142 related articles for article (PubMed ID: 36841139)
1. A novel gain of function mutation in TPC2 reiterates pH-pigmentation interplay: Emerging role of ionic homeostasis as a master pigmentation regulator.
Sharma N; Sharma A; Motiani RK
Cell Calcium; 2023 May; 111():102705. PubMed ID: 36841139
[TBL] [Abstract][Full Text] [Related]
2. A gain-of-function TPC2 variant R210C increases affinity to PI(3,5)P
Wang Q; Wang Z; Wang Y; Qi Z; Bai D; Wang C; Chen Y; Xu W; Zhu X; Jeon J; Xiong J; Hao C; Zhu MX; Wei A; Li W
Nat Commun; 2023 Jan; 14(1):226. PubMed ID: 36641477
[TBL] [Abstract][Full Text] [Related]
3. TPC2 controls pigmentation by regulating melanosome pH and size.
Ambrosio AL; Boyle JA; Aradi AE; Christian KA; Di Pietro SM
Proc Natl Acad Sci U S A; 2016 May; 113(20):5622-7. PubMed ID: 27140606
[TBL] [Abstract][Full Text] [Related]
4. A melanosomal two-pore sodium channel regulates pigmentation.
Bellono NW; Escobar IE; Oancea E
Sci Rep; 2016 May; 6():26570. PubMed ID: 27231233
[TBL] [Abstract][Full Text] [Related]
5. Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect.
Böck J; Krogsaeter E; Passon M; Chao YK; Sharma S; Grallert H; Peters A; Grimm C
PLoS Genet; 2021 Jan; 17(1):e1009236. PubMed ID: 33465068
[TBL] [Abstract][Full Text] [Related]
6. An intracellular anion channel critical for pigmentation.
Bellono NW; Escobar IE; Lefkovith AJ; Marks MS; Oancea E
Elife; 2014 Dec; 3():e04543. PubMed ID: 25513726
[TBL] [Abstract][Full Text] [Related]
7. Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Gerndt S; Chen CC; Chao YK; Yuan Y; Burgstaller S; Scotto Rosato A; Krogsaeter E; Urban N; Jacob K; Nguyen ONP; Miller MT; Keller M; Vollmar AM; Gudermann T; Zierler S; Schredelseker J; Schaefer M; Biel M; Malli R; Wahl-Schott C; Bracher F; Patel S; Grimm C
Elife; 2020 Mar; 9():. PubMed ID: 32167471
[TBL] [Abstract][Full Text] [Related]
8. Two-pore channel 2 is required for soluble adenylyl cyclase-dependent regulation of melanosomal pH and melanin synthesis.
Zhou D; Eraslan Z; Miller D; Taylor I; You J; Grondin SJ; Vega M; Manga P; Goff PS; Sviderskaya EV; Gross SS; Chen Q; Zippin JH
Pigment Cell Melanoma Res; 2024 Jun; ():. PubMed ID: 38844435
[TBL] [Abstract][Full Text] [Related]
9. TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.
Chao YK; Schludi V; Chen CC; Butz E; Nguyen ONP; Müller M; Krüger J; Kammerbauer C; Ben-Johny M; Vollmar AM; Berking C; Biel M; Wahl-Schott CA; Grimm C
Proc Natl Acad Sci U S A; 2017 Oct; 114(41):E8595-E8602. PubMed ID: 28923947
[TBL] [Abstract][Full Text] [Related]
10. Membrane transport proteins in melanosomes: Regulation of ions for pigmentation.
Wiriyasermkul P; Moriyama S; Nagamori S
Biochim Biophys Acta Biomembr; 2020 Dec; 1862(12):183318. PubMed ID: 32333855
[TBL] [Abstract][Full Text] [Related]
11. Single organelle measurements of melanosome pH using the novel ratiometric indicator RpHiMEL.
Scales JL; Koroma DC; Oancea E
Methods Enzymol; 2021; 654():315-344. PubMed ID: 34120720
[TBL] [Abstract][Full Text] [Related]
12. TRPA1 promotes UVB-induced skin pigmentation by regulating melanosome luminal pH.
Wu W; Wang Y; Liu Y; Guo H; Li Z; Zou W; Liu J; Song Z
Exp Dermatol; 2023 Feb; 32(2):165-176. PubMed ID: 36302111
[TBL] [Abstract][Full Text] [Related]
13. Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.
Lin PH; Duann P; Komazaki S; Park KH; Li H; Sun M; Sermersheim M; Gumpper K; Parrington J; Galione A; Evans AM; Zhu MX; Ma J
J Biol Chem; 2015 Feb; 290(6):3377-89. PubMed ID: 25480788
[TBL] [Abstract][Full Text] [Related]
14. Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH.
Lu Y; Hao BX; Graeff R; Wong CW; Wu WT; Yue J
J Biol Chem; 2013 Aug; 288(33):24247-63. PubMed ID: 23836916
[TBL] [Abstract][Full Text] [Related]
15. The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation.
Lin-Moshier Y; Keebler MV; Hooper R; Boulware MJ; Liu X; Churamani D; Abood ME; Walseth TF; Brailoiu E; Patel S; Marchant JS
Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13087-92. PubMed ID: 25157141
[TBL] [Abstract][Full Text] [Related]
16. {alpha}MSH and Cyclic AMP elevating agents control melanosome pH through a protein kinase A-independent mechanism.
Cheli Y; Luciani F; Khaled M; Beuret L; Bille K; Gounon P; Ortonne JP; Bertolotto C; Ballotti R
J Biol Chem; 2009 Jul; 284(28):18699-706. PubMed ID: 19389708
[TBL] [Abstract][Full Text] [Related]
17. The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH.
Brilliant MH
Pigment Cell Res; 2001 Apr; 14(2):86-93. PubMed ID: 11310796
[TBL] [Abstract][Full Text] [Related]
18. Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells.
Sirés-Campos J; Lambertos A; Delevoye C; Raposo G; Bennett DC; Sviderskaya E; Jiménez-Cervantes C; Olivares C; García-Borrón JC
Cell Mol Life Sci; 2021 Dec; 79(1):47. PubMed ID: 34921635
[TBL] [Abstract][Full Text] [Related]
19. Targeting TPC2 sensitizes acute lymphoblastic leukemia cells to chemotherapeutics by impairing lysosomal function.
Geisslinger F; Müller M; Chao YK; Grimm C; Vollmar AM; Bartel K
Cell Death Dis; 2022 Aug; 13(8):668. PubMed ID: 35915060
[TBL] [Abstract][Full Text] [Related]
20. Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells.
Ancans J; Tobin DJ; Hoogduijn MJ; Smit NP; Wakamatsu K; Thody AJ
Exp Cell Res; 2001 Aug; 268(1):26-35. PubMed ID: 11461115
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
