BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 36899949)

  • 1. Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK.
    Borkowsky S; Gass M; Alavizargar A; Hanewinkel J; Hallstein I; Nedvetsky P; Heuer A; Krahn MP
    Cells; 2023 Mar; 12(5):. PubMed ID: 36899949
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.
    Xie Z; Dong Y; Zhang M; Cui MZ; Cohen RA; Riek U; Neumann D; Schlattner U; Zou MH
    J Biol Chem; 2006 Mar; 281(10):6366-75. PubMed ID: 16407220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.
    Shaw RJ; Kosmatka M; Bardeesy N; Hurley RL; Witters LA; DePinho RA; Cantley LC
    Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3329-35. PubMed ID: 14985505
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
    Nagalingam A; Arbiser JL; Bonner MY; Saxena NK; Sharma D
    Breast Cancer Res; 2012 Feb; 14(1):R35. PubMed ID: 22353783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AMPK Causes Cell Cycle Arrest in LKB1-Deficient Cells via Activation of CAMKK2.
    Fogarty S; Ross FA; Vara Ciruelos D; Gray A; Gowans GJ; Hardie DG
    Mol Cancer Res; 2016 Aug; 14(8):683-95. PubMed ID: 27141100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of serine 399 in LKB1 protein short form by protein kinase Cζ is required for its nucleocytoplasmic transport and consequent AMP-activated protein kinase (AMPK) activation.
    Zhu H; Moriasi CM; Zhang M; Zhao Y; Zou MH
    J Biol Chem; 2013 Jun; 288(23):16495-16505. PubMed ID: 23612973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.
    Jaleel M; Villa F; Deak M; Toth R; Prescott AR; Van Aalten DM; Alessi DR
    Biochem J; 2006 Mar; 394(Pt 3):545-55. PubMed ID: 16396636
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LKB1 and AMPK maintain epithelial cell polarity under energetic stress.
    Mirouse V; Swick LL; Kazgan N; St Johnston D; Brenman JE
    J Cell Biol; 2007 May; 177(3):387-92. PubMed ID: 17470638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A comparison of LKB1/AMPK/mTOR metabolic axis response to global ischaemia in brain, heart, liver and kidney in a rat model of cardiac arrest.
    Majd S; Power JHT; Chataway TK; Grantham HJM
    BMC Cell Biol; 2018 Jun; 19(1):7. PubMed ID: 29921218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties.
    MacDonald AF; Bettaieb A; Donohoe DR; Alani DS; Han A; Zhao Y; Whelan J
    BMC Complement Altern Med; 2018 Jun; 18(1):188. PubMed ID: 29914450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1.
    Mung KL; Eccleshall WB; Santio NM; Rivero-Müller A; Koskinen PJ
    Cell Commun Signal; 2021 Jun; 19(1):68. PubMed ID: 34193159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
    Xie Z; Dong Y; Scholz R; Neumann D; Zou MH
    Circulation; 2008 Feb; 117(7):952-62. PubMed ID: 18250273
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.
    Akasaka Y; Hasei S; Ohata Y; Kanna M; Nakatsu Y; Sakoda H; Fujishiro M; Kushiyama A; Ono H; Matsubara A; Hinata N; Asano T; Yamamotoya T
    Int J Mol Sci; 2023 Nov; 24(21):. PubMed ID: 37958994
    [No Abstract]   [Full Text] [Related]  

  • 14. Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.
    Houde VP; Ritorto MS; Gourlay R; Varghese J; Davies P; Shpiro N; Sakamoto K; Alessi DR
    Biochem J; 2014 Feb; 458(1):41-56. PubMed ID: 24295069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression.
    Dogliotti G; Kullmann L; Dhumale P; Thiele C; Panichkina O; Mendl G; Houben R; Haferkamp S; Püschel AW; Krahn MP
    Nat Commun; 2017 Jun; 8():15747. PubMed ID: 28649994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.
    Vázquez-Chantada M; Ariz U; Varela-Rey M; Embade N; Martínez-Lopez N; Fernández-Ramos D; Gómez-Santos L; Lamas S; Lu SC; Martínez-Chantar ML; Mato JM
    Hepatology; 2009 Feb; 49(2):608-17. PubMed ID: 19177591
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of the LKB1-AMPK pathway by the Epstein-Barr virus-encoded LMP1 promotes proliferation and transformation of human nasopharyngeal epithelial cells.
    Lo AK; Lo KW; Ko CW; Young LS; Dawson CW
    J Pathol; 2013 Jul; 230(3):336-46. PubMed ID: 23592276
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification.
    Behunin SM; Lopez-Pier MA; Birch CL; McKee LAK; Danilo C; Khalpey Z; Konhilas JP
    Biophys J; 2015 Mar; 108(6):1484-1494. PubMed ID: 25809261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.
    Fogarty S; Hardie DG
    J Biol Chem; 2009 Jan; 284(1):77-84. PubMed ID: 18854318
    [TBL] [Abstract][Full Text] [Related]  

  • 20. eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1.
    Thors B; Halldórsson H; Thorgeirsson G
    Biochim Biophys Acta; 2011 Feb; 1813(2):322-31. PubMed ID: 21145922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.