BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 36849761)

  • 1. Inhibition mechanism of MRTX1133 on KRAS
    Liang F; Kang Z; Sun X; Chen J; Duan X; He H; Cheng J
    J Comput Aided Mol Des; 2023 Mar; 37(3):157-166. PubMed ID: 36849761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the binding of MRTX1133 as an avenue for the discovery of potential KRAS
    Issahaku AR; Mukelabai N; Agoni C; Rudrapal M; Aldosari SM; Almalki SG; Khan J
    Sci Rep; 2022 Oct; 12(1):17796. PubMed ID: 36273239
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cetuximab Enhances the Efficacy of MRTX1133, a Novel KRAS
    Kataoka M; Kitazawa M; Nakamura S; Koyama M; Yamamoto Y; Miyazaki S; Hondo N; Tanaka H; Soejima Y
    Anticancer Res; 2023 Oct; 43(10):4341-4348. PubMed ID: 37772552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Feedback activation of EGFR/wild-type RAS signaling axis limits KRAS
    Feng J; Hu Z; Xia X; Liu X; Lian Z; Wang H; Wang L; Wang C; Zhang X; Pang X
    Oncogene; 2023 May; 42(20):1620-1633. PubMed ID: 37020035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Nonconserved Histidine Residue on KRAS Drives Paralog Selectivity of the KRASG12D Inhibitor MRTX1133.
    Keats MA; Han JJW; Lee YH; Lee CS; Luo J
    Cancer Res; 2023 Sep; 83(17):2816-2823. PubMed ID: 37339170
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of MRTX1133, a Noncovalent, Potent, and Selective KRAS
    Wang X; Allen S; Blake JF; Bowcut V; Briere DM; Calinisan A; Dahlke JR; Fell JB; Fischer JP; Gunn RJ; Hallin J; Laguer J; Lawson JD; Medwid J; Newhouse B; Nguyen P; O'Leary JM; Olson P; Pajk S; Rahbaek L; Rodriguez M; Smith CR; Tang TP; Thomas NC; Vanderpool D; Vigers GP; Christensen JG; Marx MA
    J Med Chem; 2022 Feb; 65(4):3123-3133. PubMed ID: 34889605
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anti-tumor efficacy of a potent and selective non-covalent KRAS
    Hallin J; Bowcut V; Calinisan A; Briere DM; Hargis L; Engstrom LD; Laguer J; Medwid J; Vanderpool D; Lifset E; Trinh D; Hoffman N; Wang X; David Lawson J; Gunn RJ; Smith CR; Thomas NC; Martinson M; Bergstrom A; Sullivan F; Bouhana K; Winski S; He L; Fernandez-Banet J; Pavlicek A; Haling JR; Rahbaek L; Marx MA; Olson P; Christensen JG
    Nat Med; 2022 Oct; 28(10):2171-2182. PubMed ID: 36216931
    [TBL] [Abstract][Full Text] [Related]  

  • 8. KRAS
    Mahadevan KK; McAndrews KM; LeBleu VS; Yang S; Lyu H; Li B; Sockwell AM; Kirtley ML; Morse SJ; Moreno Diaz BA; Kim MP; Feng N; Lopez AM; Guerrero PA; Paradiso F; Sugimoto H; Arian KA; Ying H; Barekatain Y; Sthanam LK; Kelly PJ; Maitra A; Heffernan TP; Kalluri R
    Cancer Cell; 2023 Sep; 41(9):1606-1620.e8. PubMed ID: 37625401
    [TBL] [Abstract][Full Text] [Related]  

  • 9. KRAS inhibitors: going noncovalent.
    Drosten M; Barbacid M
    Mol Oncol; 2022 Dec; 16(22):3911-3915. PubMed ID: 36383067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer.
    Wei D; Wang L; Zuo X; Maitra A; Bresalier RS
    Clin Cancer Res; 2024 Feb; 30(4):655-662. PubMed ID: 37831007
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of New KRAS G12D Inhibitors through Computer-Aided Drug Discovery Methods.
    Kulkarni AM; Kumar V; Parate S; Lee G; Yoon S; Lee KW
    Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformational and Dynamical Effects of Tyr32 Phosphorylation in K-Ras: Molecular Dynamics Simulation and Markov State Models Analysis.
    Khaled M; Gorfe A; Sayyed-Ahmad A
    J Phys Chem B; 2019 Sep; 123(36):7667-7675. PubMed ID: 31419909
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glimmers of hope for targeting oncogenic KRAS-G12D.
    Tang D; Kang R
    Cancer Gene Ther; 2023 Mar; 30(3):391-393. PubMed ID: 36414681
    [TBL] [Abstract][Full Text] [Related]  

  • 14. KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?
    Bannoura SF; Khan HY; Azmi AS
    Front Oncol; 2022; 12():1013902. PubMed ID: 36531078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
    Zhou C; Fan Z; Gu Y; Ge Z; Tao Z; Cui R; Li Y; Zhou G; Huo R; Gao M; Wang D; He W; Zheng M; Zhang S; Xu T
    J Med Chem; 2024 Jan; 67(2):1147-1167. PubMed ID: 38197882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Next batter up! Targeting cancers with KRAS-G12D mutations.
    Zeissig MN; Ashwood LM; Kondrashova O; Sutherland KD
    Trends Cancer; 2023 Nov; 9(11):955-967. PubMed ID: 37591766
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-
    Xiao X; Feng J; Ma J; Xia X; Liu X; Zhang J; Ding C; Pang X; Zhang A
    J Med Chem; 2023 Nov; 66(22):15524-15549. PubMed ID: 37921024
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oncogenic Kras
    Mahadevan KK; McAndrews KM; LeBleu VS; Yang S; Lyu H; Li B; Sockwell AM; Kirtley ML; Morse SJ; Moreno Diaz BA; Kim MP; Feng N; Lopez AM; Guerrero PA; Sugimoto H; Arian KA; Ying H; Barekatain Y; Kelly PJ; Maitra A; Heffernan TP; Kalluri R
    bioRxiv; 2023 Feb; ():. PubMed ID: 36824971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolomic, Proteomic, and Single-Cell Proteomic Analysis of Cancer Cells Treated with the KRAS
    Orsburn BC
    J Proteome Res; 2023 Dec; 22(12):3703-3713. PubMed ID: 37983312
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel Imidazo[1,2-a]pyridine derivative modulates active KRAS
    Ali Y; Khan AA; Alanazi AM; Fatima S; Kozmon S
    Int J Biol Macromol; 2024 May; 270(Pt 2):132477. PubMed ID: 38772459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.