,3,5-triazine derivative (XIN-9): A novel potent dual PI3K/mTOR inhibitor for cancer therapy.
Sun X; Zhang B; Luo L; Yang Y; He B; Zhang Q; Wang L; Xu S; Zheng P; Zhu W
Bioorg Chem; 2022 Dec; 129():106157. PubMed ID: 36209563
[TBL] [Abstract][Full Text] [Related]
28. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
[TBL] [Abstract][Full Text] [Related]
29. Introducing of acyclonucleoside analogues tethered 1,2,4-triazole as anticancer agents with dual epidermal growth factor receptor kinase and microtubule inhibitors.
Aouad MR; Al-Mohammadi HM; Al-Blewi FF; Ihmaid S; Elbadawy HM; Althagfan SS; Rezki N
Bioorg Chem; 2020 Jan; 94():103446. PubMed ID: 31791685
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis, chemical characterization, biological evaluation, and docking study of new 1,3,4-oxadiazole homonucleoside analogs.
El Mansouri AE; Maatallah M; Ait Benhassou H; Moumen A; Mehdi A; Snoeck R; Andrei G; Zahouily M; Lazrek HB
Nucleosides Nucleotides Nucleic Acids; 2020; 39(8):1088-1107. PubMed ID: 32397827
[TBL] [Abstract][Full Text] [Related]
31. Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells.
Patel OPS; Arun A; Singh PK; Saini D; Karade SS; Chourasia MK; Konwar R; Yadav PP
Eur J Med Chem; 2019 Apr; 167():226-244. PubMed ID: 30772606
[TBL] [Abstract][Full Text] [Related]
32. Design, synthesis and biological evaluation of thieno[3,2-d]pyrimidine derivatives containing aroyl hydrazone or aryl hydrazide moieties for PI3K and mTOR dual inhibition.
Han Y; Tian Y; Wang R; Fu S; Jiang J; Dong J; Qin M; Hou Y; Zhao Y
Bioorg Chem; 2020 Nov; 104():104197. PubMed ID: 32927132
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding.
Sigalapalli DK; Kiranmai G; Parimala Devi G; Tokala R; Sana S; Tripura C; Jadhav GS; Kadagathur M; Shankaraiah N; Nagesh N; Babu BN; Tangellamudi ND
Bioorg Med Chem; 2021 Aug; 43():116277. PubMed ID: 34175586
[TBL] [Abstract][Full Text] [Related]
34. Ultrasonic-Assisted Synthesis of Benzofuran Appended Oxadiazole Molecules as Tyrosinase Inhibitors: Mechanistic Approach through Enzyme Inhibition, Molecular Docking, Chemoinformatics, ADMET and Drug-Likeness Studies.
Irfan A; Zahoor AF; Kamal S; Hassan M; Kloczkowski A
Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142889
[TBL] [Abstract][Full Text] [Related]
35. Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and
Eldehna WM; Al-Rashood ST; Al-Warhi T; Eskandrani RO; Alharbi A; El Kerdawy AM
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):270-285. PubMed ID: 33327806
[TBL] [Abstract][Full Text] [Related]
36. New 1,3,4-oxadiazoles linked with the 1,2,3-triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase.
Mahmoud MA; Mohammed AF; Salem OIA; Gomaa HAM; Youssif BGM
Arch Pharm (Weinheim); 2022 Jun; 355(6):e2200009. PubMed ID: 35195309
[TBL] [Abstract][Full Text] [Related]
37. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
Alswah M; Bayoumi AH; Elgamal K; Elmorsy A; Ihmaid S; Ahmed HEA
Molecules; 2017 Dec; 23(1):. PubMed ID: 29280968
[TBL] [Abstract][Full Text] [Related]
38. Synthesis of alkynylated 1,2,4-oxadiazole/1,2,3-1H-triazole glycoconjugates: Discovering new compounds for use in chemotherapy against lung carcinoma and Mycobacterium tuberculosis.
Melo de Oliveira VN; Flávia do Amaral Moura C; Peixoto ADS; Gonçalves Ferreira VP; Araújo HM; Lapa Montenegro Pimentel LM; Pessoa CDÓ; Nicolete R; Versiani Dos Anjos J; Sharma PP; Rathi B; Pena LJ; Rollin P; Tatibouët A; Nascimento de Oliveira R
Eur J Med Chem; 2021 Aug; 220():113472. PubMed ID: 33940463
[TBL] [Abstract][Full Text] [Related]
39. Design, synthesis and molecular docking of novel substituted azepines as inhibitors of PI3K/Akt/TSC2/mTOR signaling pathway in colorectal carcinoma.
Noser AA; Abdelmonsef AH; Salem MM
Bioorg Chem; 2023 Feb; 131():106299. PubMed ID: 36493622
[TBL] [Abstract][Full Text] [Related]
40. A Review: Discovering 1,3,4-oxadiazole and Chalcone Nucleus for Cytotoxicity / EGFR Inhibitory Anticancer Activity.
Patil S; Bhandari S
Mini Rev Med Chem; 2022; 22(5):805-820. PubMed ID: 34477516
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
