These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 36777637)

  • 1. A new FRDA mouse model [
    Kalef-Ezra E; Edzeamey FJ; Valle A; Khonsari H; Kleine P; Oggianu C; Al-Mahdawi S; Pook MA; Anjomani Virmouni S
    Front Neurosci; 2023; 17():930422. PubMed ID: 36777637
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
    Anjomani Virmouni S; Ezzatizadeh V; Sandi C; Sandi M; Al-Mahdawi S; Chutake Y; Pook MA
    Dis Model Mech; 2015 Mar; 8(3):225-35. PubMed ID: 25681319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues.
    Al-Mahdawi S; Pinto RM; Ismail O; Varshney D; Lymperi S; Sandi C; Trabzuni D; Pook M
    Hum Mol Genet; 2008 Mar; 17(5):735-46. PubMed ID: 18045775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.
    Lufino MM; Silva AM; Németh AH; Alegre-Abarrategui J; Russell AJ; Wade-Martins R
    Hum Mol Genet; 2013 Dec; 22(25):5173-87. PubMed ID: 23943791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming.
    Polak U; Li Y; Butler JS; Napierala M
    Stem Cells Dev; 2016 Dec; 25(23):1788-1800. PubMed ID: 27615158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology.
    Al-Mahdawi S; Pinto RM; Varshney D; Lawrence L; Lowrie MB; Hughes S; Webster Z; Blake J; Cooper JM; King R; Pook MA
    Genomics; 2006 Nov; 88(5):580-90. PubMed ID: 16919418
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
    Anjomani Virmouni S; Sandi C; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(9):e107416. PubMed ID: 25198290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3.
    Chan PK; Torres R; Yandim C; Law PP; Khadayate S; Mauri M; Grosan C; Chapman-Rothe N; Giunti P; Pook M; Festenstein R
    Hum Mol Genet; 2013 Jul; 22(13):2662-75. PubMed ID: 23474817
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models.
    Sandi C; Sandi M; Jassal H; Ezzatizadeh V; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(2):e89488. PubMed ID: 24586819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Comprehensive Transcriptome Analysis Identifies FXN and BDNF as Novel Targets of miRNAs in Friedreich's Ataxia Patients.
    Misiorek JO; Schreiber AM; Urbanek-Trzeciak MO; Jazurek-Ciesiołka M; Hauser LA; Lynch DR; Napierala JS; Napierala M
    Mol Neurobiol; 2020 Jun; 57(6):2639-2653. PubMed ID: 32291635
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin.
    Fil D; Conley RL; Zuberi AR; Lutz CM; Gemelli T; Napierala M; Napierala JS
    Neurobiol Dis; 2023 Feb; 177():105996. PubMed ID: 36638893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.
    Li Y; Lu Y; Polak U; Lin K; Shen J; Farmer J; Seyer L; Bhalla AD; Rozwadowska N; Lynch DR; Butler JS; Napierala M
    Hum Mol Genet; 2015 Dec; 24(24):6932-43. PubMed ID: 26401053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation and characterization of iPSC lines from Friedreich's ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene's first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A).
    Ahmad I; Kamai A; Zahra S; Kapoor H; Kumar Srivastava A; Faruq M
    Stem Cell Res; 2024 Jun; 77():103382. PubMed ID: 38484450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus.
    Al-Mahdawi S; Sandi C; Mouro Pinto R; Pook MA
    PLoS One; 2013; 8(9):e74956. PubMed ID: 24023969
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy.
    Sandi C; Al-Mahdawi S; Pook MA
    Genet Res Int; 2013; 2013():852080. PubMed ID: 23533785
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers.
    Napierala JS; Li Y; Lu Y; Lin K; Hauser LA; Lynch DR; Napierala M
    Dis Model Mech; 2017 Nov; 10(11):1353-1369. PubMed ID: 29125828
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia.
    Kim E; Napierala M; Dent SY
    Nucleic Acids Res; 2011 Oct; 39(19):8366-77. PubMed ID: 21745819
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of two human induced pluripotent stem cell lines, IGIBi012-A and IGIBi013-A from Friedreich's ataxia (FRDA) patients with homozygous GAA repeat expansion in FXN gene.
    Ahmad I; Kapoor H; Srivastava AK; Faruq M
    Stem Cell Res; 2024 Apr; 76():103340. PubMed ID: 38367363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Somatic instability of the expanded GAA repeats in Friedreich's ataxia.
    Long A; Napierala JS; Polak U; Hauser L; Koeppen AH; Lynch DR; Napierala M
    PLoS One; 2017; 12(12):e0189990. PubMed ID: 29261783
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Generation and characterization of two human iPSC lines, IGIBi014-A and IGIBi015-A, from Friedreich's ataxia (FRDA) patients with pathogenic (GAA/TTC)n repeat expansion in first intron of the Frataxin (FXN) gene.
    Ahmad I; Kapoor H; Kumar Srivastava A; Faruq M
    Stem Cell Res; 2024 Feb; 74():103289. PubMed ID: 38141359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.