177 related articles for article (PubMed ID: 36894641)
1. Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR
Thompson D; Mahmood S; Morrice N; Kamli-Salino S; Dekeryte R; Hoffmann PA; Doherty MK; Whitfield PD; Delibegović M; Mody N
Sci Rep; 2023 Mar; 13(1):3937. PubMed ID: 36894641
[TBL] [Abstract][Full Text] [Related]
2. Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis.
Kasumov T; Li L; Li M; Gulshan K; Kirwan JP; Liu X; Previs S; Willard B; Smith JD; McCullough A
PLoS One; 2015; 10(5):e0126910. PubMed ID: 25993337
[TBL] [Abstract][Full Text] [Related]
3. Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue.
Mcilroy GD; Tammireddy SR; Maskrey BH; Grant L; Doherty MK; Watson DG; Delibegović M; Whitfield PD; Mody N
Biochem Pharmacol; 2016 Jan; 100():86-97. PubMed ID: 26592777
[TBL] [Abstract][Full Text] [Related]
4. Fenretinide ameliorates insulin resistance and fatty liver in obese mice.
Koh IU; Jun HS; Choi JS; Lim JH; Kim WH; Yoon JB; Song J
Biol Pharm Bull; 2012; 35(3):369-75. PubMed ID: 22382323
[TBL] [Abstract][Full Text] [Related]
5. Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism.
Lu Z; Li Y; Syn WK; Wang Z; Lopes-Virella MF; Lyons TJ; Huang Y
Am J Physiol Endocrinol Metab; 2020 Feb; 318(2):E131-E144. PubMed ID: 31821039
[TBL] [Abstract][Full Text] [Related]
6. Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice.
Morrice N; Mcilroy GD; Tammireddy SR; Reekie J; Shearer KD; Doherty MK; Delibegović M; Whitfield PD; Mody N
Sci Rep; 2017 Mar; 7():43782. PubMed ID: 28256636
[TBL] [Abstract][Full Text] [Related]
7. Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis.
Bikman BT; Guan Y; Shui G; Siddique MM; Holland WL; Kim JY; Fabriàs G; Wenk MR; Summers SA
J Biol Chem; 2012 May; 287(21):17426-17437. PubMed ID: 22474281
[TBL] [Abstract][Full Text] [Related]
8. The ketogenic diet prevents steatosis and insulin resistance by reducing lipogenesis, diacylglycerol accumulation and protein kinase C activity in male rat liver.
Jani S; Da Eira D; Stefanovic M; Ceddia RB
J Physiol; 2022 Sep; 600(18):4137-4151. PubMed ID: 35974660
[TBL] [Abstract][Full Text] [Related]
9. A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology.
van den Hoek AM; Verschuren L; Worms N; van Nieuwkoop A; de Ruiter C; Attema J; Menke AL; Caspers MPM; Radhakrishnan S; Salic K; Kleemann R
Cells; 2020 Sep; 9(9):. PubMed ID: 32883049
[TBL] [Abstract][Full Text] [Related]
10. Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus.
Mcilroy GD; Delibegovic M; Owen C; Stoney PN; Shearer KD; McCaffery PJ; Mody N
Diabetes; 2013 Mar; 62(3):825-36. PubMed ID: 23193184
[TBL] [Abstract][Full Text] [Related]
11. Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice.
Srivastava RA; Jahagirdar R; Azhar S; Sharma S; Bisgaier CL
Mol Cell Biochem; 2006 Apr; 285(1-2):35-50. PubMed ID: 16477380
[TBL] [Abstract][Full Text] [Related]
12. Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis.
Wu Q; Sun L; Hu X; Wang X; Xu F; Chen B; Liang X; Xia J; Wang P; Aibara D; Zhang S; Zeng G; Yun C; Yan Y; Zhu Y; Bustin M; Zhang S; Gonzalez FJ; Jiang C
J Clin Invest; 2021 May; 131(9):. PubMed ID: 33938457
[TBL] [Abstract][Full Text] [Related]
13. Grape pomace reduces the severity of non-alcoholic hepatic steatosis and the development of steatohepatitis by improving insulin sensitivity and reducing ectopic fat deposition in mice.
Daniel T; Ben-Shachar M; Drori E; Hamad S; Permyakova A; Ben-Cnaan E; Tam J; Kerem Z; Rosenzweig T
J Nutr Biochem; 2021 Dec; 98():108867. PubMed ID: 34571189
[TBL] [Abstract][Full Text] [Related]
14. Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide.
Lovat PE; Di Sano F; Corazzari M; Fazi B; Donnorso RP; Pearson AD; Hall AG; Redfern CP; Piacentini M
J Natl Cancer Inst; 2004 Sep; 96(17):1288-99. PubMed ID: 15339967
[TBL] [Abstract][Full Text] [Related]
15. Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet.
Deevska GM; Sunkara M; Morris AJ; Nikolova-Karakashian MN
Biosci Rep; 2012 Oct; 32(5):479-90. PubMed ID: 22712892
[TBL] [Abstract][Full Text] [Related]
16. The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes.
Mody N; Mcilroy GD
Biochem Pharmacol; 2014 Oct; 91(3):277-86. PubMed ID: 25069047
[TBL] [Abstract][Full Text] [Related]
17. A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice.
Schoemaker MH; Kleemann R; Morrison MC; Verheij J; Salic K; van Tol EAF; Kooistra T; Wielinga PY
PLoS One; 2017; 12(7):e0180648. PubMed ID: 28678821
[TBL] [Abstract][Full Text] [Related]
18. Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice.
Coenen KR; Hasty AH
Am J Physiol Endocrinol Metab; 2007 Aug; 293(2):E492-9. PubMed ID: 17566116
[TBL] [Abstract][Full Text] [Related]
19. FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice.
Rohrbach TD; Asgharpour A; Maczis MA; Montefusco D; Cowart LA; Bedossa P; Sanyal AJ; Spiegel S
J Lipid Res; 2019 Jul; 60(7):1311-1322. PubMed ID: 31110049
[TBL] [Abstract][Full Text] [Related]
20. The Presence of Periodontitis Exacerbates Non-Alcoholic Fatty Liver Disease via Sphingolipid Metabolism-Associated Insulin Resistance and Hepatic Inflammation in Mice with Metabolic Syndrome.
Lu Z; Li Y; Chowdhury N; Yu H; Syn WK; Lopes-Virella M; Yilmaz Ö; Huang Y
Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37176029
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
