BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 36803256)

  • 1. PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells.
    Roy A; Chakraborty AR; Nomanbhoy T; DePamphilis ML
    Autophagy; 2023 Sep; 19(9):2464-2484. PubMed ID: 36803256
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
    Sharma G; Guardia CM; Roy A; Vassilev A; Saric A; Griner LN; Marugan J; Ferrer M; Bonifacino JS; DePamphilis ML
    Autophagy; 2019 Oct; 15(10):1694-1718. PubMed ID: 30806145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequential conversion of PtdIns3P to PtdIns(3,5)P
    Rodgers SJ; Jones EI; Mitchell CA; McGrath MJ
    Autophagy; 2023 Apr; 19(4):1365-1367. PubMed ID: 36103410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
    Fernandez-Mosquera L; Yambire KF; Couto R; Pereyra L; Pabis K; Ponsford AH; Diogo CV; Stagi M; Milosevic I; Raimundo N
    Autophagy; 2019 Sep; 15(9):1572-1591. PubMed ID: 30917721
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential regulation by phosphatidylinositol 4,5-bisphosphate of pituitary plasma-membrane and cytosolic phosphoinositide kinases.
    Imai A; Rebecchi MJ; Gershengorn MC
    Biochem J; 1986 Dec; 240(2):341-8. PubMed ID: 3028374
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation.
    Sbrissa D; Naisan G; Ikonomov OC; Shisheva A
    PLoS One; 2018; 13(9):e0204532. PubMed ID: 30240452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.
    Ikonomov OC; Sbrissa D; Venkatareddy M; Tisdale E; Garg P; Shisheva A
    Biochim Biophys Acta; 2015 May; 1853(5):1240-50. PubMed ID: 25619930
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
    Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
    Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells.
    Gold MR; Aebersold R
    J Immunol; 1994 Jan; 152(1):42-50. PubMed ID: 8254204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).
    Shisheva A; Sbrissa D; Ikonomov O
    Bioessays; 2015 Mar; 37(3):267-77. PubMed ID: 25404370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.
    Ikonomov OC; Filios C; Sbrissa D; Chen X; Shisheva A
    Biochem Biophys Res Commun; 2013 Oct; 440(2):342-7. PubMed ID: 24070605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
    Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
    Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases.
    Rodgers SJ; Ferguson DT; Mitchell CA; Ooms LM
    Biosci Rep; 2017 Feb; 37(1):. PubMed ID: 28082369
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of phosphoinositide-3-kinase by G protein beta gamma subunits in a rat osteosarcoma cell line.
    Morris AJ; Rudge SA; Mahlum CE; Jenco JM
    Mol Pharmacol; 1995 Sep; 48(3):532-9. PubMed ID: 7565635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
    Saffi GT; Wang CA; Mangialardi EM; Vacher J; Botelho RJ; Salmena L
    J Biol Chem; 2022 Aug; 298(8):102187. PubMed ID: 35760104
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity.
    Lu PJ; Shieh WR; Rhee SG; Yin HL; Chen CS
    Biochemistry; 1996 Nov; 35(44):14027-34. PubMed ID: 8909300
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
    Sbrissa D; Ikonomov OC; Fu Z; Ijuin T; Gruenberg J; Takenawa T; Shisheva A
    J Biol Chem; 2007 Aug; 282(33):23878-91. PubMed ID: 17556371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P
    Eramo MJ; Gurung R; Mitchell CA; McGrath MJ
    Autophagy; 2021 May; 17(5):1287-1289. PubMed ID: 33879025
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.
    Ho CY; Choy CH; Wattson CA; Johnson DE; Botelho RJ
    J Biol Chem; 2015 Apr; 290(15):9919-28. PubMed ID: 25713145
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions.
    Caux M; Mansour R; Xuereb JM; Chicanne G; Viaud J; Vauclard A; Boal F; Payrastre B; Tronchère H; Severin S
    Arterioscler Thromb Vasc Biol; 2022 Aug; 42(8):987-1004. PubMed ID: 35708031
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.