179 related articles for article (PubMed ID: 36823378)
1. HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer.
Liu B; Zhang J; Meng X; Xie SM; Liu F; Chen H; Yao D; Li M; Guo M; Shen H; Zhang X; Xing L
Oncogene; 2023 Apr; 42(15):1181-1195. PubMed ID: 36823378
[TBL] [Abstract][Full Text] [Related]
2. G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT; Rehbein U; Cadena Sandoval M; De Meulemeester AS; Baumeister R; Brohée L; Berdel B; Bockwoldt M; Carroll B; Chowdhury SR; von Deimling A; Demetriades C; Figlia G; ; de Araujo MEG; Heberle AM; Heiland I; Holzwarth B; Huber LA; Jaworski J; Kedra M; Kern K; Kopach A; Korolchuk VI; van 't Land-Kuper I; Macias M; Nellist M; Palm W; Pusch S; Ramos Pittol JM; Reil M; Reintjes A; Reuter F; Sampson JR; Scheldeman C; Siekierska A; Stefan E; Teleman AA; Thomas LE; Torres-Quesada O; Trump S; West HD; de Witte P; Woltering S; Yordanov TE; Zmorzynska J; Opitz CA; Thedieck K
Cell; 2021 Feb; 184(3):655-674.e27. PubMed ID: 33497611
[TBL] [Abstract][Full Text] [Related]
3. Amino Acid-Mediated Intracellular Ca
Amemiya Y; Nakamura N; Ikeda N; Sugiyama R; Ishii C; Maki M; Shibata H; Takahara T
Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34198993
[TBL] [Abstract][Full Text] [Related]
4. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
Lin Y; Henderson P; Pettersson S; Satsangi J; Hupp T; Stevens C
FEBS J; 2011 Jan; 278(2):354-70. PubMed ID: 21134130
[TBL] [Abstract][Full Text] [Related]
5. Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells.
Li C; Liu X; Liu Y; Zhang E; Medepalli K; Masuda K; Li N; Wikenheiser-Brokamp KA; Osterburg A; Borchers MT; Kopras EJ; Plas DR; Sun J; Franz DN; Capal JK; Mays M; Sun Y; Kwiatkowski DJ; Alayev A; Holz MK; Krueger DA; Siroky BJ; Yu JJ
Mol Cancer Res; 2017 Oct; 15(10):1318-1330. PubMed ID: 28710231
[TBL] [Abstract][Full Text] [Related]
6. MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer.
Li H; Lin PH; Gupta P; Li X; Zhao SL; Zhou X; Li Z; Wei S; Xu L; Han R; Lu J; Tan T; Yang DH; Chen ZS; Pawlik TM; Merritt RE; Ma J
Mol Cancer; 2021 Sep; 20(1):118. PubMed ID: 34521423
[TBL] [Abstract][Full Text] [Related]
7. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.
Dong P; Wang X; Liu L; Tang W; Ma L; Zeng W; Sun S; Zhang L; Zhang N; Shen X; Janssen HLA; Dong L; Zhang S; Chen S
J Hepatol; 2020 Dec; 73(6):1446-1459. PubMed ID: 32610114
[TBL] [Abstract][Full Text] [Related]
8. Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production.
Byun JK; Park M; Yun JW; Lee J; Kim JS; Cho SJ; Lee YM; Lee IK; Choi YK; Park KG
EMBO Rep; 2019 Jun; 20(6):. PubMed ID: 30988000
[TBL] [Abstract][Full Text] [Related]
9. Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells.
Chen W; Pan Y; Wang S; Liu Y; Chen G; Zhou L; Ni W; Wang A; Lu Y
BMC Cancer; 2017 Jan; 17(1):34. PubMed ID: 28061838
[TBL] [Abstract][Full Text] [Related]
10. Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids.
Frias MA; Mukhopadhyay S; Lehman E; Walasek A; Utter M; Menon D; Foster DA
J Biol Chem; 2020 Jan; 295(1):263-274. PubMed ID: 31767684
[TBL] [Abstract][Full Text] [Related]
11. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.
Agarwal S; Bell CM; Taylor SM; Moran RG
Mol Cancer Res; 2016 Jan; 14(1):66-77. PubMed ID: 26385560
[TBL] [Abstract][Full Text] [Related]
12. Lysosomal recruitment of TSC2 is a universal response to cellular stress.
Demetriades C; Plescher M; Teleman AA
Nat Commun; 2016 Feb; 7():10662. PubMed ID: 26868506
[TBL] [Abstract][Full Text] [Related]
13. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
[TBL] [Abstract][Full Text] [Related]
14. Phosphorylation of TSC2 by PKC-δ reveals a novel signaling pathway that couples protein synthesis to mTORC1 activity.
Zhan J; Chitta RK; Harwood FC; Grosveld GC
Mol Cell Biochem; 2019 Jun; 456(1-2):123-134. PubMed ID: 30684133
[TBL] [Abstract][Full Text] [Related]
15. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
Jiang S; Zou Z; Nie P; Wen R; Xiao Y; Tang J
PLoS One; 2015; 10(7):e0132880. PubMed ID: 26176608
[TBL] [Abstract][Full Text] [Related]
16. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
17. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
[TBL] [Abstract][Full Text] [Related]
18. Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
Stepanova V; Dergilev KV; Holman KR; Parfyonova YV; Tsokolaeva ZI; Teter M; Atochina-Vasserman EN; Volgina A; Zaitsev SV; Lewis SP; Zabozlaev FG; Obraztsova K; Krymskaya VP; Cines DB
J Biol Chem; 2017 Dec; 292(50):20528-20543. PubMed ID: 28972182
[TBL] [Abstract][Full Text] [Related]
19. MTORC1-Regulated Metabolism Controlled by TSC2 Limits Cardiac Reperfusion Injury.
Oeing CU; Jun S; Mishra S; Dunkerly-Eyring BL; Chen A; Grajeda MI; Tahir UA; Gerszten RE; Paolocci N; Ranek MJ; Kass DA
Circ Res; 2021 Mar; 128(5):639-651. PubMed ID: 33401933
[TBL] [Abstract][Full Text] [Related]
20. mTORC2 is required for proliferation and survival of TSC2-null cells.
Goncharova EA; Goncharov DA; Li H; Pimtong W; Lu S; Khavin I; Krymskaya VP
Mol Cell Biol; 2011 Jun; 31(12):2484-98. PubMed ID: 21482669
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
