These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 36797043)

  • 1. AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
    Asteriti IA; Polverino F; Stagni V; Sterbini V; Ascanelli C; Naso FD; Mastrangelo A; Rosa A; Paiardini A; Lindon C; Guarguaglini G
    Life Sci Alliance; 2023 May; 6(5):. PubMed ID: 36797043
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway.
    Naso FD; Polverino F; Cilluffo D; Latini L; Stagni V; Asteriti IA; Rosa A; Soddu S; Guarguaglini G
    Biochim Biophys Acta Mol Basis Dis; 2024 Apr; 1870(4):167116. PubMed ID: 38447882
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.
    Takahashi Y; Sheridan P; Niida A; Sawada G; Uchi R; Mizuno H; Kurashige J; Sugimachi K; Sasaki S; Shimada Y; Hase K; Kusunoki M; Kudo S; Watanabe M; Yamada K; Sugihara K; Yamamoto H; Suzuki A; Doki Y; Miyano S; Mori M; Mimori K
    Ann Oncol; 2015 May; 26(5):935-942. PubMed ID: 25632068
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.
    Polverino F; Mastrangelo A; Guarguaglini G
    Cells; 2024 Aug; 13(16):. PubMed ID: 39195284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bcl2l10, a new Tpx2 binding partner, is a master regulator of Aurora kinase A in mouse oocytes.
    Lee SY; Kim EY; Kim KH; Lee KA
    Cell Cycle; 2016 Dec; 15(23):3296-3305. PubMed ID: 27753540
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Taxane-mediated radiosensitization derives from chromosomal missegregation on tripolar mitotic spindles orchestrated by AURKA and TPX2.
    Orth M; Unger K; Schoetz U; Belka C; Lauber K
    Oncogene; 2018 Jan; 37(1):52-62. PubMed ID: 28869599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
    Janeček M; Rossmann M; Sharma P; Emery A; Huggins DJ; Stockwell SR; Stokes JE; Tan YS; Almeida EG; Hardwick B; Narvaez AJ; Hyvönen M; Spring DR; McKenzie GJ; Venkitaraman AR
    Sci Rep; 2016 Jun; 6():28528. PubMed ID: 27339427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aurora A kinase and its activator TPX2 are potential therapeutic targets in KRAS-induced pancreatic cancer.
    Gomes-Filho SM; Dos Santos EO; Bertoldi ERM; Scalabrini LC; Heidrich V; Dazzani B; Levantini E; Reis EM; Bassères DS
    Cell Oncol (Dordr); 2020 Jun; 43(3):445-460. PubMed ID: 32193808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.
    Lim NR; Yeap YY; Ang CS; Williamson NA; Bogoyevitch MA; Quinn LM; Ng DC
    Cell Cycle; 2016; 15(3):413-24. PubMed ID: 26713495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.
    Li L; Yang G; Ren C; Tanimoto R; Hirayama T; Wang J; Hawke D; Kim SM; Lee JS; Goltsov AA; Park S; Ittmann MM; Troncoso P; Thompson TC
    Mol Oncol; 2013 Jun; 7(3):484-96. PubMed ID: 23333597
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AURKA destruction is decoupled from its activity at mitotic exit but is essential to suppress interphase activity.
    Abdelbaki A; Akman HB; Poteau M; Grant R; Gavet O; Guarguaglini G; Lindon C
    J Cell Sci; 2020 Jun; 133(12):. PubMed ID: 32393600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Control of Aurora-A stability through interaction with TPX2.
    Giubettini M; Asteriti IA; Scrofani J; De Luca M; Lindon C; Lavia P; Guarguaglini G
    J Cell Sci; 2011 Jan; 124(Pt 1):113-22. PubMed ID: 21147853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unveiling Potential Targeted Therapeutic Opportunities for Co-Overexpressed Targeting Protein for Xklp2 and Aurora-A Kinase in Lung Adenocarcinoma.
    Mukherjee A; Yadav PH; Mukunthan KS
    Mol Biotechnol; 2024 Oct; 66(10):2792-2803. PubMed ID: 37768502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2.
    Chen H; Mohan P; Jiang J; Nemirovsky O; He D; Fleisch MC; Niederacher D; Pilarski LM; Lim CJ; Maxwell CA
    Cell Cycle; 2014; 13(14):2248-61. PubMed ID: 24875404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TPX2 deficiency leads to spindle abnormity and meiotic impairment in porcine oocytes.
    He Y; Peng L; Li J; Li Q; Chu Y; Lin Q; Rui R; Ju S
    Theriogenology; 2022 Jul; 187():164-172. PubMed ID: 35576634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TPX2 overexpression in medullary thyroid carcinoma mediates TT cell proliferation.
    Yang X; Liu G; Xiao H; Yu F; Xiang X; Lu Y; Li W; Liu X; Li S; Shi Y
    Pathol Oncol Res; 2014 Jul; 20(3):641-8. PubMed ID: 24488334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.
    Naso FD; Sterbini V; Crecca E; Asteriti IA; Russo AD; Giubettini M; Cundari E; Lindon C; Rosa A; Guarguaglini G
    Cells; 2020 Feb; 9(2):. PubMed ID: 32041138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioinformatics and experimental validation of an AURKA/TPX2 axis as a potential target in esophageal squamous cell carcinoma.
    Du R; Li K; Zhou Z; Huang Y; Guo K; Zhang H; Chen Z; Zhao X; Han L; Bian H
    Oncol Rep; 2023 Jun; 49(6):. PubMed ID: 37083097
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for the design of allosteric inhibitors of the Aurora kinase A enzyme in the cancer chemotherapy.
    de Souza VB; Kawano DF
    Biochim Biophys Acta Gen Subj; 2020 Jan; 1864(1):129448. PubMed ID: 31676293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation.
    Lin CC; Kitagawa M; Tang X; Hou MH; Wu J; Qu DC; Srinivas V; Liu X; Thompson JW; Mathey-Prevot B; Yao TP; Lee SH; Chi JT
    Nat Commun; 2018 Mar; 9(1):1039. PubMed ID: 29531224
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.