BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 36798479)

  • 1. Comparative Pharmacology of a Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor of Enolase after Oral and Parenteral Administration.
    Yan VC; Barekatain Y; Lin YH; Satani N; Hammoudi N; Arthur K; Georgiou DK; Jiang Y; Sun Y; Marszalek JR; Millward SW; Muller FL
    ACS Pharmacol Transl Sci; 2023 Feb; 6(2):245-252. PubMed ID: 36798479
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of
    Yan VC; Pham CD; Ballato ES; Yang KL; Arthur K; Khadka S; Barekatain Y; Shrestha P; Tran T; Poral AH; Washington M; Raghavan S; Czako B; Pisaneschi F; Lin YH; Satani N; Hammoudi N; Ackroyd JJ; Georgiou DK; Millward SW; Muller FL
    J Med Chem; 2022 Oct; 65(20):13813-13832. PubMed ID: 36251833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine.
    Naesens L; Balzarini J; Bischofberger N; De Clercq E
    Antimicrob Agents Chemother; 1996 Jan; 40(1):22-8. PubMed ID: 8787873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2).
    Annaert P; Kinget R; Naesens L; de Clercq E; Augustijns P
    Pharm Res; 1997 Apr; 14(4):492-6. PubMed ID: 9144737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma.
    Khadka S; Arthur K; Barekatain Y; Behr E; Washington M; Ackroyd J; Crowley K; Suriyamongkol P; Lin YH; Pham CD; Zielinski R; Trujillo M; Galligan J; Georgiou DK; Asara J; Muller F
    Cancer Metab; 2021 Jun; 9(1):27. PubMed ID: 34172075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of the disposition of ester prodrugs of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 monolayers.
    Annaert P; Gosselin G; Pompon A; Benzaria S; Valette G; Imbach JL; Naesens L; Hatse S; de Clercq E; Van den Mooter G; Kinget R; Augustijns P
    Pharm Res; 1998 Feb; 15(2):239-45. PubMed ID: 9523310
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enolase Inhibitors as Early Lead Therapeutics against
    Roster CP; LaVigne D; Milanes JE; Knight E; Anderson HD; Pizarro S; Harding EM; Morris MT; Yan VC; Pham CD; Muller F; Kwain S; Rees KC; Dominy B; Whitehead DC; Uddin MN; Millward SW; Morris JC
    Pathogens; 2023 Oct; 12(11):. PubMed ID: 38003754
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism and pharmacokinetics of novel oral prodrugs of 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.
    Shaw JP; Sueoko CM; Oliyai R; Lee WA; Arimilli MN; Kim CU; Cundy KC
    Pharm Res; 1997 Dec; 14(12):1824-9. PubMed ID: 9453075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue.
    Gupta D; Varghese Gupta S; Dahan A; Tsume Y; Hilfinger J; Lee KD; Amidon GL
    Mol Pharm; 2013 Feb; 10(2):512-22. PubMed ID: 23244438
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of Orally Available Prodrugs of the Glutamate Carboxypeptidase II (GCPII) Inhibitor 2-Phosphonomethylpentanedioic Acid (2-PMPA).
    Majer P; Jančařík A; Krečmerová M; Tichý T; Tenora L; Wozniak K; Wu Y; Pommier E; Ferraris D; Rais R; Slusher BS
    J Med Chem; 2016 Mar; 59(6):2810-9. PubMed ID: 26930119
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine.
    Starrett JE; Tortolani DR; Hitchcock MJ; Martin JC; Mansuri MM
    Antiviral Res; 1992 Sep; 19(3):267-73. PubMed ID: 1332606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
    Schumacher-Klinger A; Fanous J; Merzbach S; Weinmüller M; Reichart F; Räder AFB; Gitlin-Domagalska A; Gilon C; Kessler H; Hoffman A
    Mol Pharm; 2018 Aug; 15(8):3468-3477. PubMed ID: 29976060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
    Prueksaritanont T; Gorham LM; Breslin MJ; Hutchinson JH; Hartman GD; Vyas KP; Baillie TA
    Drug Metab Dispos; 1997 Aug; 25(8):978-84. PubMed ID: 9280406
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of metabolite kinetics by deconvolution and in vivo-in vitro correlations of metabolite formation rates: studies of fibrinogen receptor antagonist ester prodrugs.
    Prueksaritanont T; Gorham LM; Yeh KC
    J Pharm Sci; 1997 Dec; 86(12):1345-51. PubMed ID: 9423143
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects.
    Krečmerová M; Majer P; Rais R; Slusher BS
    Front Chem; 2022; 10():889737. PubMed ID: 35668826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics of bis(t-butyl-SATE)-AZTMP, a bispivaloylthioethyl prodrug for intracellular delivery of zidovudine monophosphate, in mice.
    Tan X; Boudinot FD; Chu CK; Egron D; Perigaud C; Gosselin G; Imbach JL
    Antivir Chem Chemother; 2000 May; 11(3):203-11. PubMed ID: 10901291
    [TBL] [Abstract][Full Text] [Related]  

  • 17. L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery.
    Puris E; Gynther M; Huttunen J; Auriola S; Huttunen KM
    Eur J Pharm Sci; 2019 Mar; 129():99-109. PubMed ID: 30625368
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxicity of pivoxil esters of antiviral acyclic nucleoside phosphonates: adefovir dipivoxil versus adefovir.
    Zídek Z; Kmonícková E; Holý A
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Dec; 149(2):315-9. PubMed ID: 16601779
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach.
    Qin C; Chu Y; Feng W; Fromont C; He S; Ali J; Lee JB; Zgair A; Berton M; Bettonte S; Liu R; Yang L; Monmaturapoj T; Medrano-Padial C; Ugalde AAR; Vetrugno D; Ee SY; Sheriston C; Wu Y; Stocks MJ; Fischer PM; Gershkovich P
    J Control Release; 2021 Jan; 329():1077-1089. PubMed ID: 33091528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Efficiency of bis-amidate phosphonate prodrugs.
    Lentini NA; Huang X; Schladetsch MA; Hsiao CC; Wiemer DF; Wiemer AJ
    Bioorg Med Chem Lett; 2022 Jun; 66():128724. PubMed ID: 35405283
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.