BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 36893265)

  • 1. Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
    Tsutsumi N; Hwang S; Waghray D; Hansen S; Jude KM; Wang N; Miao Y; Glassman CR; Caveney NA; Janda CY; Hannoush RN; Garcia KC
    Proc Natl Acad Sci U S A; 2023 Mar; 120(11):e2218238120. PubMed ID: 36893265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
    Ring L; Neth P; Weber C; Steffens S; Faussner A
    Cell Signal; 2014 Feb; 26(2):260-7. PubMed ID: 24269653
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.
    Zeng X; Huang H; Tamai K; Zhang X; Harada Y; Yokota C; Almeida K; Wang J; Doble B; Woodgett J; Wynshaw-Boris A; Hsieh JC; He X
    Development; 2008 Jan; 135(2):367-75. PubMed ID: 18077588
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface.
    Li M; Zheng J; Luo D; Xu K; Sheng R; MacDonald BT; He X; Zhang X
    EMBO Rep; 2023 Jun; 24(6):e55873. PubMed ID: 36994853
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.
    Bourhis E; Tam C; Franke Y; Bazan JF; Ernst J; Hwang J; Costa M; Cochran AG; Hannoush RN
    J Biol Chem; 2010 Mar; 285(12):9172-9. PubMed ID: 20093360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.
    Grumolato L; Liu G; Mong P; Mudbhary R; Biswas R; Arroyave R; Vijayakumar S; Economides AN; Aaronson SA
    Genes Dev; 2010 Nov; 24(22):2517-30. PubMed ID: 21078818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.
    Chen J; Yan H; Ren DN; Yin Y; Li Z; He Q; Wo D; Ho MS; Chen Y; Liu Z; Yang J; Liu S; Zhu W
    Cell Signal; 2014 May; 26(5):1068-74. PubMed ID: 24412751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
    Janda CY; Dang LT; You C; Chang J; de Lau W; Zhong ZA; Yan KS; Marecic O; Siepe D; Li X; Moody JD; Williams BO; Clevers H; Piehler J; Baker D; Kuo CJ; Garcia KC
    Nature; 2017 May; 545(7653):234-237. PubMed ID: 28467818
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.
    Nam JS; Turcotte TJ; Smith PF; Choi S; Yoon JK
    J Biol Chem; 2006 May; 281(19):13247-13257. PubMed ID: 16543246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering.
    Thakur AK; Miller SE; Liau NPD; Hwang S; Hansen S; de Sousa E Melo F; Sudhamsu J; Hannoush RN
    ACS Chem Biol; 2023 Apr; 18(4):772-784. PubMed ID: 36893429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization.
    DeBruine ZJ; Ke J; Harikumar KG; Gu X; Borowsky P; Williams BO; Xu W; Miller LJ; Xu HE; Melcher K
    Genes Dev; 2017 May; 31(9):916-926. PubMed ID: 28546512
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Immunocytochemical Analysis of Endogenous Frizzled-(Co-)Receptor Interactions and Rapid Wnt Pathway Activation in Mammalian Cells.
    Neuhaus J; Weimann A; Berndt-Paetz M
    Int J Mol Sci; 2021 Nov; 22(21):. PubMed ID: 34769487
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes.
    Kim I; Pan W; Jones SA; Zhang Y; Zhuang X; Wu D
    J Cell Biol; 2013 Feb; 200(4):419-28. PubMed ID: 23400998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway.
    Hua Y; Yang Y; Li Q; He X; Zhu W; Wang J; Gan X
    J Biol Chem; 2018 Dec; 293(51):19710-19724. PubMed ID: 30361437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.
    Ahn VE; Chu ML; Choi HJ; Tran D; Abo A; Weis WI
    Dev Cell; 2011 Nov; 21(5):862-73. PubMed ID: 22000856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies.
    Gong Y; Bourhis E; Chiu C; Stawicki S; DeAlmeida VI; Liu BY; Phamluong K; Cao TC; Carano RA; Ernst JA; Solloway M; Rubinfeld B; Hannoush RN; Wu Y; Polakis P; Costa M
    PLoS One; 2010 Sep; 5(9):e12682. PubMed ID: 20856934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.
    Tsutsumi N; Mukherjee S; Waghray D; Janda CY; Jude KM; Miao Y; Burg JS; Aduri NG; Kossiakoff AA; Gati C; Garcia KC
    Elife; 2020 Aug; 9():. PubMed ID: 32762848
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.
    Semënov MV; Tamai K; Brott BK; Kühl M; Sokol S; He X
    Curr Biol; 2001 Jun; 11(12):951-61. PubMed ID: 11448771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling.
    MacDonald BT; He X
    Cold Spring Harb Perspect Biol; 2012 Dec; 4(12):. PubMed ID: 23209147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LRPs in WNT Signalling.
    Davidson G
    Handb Exp Pharmacol; 2021; 269():45-73. PubMed ID: 34490514
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.