These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 36791209)

  • 21. The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-like receptor agonists.
    Vollmer S; Strickson S; Zhang T; Gray N; Lee KL; Rao VR; Cohen P
    Biochem J; 2017 Jun; 474(12):2027-2038. PubMed ID: 28512203
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapy.
    Baird AC; Mallon D; Radford-Smith G; Boyer J; Piche T; Prescott SL; Lawrance IC; Tulic MK
    World J Gastroenterol; 2016 Nov; 22(41):9104-9116. PubMed ID: 27895398
    [TBL] [Abstract][Full Text] [Related]  

  • 23. IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.
    Li Q; Chen Y; Zhang D; Grossman J; Li L; Khurana N; Jiang H; Grierson PM; Herndon J; DeNardo DG; Challen GA; Liu J; Ruzinova MB; Fields RC; Lim KH
    JCI Insight; 2019 Oct; 4(19):. PubMed ID: 31527315
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation.
    Fraczek J; Kim TW; Xiao H; Yao J; Wen Q; Li Y; Casanova JL; Pryjma J; Li X
    J Biol Chem; 2008 Nov; 283(46):31697-705. PubMed ID: 18794297
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4.
    Tumey LN; Boschelli DH; Bhagirath N; Shim J; Murphy EA; Goodwin D; Bennett EM; Wang M; Lin LL; Press B; Shen M; Frisbie RK; Morgan P; Mohan S; Shin J; Rao VR
    Bioorg Med Chem Lett; 2014 May; 24(9):2066-72. PubMed ID: 24726805
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
    Dudhgaonkar S; Ranade S; Nagar J; Subramani S; Prasad DS; Karunanithi P; Srivastava R; Venkatesh K; Selvam S; Krishnamurthy P; Mariappan TT; Saxena A; Fan L; Stetsko DK; Holloway DA; Li X; Zhu J; Yang WP; Ruepp S; Nair S; Santella J; Duncia J; Hynes J; McIntyre KW; Carman JA
    J Immunol; 2017 Feb; 198(3):1308-1319. PubMed ID: 28003376
    [TBL] [Abstract][Full Text] [Related]  

  • 27. IRAK4 Is Overexpressed in Hidradenitis Suppurativa Skin and Correlates with Inflammatory Biomarkers.
    McDonald A; Karnik R; Campbell V; Davis J; Chavoshi S; Slavin A; Sharma K; Gollob J; Alavi A
    J Invest Dermatol; 2024 Jul; ():. PubMed ID: 39084489
    [TBL] [Abstract][Full Text] [Related]  

  • 28. MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes.
    Rebane A; Runnel T; Aab A; Maslovskaja J; Rückert B; Zimmermann M; Plaas M; Kärner J; Treis A; Pihlap M; Haljasorg U; Hermann H; Nagy N; Kemeny L; Erm T; Kingo K; Li M; Boldin MP; Akdis CA
    J Allergy Clin Immunol; 2014 Oct; 134(4):836-847.e11. PubMed ID: 24996260
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis.
    Vandeghinste N; Klattig J; Jagerschmidt C; Lavazais S; Marsais F; Haas JD; Auberval M; Lauffer F; Moran T; Ongenaert M; Van Balen M; Dupont S; Lepescheux L; Garcia T; Härtle S; Eyerich K; Fallon PG; Brys R; Steidl S
    J Invest Dermatol; 2018 Jul; 138(7):1555-1563. PubMed ID: 29474945
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases.
    Wittmann M; Purwar R; Hartmann C; Gutzmer R; Werfel T
    J Invest Dermatol; 2005 Jun; 124(6):1225-33. PubMed ID: 15955098
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cloning and functional characterization of IRAK4 in large yellow croaker (Larimichthys crocea) that associates with MyD88 but impairs NF-κB activation.
    Zou PF; Huang XN; Yao CL; Sun QX; Li Y; Zhu Q; Yu ZX; Fan ZJ
    Fish Shellfish Immunol; 2017 Apr; 63():452-464. PubMed ID: 27989863
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.
    Loiarro M; Capolunghi F; Fantò N; Gallo G; Campo S; Arseni B; Carsetti R; Carminati P; De Santis R; Ruggiero V; Sette C
    J Leukoc Biol; 2007 Oct; 82(4):801-10. PubMed ID: 17548806
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitors: an updated patent review (2016-2018).
    McElroy WT
    Expert Opin Ther Pat; 2019 Apr; 29(4):243-259. PubMed ID: 30916602
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.
    Béla SR; Dutra MS; Mui E; Montpetit A; Oliveira FS; Oliveira SC; Arantes RM; Antonelli LR; McLeod R; Gazzinelli RT
    Infect Immun; 2012 Dec; 80(12):4298-308. PubMed ID: 23027530
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Clinical IRAK4 deficiency caused by homozygosity for the novel
    Jia A; James E; Lu HY; Sharma M; Modi BP; Biggs CM; Hildebrand KJ; Chomyn A; Erdle S; Kular H; Turvey SE
    Cold Spring Harb Mol Case Stud; 2020 Jun; 6(3):. PubMed ID: 32532880
    [TBL] [Abstract][Full Text] [Related]  

  • 36. IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop.
    Hashiguchi Y; Yabe R; Chung SH; Murayama MA; Yoshida K; Matsuo K; Kubo S; Saijo S; Nakamura Y; Matsue H; Iwakura Y
    J Immunol; 2018 Jul; 201(1):167-182. PubMed ID: 29794016
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.
    Lin SC; Lo YC; Wu H
    Nature; 2010 Jun; 465(7300):885-90. PubMed ID: 20485341
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia.
    Giménez N; Schulz R; Higashi M; Aymerich M; Villamor N; Delgado J; Juan M; López-Guerra M; Campo E; Rosich L; Seiffert M; Colomer D
    Leukemia; 2020 Jan; 34(1):100-114. PubMed ID: 31197259
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effect of γ-secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis-like skin inflammation.
    Ma L; Xue H; Qi R; Wang Y; Yuan L
    J Transl Med; 2018 Mar; 16(1):59. PubMed ID: 29523162
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Small Molecule Inhibition of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4).
    Genung NE; Guckian KM
    Prog Med Chem; 2017; 56():117-163. PubMed ID: 28314411
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.