These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 36848776)

  • 1. The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors.
    Zhang L; Mobbs JI; May LT; Glukhova A; Thal DM
    Curr Opin Struct Biol; 2023 Apr; 79():102560. PubMed ID: 36848776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
    Lu S; Zhang J
    J Med Chem; 2019 Jan; 62(1):24-45. PubMed ID: 29457894
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric modulation of GPCRs: From structural insights to in silico drug discovery.
    Persechino M; Hedderich JB; Kolb P; Hilger D
    Pharmacol Ther; 2022 Sep; 237():108242. PubMed ID: 35863587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT; Watson J; Bertekap R; Alt A
    Biochem Pharmacol; 2011 Mar; 81(6):691-702. PubMed ID: 21184747
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Does the Lipid Bilayer Orchestrate Access and Binding of Ligands to Transmembrane Orthosteric/Allosteric Sites of G Protein-Coupled Receptors?
    Szlenk CT; Gc JB; Natesan S
    Mol Pharmacol; 2019 Nov; 96(5):527-541. PubMed ID: 30967440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric binding sites at the receptor-lipid bilayer interface: novel targets for GPCR drug discovery.
    Wang Y; Yu Z; Xiao W; Lu S; Zhang J
    Drug Discov Today; 2021 Mar; 26(3):690-703. PubMed ID: 33301977
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism.
    Duan J; He XH; Li SJ; Xu HE
    Nat Rev Endocrinol; 2024 Jun; 20(6):349-365. PubMed ID: 38424377
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel Allosteric Modulators of G Protein-coupled Receptors.
    Gentry PR; Sexton PM; Christopoulos A
    J Biol Chem; 2015 Aug; 290(32):19478-88. PubMed ID: 26100627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric Modulators of the Class A G Protein Coupled Receptors.
    Tschammer N
    Adv Exp Med Biol; 2016; 917():185-207. PubMed ID: 27236557
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure determination of GPCRs: cryo-EM compared with X-ray crystallography.
    García-Nafría J; Tate CG
    Biochem Soc Trans; 2021 Nov; 49(5):2345-2355. PubMed ID: 34581758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Covalent allosteric modulation: An emerging strategy for GPCRs drug discovery.
    Bian Y; Jun JJ; Cuyler J; Xie XQ
    Eur J Med Chem; 2020 Nov; 206():112690. PubMed ID: 32818870
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Emerging opportunities for allosteric modulation of G-protein coupled receptors.
    Wang CI; Lewis RJ
    Biochem Pharmacol; 2013 Jan; 85(2):153-62. PubMed ID: 22975406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts.
    Wold EA; Chen J; Cunningham KA; Zhou J
    J Med Chem; 2019 Jan; 62(1):88-127. PubMed ID: 30106578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery.
    Zhang M; Lan X; Li X; Lu S
    Drug Discov Today; 2023 Dec; 28(12):103803. PubMed ID: 37852356
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural insights into G-protein-coupled receptor allostery.
    Thal DM; Glukhova A; Sexton PM; Christopoulos A
    Nature; 2018 Jul; 559(7712):45-53. PubMed ID: 29973731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors.
    Wootten D; Miller LJ
    Annu Rev Pharmacol Toxicol; 2020 Jan; 60():89-107. PubMed ID: 31454292
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GPCR Allosteric Modulator Discovery.
    Wu Y; Tong J; Ding K; Zhou Q; Zhao S
    Adv Exp Med Biol; 2019; 1163():225-251. PubMed ID: 31707706
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacology of Free Fatty Acid Receptors and Their Allosteric Modulators.
    Grundmann M; Bender E; Schamberger J; Eitner F
    Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33578942
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cryo-EM advances in GPCR structure determination.
    Shihoya W; Iwama A; Sano FK; Nureki O
    J Biochem; 2024 Jul; 176(1):1-10. PubMed ID: 38498911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
    Janero DR; Thakur GA
    Expert Opin Drug Discov; 2016 Dec; 11(12):1223-1237. PubMed ID: 27712124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.