These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 36858339)

  • 1. Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers.
    Yang Q; Qin T; An T; Wu H; Xu G; Xiang J; Lei K; Zhang S; Xia J; Su G; Wang D; Xue M; Kong L; Zhang W; Wu S; Li Y
    Eur J Pharmacol; 2023 Apr; 945():175628. PubMed ID: 36858339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.
    Proffitt KD; Madan B; Ke Z; Pendharkar V; Ding L; Lee MA; Hannoush RN; Virshup DM
    Cancer Res; 2013 Jan; 73(2):502-7. PubMed ID: 23188502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
    Liu J; Pan S; Hsieh MH; Ng N; Sun F; Wang T; Kasibhatla S; Schuller AG; Li AG; Cheng D; Li J; Tompkins C; Pferdekamper A; Steffy A; Cheng J; Kowal C; Phung V; Guo G; Wang Y; Graham MP; Flynn S; Brenner JC; Li C; Villarroel MC; Schultz PG; Wu X; McNamara P; Sellers WR; Petruzzelli L; Boral AL; Seidel HM; McLaughlin ME; Che J; Carey TE; Vanasse G; Harris JL
    Proc Natl Acad Sci U S A; 2013 Dec; 110(50):20224-9. PubMed ID: 24277854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease.
    Macyczko JR; Wang N; Zhao J; Ren Y; Lu W; Ikezu TC; Zhao N; Liu CC; Bu G; Li Y
    Mol Neurobiol; 2023 Jan; 60(1):26-35. PubMed ID: 36215026
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers.
    Zhong Z; Sepramaniam S; Chew XH; Wood K; Lee MA; Madan B; Virshup DM
    Oncogene; 2019 Oct; 38(40):6662-6677. PubMed ID: 31391551
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling.
    Galli LM; Zebarjadi N; Li L; Lingappa VR; Burrus LW
    Exp Cell Res; 2016 Sep; 347(1):171-183. PubMed ID: 27492485
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An
    Asciolla JJ; Miele MM; Hendrickson RC; Resh MD
    J Biol Chem; 2017 Aug; 292(33):13507-13513. PubMed ID: 28655768
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine
    Rao DM; Shackleford MT; Bordeaux EK; Sottnik JL; Ferguson RL; Yamamoto TM; Wellberg EA; Bitler BG; Sikora MJ
    J Biol Chem; 2019 Dec; 294(52):19950-19966. PubMed ID: 31740580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
    Li J; Wu G; Xu Y; Li J; Ruan N; Chen Y; Zhang Q; Xia Q
    Biomed Res Int; 2020; 2020():2527643. PubMed ID: 32104684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN).
    Tuladhar R; Yarravarapu N; Ma Y; Zhang C; Herbert J; Kim J; Chen C; Lum L
    J Biol Chem; 2019 Apr; 294(16):6273-6282. PubMed ID: 30737280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of key residues and regions important for porcupine-mediated Wnt acylation.
    Rios-Esteves J; Haugen B; Resh MD
    J Biol Chem; 2014 Jun; 289(24):17009-19. PubMed ID: 24798332
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Lee CJ; Rana MS; Bae C; Li Y; Banerjee A
    J Biol Chem; 2019 Jan; 294(1):231-245. PubMed ID: 30420431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of PORCN Blocks Wnt Signaling to Attenuate Progression of Oral Carcinogenesis.
    Peña-Oyarzún D; Flores T; Torres VA; Quest AFG; Lobos-González L; Kretschmar C; Contreras P; Maturana-Ramírez A; Criollo A; Reyes M
    Clin Cancer Res; 2024 Jan; 30(1):209-223. PubMed ID: 37812478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.
    Covey TM; Kaur S; Tan Ong T; Proffitt KD; Wu Y; Tan P; Virshup DM
    PLoS One; 2012; 7(4):e34532. PubMed ID: 22509316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Responses of Porcupine and Wntless proteins to oxidative, hypoxic and endoplasmic reticulum stresses.
    Mohamed R; Kennedy C; Willmore WG
    Cell Signal; 2021 Sep; 85():110047. PubMed ID: 34015469
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of Porcupine impairs convergent extension during gastrulation in zebrafish.
    Chen Q; Takada R; Takada S
    J Cell Sci; 2012 May; 125(Pt 9):2224-34. PubMed ID: 22357957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Porcn as a novel therapeutic target in cancer therapy:  A review.
    Raeisi M; Saberivand M; Velaei K; Aghaei N; Rahimi-Farsi N; Kharrati-Shishavan H; Hassanzadeh D; Mehdizadeh A
    Cell Biol Int; 2022 Dec; 46(12):1979-1991. PubMed ID: 35971741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulating Wnt signaling at the root: Porcupine and Wnt acylation.
    Torres VI; Godoy JA; Inestrosa NC
    Pharmacol Ther; 2019 Jun; 198():34-45. PubMed ID: 30790642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome.
    Barrott JJ; Cash GM; Smith AP; Barrow JR; Murtaugh LC
    Proc Natl Acad Sci U S A; 2011 Aug; 108(31):12752-7. PubMed ID: 21768372
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and Optimization of a Porcupine Inhibitor.
    Duraiswamy AJ; Lee MA; Madan B; Ang SH; Tan ES; Cheong WW; Ke Z; Pendharkar V; Ding LJ; Chew YS; Manoharan V; Sangthongpitag K; Alam J; Poulsen A; Ho SY; Virshup DM; Keller TH
    J Med Chem; 2015 Aug; 58(15):5889-99. PubMed ID: 26110200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.