These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 36847506)

  • 21. Targeting Isocitrate Dehydrogenase Mutations in Cancer: Emerging Evidence and Diverging Strategies.
    Waitkus MS; Yan H
    Clin Cancer Res; 2021 Jan; 27(2):383-388. PubMed ID: 32883741
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.
    Guilhamon P; Eskandarpour M; Halai D; Wilson GA; Feber A; Teschendorff AE; Gomez V; Hergovich A; Tirabosco R; Fernanda Amary M; Baumhoer D; Jundt G; Ross MT; Flanagan AM; Beck S
    Nat Commun; 2013; 4():2166. PubMed ID: 23863747
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.
    Ward PS; Cross JR; Lu C; Weigert O; Abel-Wahab O; Levine RL; Weinstock DM; Sharp KA; Thompson CB
    Oncogene; 2012 May; 31(19):2491-8. PubMed ID: 21996744
    [TBL] [Abstract][Full Text] [Related]  

  • 24. IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition.
    Kernytsky A; Wang F; Hansen E; Schalm S; Straley K; Gliser C; Yang H; Travins J; Murray S; Dorsch M; Agresta S; Schenkein DP; Biller SA; Su SM; Liu W; Yen KE
    Blood; 2015 Jan; 125(2):296-303. PubMed ID: 25398940
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Intraoperative assessment of isocitrate dehydrogenase mutation status in human gliomas using desorption electrospray ionization-mass spectrometry.
    Alfaro CM; Pirro V; Keating MF; Hattab EM; Cooks RG; Cohen-Gadol AA
    J Neurosurg; 2020 Jan; 132(1):180-187. PubMed ID: 30611146
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma.
    Chuntova P; Yamamichi A; Chen T; Narayanaswamy R; Ronseaux S; Hudson C; Tron AE; Hyer ML; Montoya M; Mende AL; Nejo T; Downey KM; Diebold D; Lu M; Nicolay B; Okada H
    J Immunother Cancer; 2022 May; 10(5):. PubMed ID: 35606087
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.
    Koivunen P; Lee S; Duncan CG; Lopez G; Lu G; Ramkissoon S; Losman JA; Joensuu P; Bergmann U; Gross S; Travins J; Weiss S; Looper R; Ligon KL; Verhaak RG; Yan H; Kaelin WG
    Nature; 2012 Feb; 483(7390):484-8. PubMed ID: 22343896
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition.
    Chen C; Liu Y; Lu C; Cross JR; Morris JP; Shroff AS; Ward PS; Bradner JE; Thompson C; Lowe SW
    Genes Dev; 2013 Sep; 27(18):1974-85. PubMed ID: 24065765
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor.
    Elhammali A; Ippolito JE; Collins L; Crowley J; Marasa J; Piwnica-Worms D
    Cancer Discov; 2014 Jul; 4(7):828-39. PubMed ID: 24740997
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Biological Significance of Mutant Isocitrate Dehydrogenase 1 and 2 in Gliomagenesis.
    Ohba S; Hirose Y
    Neurol Med Chir (Tokyo); 2016; 56(4):170-9. PubMed ID: 26960449
    [TBL] [Abstract][Full Text] [Related]  

  • 31. 2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations.
    Jin G; Reitman ZJ; Spasojevic I; Batinic-Haberle I; Yang J; Schmidt-Kittler O; Bigner DD; Yan H
    PLoS One; 2011 Feb; 6(2):e16812. PubMed ID: 21326614
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The role of IDH mutations in acute myeloid leukemia.
    Montalban-Bravo G; DiNardo CD
    Future Oncol; 2018 Apr; 14(10):979-993. PubMed ID: 29543066
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Isocitrate dehydrogenase 1 and 2 mutations, 2-hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia.
    Brunner AM; Neuberg DS; Wander SA; Sadrzadeh H; Ballen KK; Amrein PC; Attar E; Hobbs GS; Chen YB; Perry A; Connolly C; Joseph C; Burke M; Ramos A; Galinsky I; Yen K; Yang H; Straley K; Agresta S; Adamia S; Borger DR; Iafrate A; Graubert TA; Stone RM; Fathi AT
    Cancer; 2019 Feb; 125(4):541-549. PubMed ID: 30422308
    [TBL] [Abstract][Full Text] [Related]  

  • 34. IDH1 p.R132H ctDNA and D-2-hydroxyglutarate as CSF biomarkers in patients with IDH-mutant gliomas.
    Fujita Y; Nunez-Rubiano L; Dono A; Bellman A; Shah M; Rodriguez JC; Putluri V; Kamal AHM; Putluri N; Riascos RF; Zhu JJ; Esquenazi Y; Ballester LY
    J Neurooncol; 2022 Sep; 159(2):261-270. PubMed ID: 35816267
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 2-Hydroxyglutarate in Cancer Cells.
    Ježek P
    Antioxid Redox Signal; 2020 Nov; 33(13):903-926. PubMed ID: 31847543
    [No Abstract]   [Full Text] [Related]  

  • 36. 2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation.
    Schvartzman JM; Reuter VP; Koche RP; Thompson CB
    Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12851-12856. PubMed ID: 31182575
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.
    Sulkowski PL; Corso CD; Robinson ND; Scanlon SE; Purshouse KR; Bai H; Liu Y; Sundaram RK; Hegan DC; Fons NR; Breuer GA; Song Y; Mishra-Gorur K; De Feyter HM; de Graaf RA; Surovtseva YV; Kachman M; Halene S; Günel M; Glazer PM; Bindra RS
    Sci Transl Med; 2017 Feb; 9(375):. PubMed ID: 28148839
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Increased plasma d-2-hydroxyglutarate in isocitrate dehydrogenase 2-mutated blastic plasmacytoid dendritic cell neoplasm.
    Rakheja D; Fuda F; Vandergriff T; Boriack R; Medeiros BC; Frankel AE; Chen W
    Hum Pathol; 2015 Feb; 46(2):322-6. PubMed ID: 25481493
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells.
    Smolková K; Dvořák A; Zelenka J; Vítek L; Ježek P
    Int J Biochem Cell Biol; 2015 Aug; 65():125-33. PubMed ID: 26007236
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.
    McBrayer SK; Mayers JR; DiNatale GJ; Shi DD; Khanal J; Chakraborty AA; Sarosiek KA; Briggs KJ; Robbins AK; Sewastianik T; Shareef SJ; Olenchock BA; Parker SJ; Tateishi K; Spinelli JB; Islam M; Haigis MC; Looper RE; Ligon KL; Bernstein BE; Carrasco RD; Cahill DP; Asara JM; Metallo CM; Yennawar NH; Vander Heiden MG; Kaelin WG
    Cell; 2018 Sep; 175(1):101-116.e25. PubMed ID: 30220459
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.