209 related articles for article (PubMed ID: 36854448)
1. Addressing Transcriptional Dysregulation in Cancer through CDK9 Inhibition.
Toure MA; Koehler AN
Biochemistry; 2023 Mar; 62(6):1114-1123. PubMed ID: 36854448
[TBL] [Abstract][Full Text] [Related]
2. Molecular Insights on Selective and Specific Inhibitors of Cyclin Dependent Kinase 9 Enzyme (CDK9) for the Purpose of Cancer Therapy.
Karati D; Mahadik KSR; Trivedi P; Kumar D
Anticancer Agents Med Chem; 2023; 23(4):383-403. PubMed ID: 35708082
[TBL] [Abstract][Full Text] [Related]
3. CDK9 keeps RNA polymerase II on track.
Egloff S
Cell Mol Life Sci; 2021 Jul; 78(14):5543-5567. PubMed ID: 34146121
[TBL] [Abstract][Full Text] [Related]
4. Recent Developments in the Biology and Medicinal Chemistry of CDK9 Inhibitors: An Update.
Wu T; Qin Z; Tian Y; Wang J; Xu C; Li Z; Bian J
J Med Chem; 2020 Nov; 63(22):13228-13257. PubMed ID: 32866383
[TBL] [Abstract][Full Text] [Related]
5. The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression.
Hou T; Ray S; Brasier AR
J Biol Chem; 2007 Dec; 282(51):37091-102. PubMed ID: 17956865
[TBL] [Abstract][Full Text] [Related]
6. Cyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH-associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivo.
Pei Y; Du H; Singer J; Stamour C; Granitto S; Shuman S; Fisher RP
Mol Cell Biol; 2006 Feb; 26(3):777-88. PubMed ID: 16428435
[TBL] [Abstract][Full Text] [Related]
7. Targeting cyclin-dependent kinase 9 sensitizes medulloblastoma cells to chemotherapy.
Song H; Bhakat R; Kling MJ; Coulter DW; Chaturvedi NK; Ray S; Joshi SS
Biochem Biophys Res Commun; 2019 Dec; 520(2):250-256. PubMed ID: 31594641
[TBL] [Abstract][Full Text] [Related]
8. The CDK9/cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: a possible role in embryonic genome activation.
Oqani RK; Kim HR; Diao YF; Park CS; Jin DI
BMC Dev Biol; 2011 Jun; 11():33. PubMed ID: 21639898
[TBL] [Abstract][Full Text] [Related]
9. Cyclin T1/CDK9 interacts with influenza A virus polymerase and facilitates its association with cellular RNA polymerase II.
Zhang J; Li G; Ye X
J Virol; 2010 Dec; 84(24):12619-27. PubMed ID: 20943989
[TBL] [Abstract][Full Text] [Related]
10. A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.
Sansó M; Lee KM; Viladevall L; Jacques PÉ; Pagé V; Nagy S; Racine A; St Amour CV; Zhang C; Shokat KM; Schwer B; Robert F; Fisher RP; Tanny JC
PLoS Genet; 2012; 8(8):e1002822. PubMed ID: 22876190
[TBL] [Abstract][Full Text] [Related]
11. Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor.
Albert TK; Rigault C; Eickhoff J; Baumgart K; Antrecht C; Klebl B; Mittler G; Meisterernst M
Br J Pharmacol; 2014 Jan; 171(1):55-68. PubMed ID: 24102143
[TBL] [Abstract][Full Text] [Related]
12. CDK9-dependent RNA polymerase II pausing controls transcription initiation.
Gressel S; Schwalb B; Decker TM; Qin W; Leonhardt H; Eick D; Cramer P
Elife; 2017 Oct; 6():. PubMed ID: 28994650
[TBL] [Abstract][Full Text] [Related]
13. G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb).
Qi T; Tang W; Wang L; Zhai L; Guo L; Zeng X
J Biol Chem; 2011 Apr; 286(17):15171-81. PubMed ID: 21378166
[TBL] [Abstract][Full Text] [Related]
14. T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Dow EC; Liu H; Rice AP
J Cell Physiol; 2010 Jul; 224(1):84-93. PubMed ID: 20201073
[TBL] [Abstract][Full Text] [Related]
15. Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation.
Zaborowska J; Baumli S; Laitem C; O'Reilly D; Thomas PH; O'Hare P; Murphy S
PLoS One; 2014; 9(9):e107654. PubMed ID: 25233083
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation.
Kim YK; Bourgeois CF; Isel C; Churcher MJ; Karn J
Mol Cell Biol; 2002 Jul; 22(13):4622-37. PubMed ID: 12052871
[TBL] [Abstract][Full Text] [Related]
17. TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast.
Viladevall L; St Amour CV; Rosebrock A; Schneider S; Zhang C; Allen JJ; Shokat KM; Schwer B; Leatherwood JK; Fisher RP
Mol Cell; 2009 Mar; 33(6):738-51. PubMed ID: 19328067
[TBL] [Abstract][Full Text] [Related]
18. Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.
Larochelle S; Amat R; Glover-Cutter K; Sansó M; Zhang C; Allen JJ; Shokat KM; Bentley DL; Fisher RP
Nat Struct Mol Biol; 2012 Nov; 19(11):1108-15. PubMed ID: 23064645
[TBL] [Abstract][Full Text] [Related]
19. The emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE.
Paparidis NF; Durvale MC; Canduri F
Mol Biosyst; 2017 Jan; 13(2):246-276. PubMed ID: 27833949
[TBL] [Abstract][Full Text] [Related]
20. JMJD5 couples with CDK9 to release the paused RNA polymerase II.
Liu H; Ramachandran S; Fong N; Phang T; Lee S; Parsa P; Liu X; Harmacek L; Danhorn T; Song T; Oh S; Zhang Q; Chen Z; Zhang Q; Tu TH; Happoldt C; O'Conner B; Janknecht R; Li CY; Marrack P; Kappler J; Leach S; Zhang G
Proc Natl Acad Sci U S A; 2020 Aug; 117(33):19888-19895. PubMed ID: 32747552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]