BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

321 related articles for article (PubMed ID: 36883553)

  • 1. Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns.
    Sørensen SG; Shrikhande A; Poulsgaard GA; Christensen MH; Bertl J; Laursen BE; Hoffmann ER; Pedersen JS
    Elife; 2023 Mar; 12():. PubMed ID: 36883553
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrative genomic analysis identifies associations of molecular alterations to APOBEC and BRCA1/2 mutational signatures in breast cancer.
    Trevino V
    Mol Genet Genomic Med; 2019 Aug; 7(8):e810. PubMed ID: 31294536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies.
    Stok C; Kok YP; van den Tempel N; van Vugt MATM
    Nucleic Acids Res; 2021 May; 49(8):4239-4257. PubMed ID: 33744950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations.
    Sztupinszki Z; Diossy M; Krzystanek M; Borcsok J; Pomerantz MM; Tisza V; Spisak S; Rusz O; Csabai I; Freedman ML; Szallasi Z
    Clin Cancer Res; 2020 Jun; 26(11):2673-2680. PubMed ID: 32071115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A mutational signature in gastric cancer suggests therapeutic strategies.
    Alexandrov LB; Nik-Zainal S; Siu HC; Leung SY; Stratton MR
    Nat Commun; 2015 Oct; 6():8683. PubMed ID: 26511885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Homologous Recombination Defects and Mutations in DNA Damage Response (DDR) Genes Besides
    Voutsadakis IA; Stravodimou A
    Anticancer Res; 2023 Mar; 43(3):967-981. PubMed ID: 36854505
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of Somatically Acquired
    Vidula N; Dubash T; Lawrence MS; Simoneau A; Niemierko A; Blouch E; Nagy B; Roh W; Chirn B; Reeves BA; Malvarosa G; Lennerz J; Isakoff SJ; Juric D; Micalizzi D; Wander S; Spring L; Moy B; Shannon K; Younger J; Lanman R; Toner M; Iafrate AJ; Getz G; Zou L; Ellisen LW; Maheswaran S; Haber DA; Bardia A
    Clin Cancer Res; 2020 Sep; 26(18):4852-4862. PubMed ID: 32571788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A meta-analysis of reversion mutations in BRCA genes identifies signatures of DNA end-joining repair mechanisms driving therapy resistance.
    Tobalina L; Armenia J; Irving E; O'Connor MJ; Forment JV
    Ann Oncol; 2021 Jan; 32(1):103-112. PubMed ID: 33091561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
    White JA; Kaninjing ET; Adeniji KA; Jibrin P; Obafunwa JO; Ogo CN; Mohammed F; Popoola A; Fatiregun OA; Oluwole OP; Karanam B; Elhussin I; Ambs S; Tang W; Davis M; Polak P; Campbell MJ; Brignole KR; Rotimi SO; Dean-Colomb W; Odedina FT; Martin DN; Yates C
    Cancer Res Commun; 2022 Sep; 2(9):1005-1016. PubMed ID: 36922933
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA Repair Deficiency Is Common in Advanced Prostate Cancer: New Therapeutic Opportunities.
    Dhawan M; Ryan CJ; Ashworth A
    Oncologist; 2016 Aug; 21(8):940-5. PubMed ID: 27317574
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trajectory and uniqueness of mutational signatures in yeast mutators.
    Loeillet S; Herzog M; Puddu F; Legoix P; Baulande S; Jackson SP; Nicolas AG
    Proc Natl Acad Sci U S A; 2020 Oct; 117(40):24947-24956. PubMed ID: 32968016
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Homologous recombination deficiency: how genomic signatures are generated.
    Setton J; Reis-Filho JS; Powell SN
    Curr Opin Genet Dev; 2021 Feb; 66():93-100. PubMed ID: 33477018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of mutational signatures in C. elegans: Implications for cancer genome analysis.
    Meier B; Volkova NV; Gerstung M; Gartner A
    DNA Repair (Amst); 2020 Nov; 95():102957. PubMed ID: 32980770
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Therapeutic exploitation of tumor cell defects in homologous recombination.
    Powell SN; Kachnic LA
    Anticancer Agents Med Chem; 2008 May; 8(4):448-60. PubMed ID: 18473729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
    Lhota F; Zemankova P; Kleiblova P; Soukupova J; Vocka M; Stranecky V; Janatova M; Hartmannova H; Hodanova K; Kmoch S; Kleibl Z
    Clin Genet; 2016 Oct; 90(4):324-33. PubMed ID: 26822949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
    Wang H; Zeng ZC; Bui TA; DiBiase SJ; Qin W; Xia F; Powell SN; Iliakis G
    Cancer Res; 2001 Jan; 61(1):270-7. PubMed ID: 11196174
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Testing of mutations in BRCA1 and BRCA2 genes in tumor tissues - possibilities and limitations].
    Vošmiková H; Ryška A; Sieglová K; Laco J
    Cesk Patol; 2016; 52(4):210-214. PubMed ID: 27869447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers.
    Watkins JA; Irshad S; Grigoriadis A; Tutt AN
    Breast Cancer Res; 2014 Jun; 16(3):211. PubMed ID: 25093514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency.
    Meier B; Cooke SL; Weiss J; Bailly AP; Alexandrov LB; Marshall J; Raine K; Maddison M; Anderson E; Stratton MR; Gartner A; Campbell PJ
    Genome Res; 2014 Oct; 24(10):1624-36. PubMed ID: 25030888
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.
    Tram E; Savas S; Ozcelik H
    PLoS One; 2013; 8(5):e62468. PubMed ID: 23704879
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.