These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 36848492)

  • 1. On the identification of potential novel therapeutic targets for spinocerebellar ataxia type 1 (SCA1) neurodegenerative disease using EvoPPI3.
    Sousa A; Rocha S; Vieira J; Reboiro-Jato M; López-Fernández H; Vieira CP
    J Integr Bioinform; 2023 Jun; 20(2):. PubMed ID: 36848492
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms.
    Rocha S; Vieira J; Vázquez N; López-Fernández H; Fdez-Riverola F; Reboiro-Jato M; Sousa AD; Vieira CP
    BMC Med Genomics; 2019 Oct; 12(1):145. PubMed ID: 31655597
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase.
    Suart CE; Perez AM; Al-Ramahi I; Maiuri T; Botas J; Truant R
    Hum Mol Genet; 2021 May; 30(8):706-715. PubMed ID: 33772540
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1.
    Chen JM; Chen SK; Jin PP; Sun SC
    Hum Genomics; 2022 Jul; 16(1):29. PubMed ID: 35906672
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear bodies formed by polyQ-ataxin-1 protein are liquid RNA/protein droplets with tunable dynamics.
    Zhang S; Hinde E; Parkyn Schneider M; Jans DA; Bogoyevitch MA
    Sci Rep; 2020 Jan; 10(1):1557. PubMed ID: 32005838
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.
    Orr HT
    Prog Neurobiol; 2012 Dec; 99(3):179-85. PubMed ID: 22531670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
    Lee WS; Al-Ramahi I; Jeong HH; Jang Y; Lin T; Adamski CJ; Lavery LA; Rath S; Richman R; Bondar VV; Alcala E; Revelli JP; Orr HT; Liu Z; Botas J; Zoghbi HY
    J Clin Invest; 2022 May; 132(9):. PubMed ID: 35499073
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.
    Nitschke L; Coffin SL; Xhako E; El-Najjar DB; Orengo JP; Alcala E; Dai Y; Wan YW; Liu Z; Orr HT; Zoghbi HY
    JCI Insight; 2021 Feb; 6(3):. PubMed ID: 33554954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
    Kerkhof LMC; van de Warrenburg BPC; van Roon-Mom WMC; Buijsen RAM
    Biomolecules; 2023 May; 13(5):. PubMed ID: 37238658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
    Chen HK; Fernandez-Funez P; Acevedo SF; Lam YC; Kaytor MD; Fernandez MH; Aitken A; Skoulakis EM; Orr HT; Botas J; Zoghbi HY
    Cell; 2003 May; 113(4):457-68. PubMed ID: 12757707
    [TBL] [Abstract][Full Text] [Related]  

  • 11. EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases.
    Vázquez N; Rocha S; López-Fernández H; Torres A; Camacho R; Fdez-Riverola F; Vieira J; Vieira CP; Reboiro-Jato M
    Interdiscip Sci; 2019 Mar; 11(1):45-56. PubMed ID: 30707359
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN; Belozor OS; Mozhei OI; Shuvaev AN; Fritsler YV; Khilazheva ED; Mosyagina AI; Hirai H; Teschemacher AG; Kasparov S
    Cells; 2022 Jul; 11(14):. PubMed ID: 35883691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purkinje cell COX deficiency and mtDNA depletion in an animal model of spinocerebellar ataxia type 1.
    Ripolone M; Lucchini V; Ronchi D; Fagiolari G; Bordoni A; Fortunato F; Mondello S; Bonato S; Meregalli M; Torrente Y; Corti S; Comi GP; Moggio M; Sciacco M
    J Neurosci Res; 2018 Sep; 96(9):1576-1585. PubMed ID: 30113722
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish.
    Elsaey MA; Namikawa K; Köster RW
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298970
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
    Ding Y; Adachi H; Katsuno M; Sahashi K; Kondo N; Iida M; Tohnai G; Nakatsuji H; Sobue G
    Neuroscience; 2016 Jul; 327():20-31. PubMed ID: 27058144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
    Sánchez I; Piñol P; Corral-Juan M; Pandolfo M; Matilla-Dueñas A
    Hum Mol Genet; 2013 Sep; 22(17):3425-37. PubMed ID: 23630944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
    Park J; Al-Ramahi I; Tan Q; Mollema N; Diaz-Garcia JR; Gallego-Flores T; Lu HC; Lagalwar S; Duvick L; Kang H; Lee Y; Jafar-Nejad P; Sayegh LS; Richman R; Liu X; Gao Y; Shaw CA; Arthur JSC; Orr HT; Westbrook TF; Botas J; Zoghbi HY
    Nature; 2013 Jun; 498(7454):325-331. PubMed ID: 23719381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways.
    Zhang S; Williamson NA; Duvick L; Lee A; Orr HT; Korlin-Downs A; Yang P; Mok YF; Jans DA; Bogoyevitch MA
    Nat Commun; 2020 Jul; 11(1):3343. PubMed ID: 32620905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation.
    Krol HA; Krawczyk PM; Bosch KS; Aten JA; Hol EM; Reits EA
    PLoS One; 2008 Jan; 3(1):e1503. PubMed ID: 18231590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 14-3-3 proteins and spinocerebellar ataxia type 1: from molecular interaction to human neuropathology.
    Umahara T; Uchihara T
    Cerebellum; 2010 Jun; 9(2):183-9. PubMed ID: 20155408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.