These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 36859689)

  • 1. Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons.
    Christensen KR; Combs B; Richards C; Grabinski T; Alhadidy MM; Kanaan NM
    Mol Neurobiol; 2023 Jun; 60(6):3423-3438. PubMed ID: 36859689
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.
    Combs B; Christensen KR; Richards C; Kneynsberg A; Mueller RL; Morris SL; Morfini GA; Brady ST; Kanaan NM
    J Neurosci; 2021 Nov; 41(45):9431-9451. PubMed ID: 34607969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases.
    Kanaan NM; Morfini GA; LaPointe NE; Pigino GF; Patterson KR; Song Y; Andreadis A; Fu Y; Brady ST; Binder LI
    J Neurosci; 2011 Jul; 31(27):9858-68. PubMed ID: 21734277
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tau and Axonal Transport Misregulation in Tauopathies.
    Combs B; Mueller RL; Morfini G; Brady ST; Kanaan NM
    Adv Exp Med Biol; 2019; 1184():81-95. PubMed ID: 32096030
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition.
    Cox K; Combs B; Abdelmesih B; Morfini G; Brady ST; Kanaan NM
    Neurobiol Aging; 2016 Nov; 47():113-126. PubMed ID: 27574109
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport.
    Tiernan CT; Combs B; Cox K; Morfini G; Brady ST; Counts SE; Kanaan NM
    Exp Neurol; 2016 Sep; 283(Pt A):318-29. PubMed ID: 27373205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pattern of human tau phosphorylation is the result of priming and feedback events in primary hippocampal neurons.
    Bertrand J; Plouffe V; Sénéchal P; Leclerc N
    Neuroscience; 2010 Jun; 168(2):323-34. PubMed ID: 20394726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tau phosphorylation and PAD exposure in regulation of axonal growth.
    Morris SL; Brady ST
    Front Cell Dev Biol; 2022; 10():1023418. PubMed ID: 36742197
    [No Abstract]   [Full Text] [Related]  

  • 9. Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons.
    Lacovich V; Espindola SL; Alloatti M; Pozo Devoto V; Cromberg LE; Čarná ME; Forte G; Gallo JM; Bruno L; Stokin GB; Avale ME; Falzone TL
    J Neurosci; 2017 Jan; 37(1):58-69. PubMed ID: 28053030
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.
    Combs B; Hamel C; Kanaan NM
    Neurobiol Dis; 2016 Oct; 94():18-31. PubMed ID: 27260838
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau.
    Bertrand J; Sénéchal P; Zummo-Soucy M; Plouffe V; Leclerc N
    J Neurochem; 2010 Sep; 114(5):1353-67. PubMed ID: 20550628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons.
    Ramser EM; Gan KJ; Decker H; Fan EY; Suzuki MM; Ferreira ST; Silverman MA
    Mol Biol Cell; 2013 Aug; 24(16):2494-505. PubMed ID: 23783030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
    Zhang B; Yao Y; Cornec AS; Oukoloff K; James MJ; Koivula P; Trojanowski JQ; Smith AB; Lee VM; Ballatore C; Brunden KR
    Mol Neurodegener; 2018 Nov; 13(1):59. PubMed ID: 30404654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defined Tau Phosphospecies Differentially Inhibit Fast Axonal Transport Through Activation of Two Independent Signaling Pathways.
    Morris SL; Tsai MY; Aloe S; Bechberger K; König S; Morfini G; Brady ST
    Front Mol Neurosci; 2020; 13():610037. PubMed ID: 33568975
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.
    Kanaan NM; Morfini G; Pigino G; LaPointe NE; Andreadis A; Song Y; Leitman E; Binder LI; Brady ST
    Neurobiol Aging; 2012 Apr; 33(4):826.e15-30. PubMed ID: 21794954
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease.
    Chiasseu M; Alarcon-Martinez L; Belforte N; Quintero H; Dotigny F; Destroismaisons L; Vande Velde C; Panayi F; Louis C; Di Polo A
    Mol Neurodegener; 2017 Aug; 12(1):58. PubMed ID: 28774322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies.
    Hart de Ruyter FJ; Morrema THJ; den Haan J; ; Twisk JWR; de Boer JF; Scheltens P; Boon BDC; Thal DR; Rozemuller AJ; Verbraak FD; Bouwman FH; Hoozemans JJM
    Acta Neuropathol; 2023 Feb; 145(2):197-218. PubMed ID: 36480077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease.
    Shahpasand K; Uemura I; Saito T; Asano T; Hata K; Shibata K; Toyoshima Y; Hasegawa M; Hisanaga S
    J Neurosci; 2012 Feb; 32(7):2430-41. PubMed ID: 22396417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways.
    Christensen KR; Beach TG; Serrano GE; Kanaan NM
    Acta Neuropathol Commun; 2019 Feb; 7(1):29. PubMed ID: 30819250
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice.
    Onishi T; Matsumoto Y; Hattori M; Obayashi Y; Nakamura K; Yano T; Horiguchi T; Iwashita H
    Neurosci Res; 2014 Mar; 80():76-85. PubMed ID: 24406748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.