BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 36847820)

  • 1. High-throughput micronucleus assay using three-dimensional HepaRG spheroids for in vitro genotoxicity testing.
    Seo JE; Li X; Le Y; Mei N; Zhou T; Guo X
    Arch Toxicol; 2023 Apr; 97(4):1163-1175. PubMed ID: 36847820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing.
    Seo JE; Le Y; Revollo J; Miranda-Colon J; Xu H; McKinzie P; Mei N; Chen T; Heflich RH; Zhou T; Robison T; Bonzo JA; Guo X
    Arch Toxicol; 2024 Jun; 98(6):1919-1935. PubMed ID: 38584193
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of an in vitro three-dimensional HepaRG spheroid model for genotoxicity testing using the high-throughput CometChip platform.
    Seo JE; He X; Muskhelishvili L; Malhi P; Mei N; Manjanatha M; Bryant M; Zhou T; Robison T; Guo X
    ALTEX; 2022; 39(4):583-604. PubMed ID: 35791290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Performance of HepaRG and HepG2 cells in the high-throughput micronucleus assay for in vitro genotoxicity assessment.
    Guo X; Seo JE; Petibone D; Tryndyak V; Lee UJ; Zhou T; Robison TW; Mei N
    J Toxicol Environ Health A; 2020 Nov; 83(21-22):702-717. PubMed ID: 32981483
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models.
    Seo JE; Yu JZ; Xu H; Li X; Atrakchi AH; McGovern TJ; Bruno KLD; Mei N; Heflich RH; Guo X
    Arch Toxicol; 2023 Oct; 97(10):2785-2798. PubMed ID: 37486449
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay.
    Seo JE; Tryndyak V; Wu Q; Dreval K; Pogribny I; Bryant M; Zhou T; Robison TW; Mei N; Guo X
    Arch Toxicol; 2019 May; 93(5):1433-1448. PubMed ID: 30788552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay.
    Mandon M; Huet S; Dubreil E; Fessard V; Le Hégarat L
    Sci Rep; 2019 Jul; 9(1):10548. PubMed ID: 31332230
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies.
    Shah UK; Mallia JO; Singh N; Chapman KE; Doak SH; Jenkins GJS
    Mutat Res Genet Toxicol Environ Mutagen; 2018 Oct; 834():35-41. PubMed ID: 30173862
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Performance of comet and micronucleus assays in metabolic competent HepaRG cells to predict in vivo genotoxicity.
    Le Hégarat L; Mourot A; Huet S; Vasseur L; Camus S; Chesné C; Fessard V
    Toxicol Sci; 2014 Apr; 138(2):300-9. PubMed ID: 24431211
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
    Le Hegarat L; Dumont J; Josse R; Huet S; Lanceleur R; Mourot A; Poul JM; Guguen-Guillouzo C; Guillouzo A; Fessard V
    Mutagenesis; 2010 Nov; 25(6):555-60. PubMed ID: 20675360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Liver-on-chip model and application in predictive genotoxicity and mutagenicity of drugs.
    Kopp B; Khawam A; Di Perna K; Lenart D; Vinette M; Silva R; Zanoni TB; Rore C; Guenigault G; Richardson E; Kostrzewski T; Boswell A; Van P; Valentine Iii C; Salk J; Hamel A
    Mutat Res Genet Toxicol Environ Mutagen; 2024; 896():503762. PubMed ID: 38821675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Detection of urethane-induced genotoxicity in vitro using metabolically competent human 2D and 3D spheroid culture models.
    Shah UK; Verma JR; Chapman KE; Wilde EC; Tonkin JA; Brown MR; Johnson GE; Doak SH; Jenkins GJ
    Mutagenesis; 2020 Dec; 35(6):445-452. PubMed ID: 33219664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations.
    Conway GE; Shah UK; Llewellyn S; Cervena T; Evans SJ; Al Ali AS; Jenkins GJ; Clift MJD; Doak SH
    Mutagenesis; 2020 Sep; 35(4):319-330. PubMed ID: 32780103
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells.
    Quesnot N; Rondel K; Audebert M; Martinais S; Glaise D; Morel F; Loyer P; Robin MA
    Mutagenesis; 2016 Jan; 31(1):43-50. PubMed ID: 26282955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
    Rothfuss A; Honma M; Czich A; Aardema MJ; Burlinson B; Galloway S; Hamada S; Kirkland D; Heflich RH; Howe J; Nakajima M; O'Donovan M; Plappert-Helbig U; Priestley C; Recio L; Schuler M; Uno Y; Martus HJ
    Mutat Res; 2011 Aug; 723(2):108-20. PubMed ID: 21182982
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies.
    Shi J; Krsmanovic L; Bruce S; Kelly T; Paranjpe M; Szabo K; Arevalo M; Atta-Safoh S; Debelie F; LaForce MK; Sly J; Springer S
    Environ Mol Mutagen; 2011 Dec; 52(9):711-20. PubMed ID: 21976072
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of in vitro 3D cell model from hepatocellular carcinoma (HepG2) cell line and its application for genotoxicity testing.
    Štampar M; Tomc J; Filipič M; Žegura B
    Arch Toxicol; 2019 Nov; 93(11):3321-3333. PubMed ID: 31542801
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Application of HepaRG cells for genotoxicity assessment: a review.
    Guo X; Xu H; Seo JE
    J Environ Sci Health C Toxicol Carcinog; 2024 Apr; ():1-24. PubMed ID: 38566478
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies.
    Shah UK; Mallia JO; Singh N; Chapman KE; Doak SH; Jenkins GJS
    Mutat Res Genet Toxicol Environ Mutagen; 2018 Jan; 825():51-58. PubMed ID: 29307375
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An adaptation of the human HepaRG cells to the in vitro micronucleus assay.
    Jossé R; Rogue A; Lorge E; Guillouzo A
    Mutagenesis; 2012 May; 27(3):295-304. PubMed ID: 22058015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.