BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 36904854)

  • 21. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol.
    Polanco JC; Hand GR; Briner A; Li C; Götz J
    Acta Neuropathol; 2021 Feb; 141(2):235-256. PubMed ID: 33417012
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A Novel NIR-FRET Biosensor for Reporting PS/γ-Secretase Activity in Live Cells.
    Houser MC; Hou SS; Perrin F; Turchyna Y; Bacskai BJ; Berezovska O; Maesako M
    Sensors (Basel); 2020 Oct; 20(21):. PubMed ID: 33105735
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The substrate repertoire of γ-secretase/presenilin.
    Güner G; Lichtenthaler SF
    Semin Cell Dev Biol; 2020 Sep; 105():27-42. PubMed ID: 32616437
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease.
    Vogel JW; Iturria-Medina Y; Strandberg OT; Smith R; Levitis E; Evans AC; Hansson O; ;
    Nat Commun; 2020 May; 11(1):2612. PubMed ID: 32457389
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Visualization of PS/γ-Secretase Activity in Living Cells.
    Maesako M; Sekula NM; Aristarkhova A; Feschenko P; Anderson LC; Berezovska O
    iScience; 2020 Jun; 23(6):101139. PubMed ID: 32438286
    [TBL] [Abstract][Full Text] [Related]  

  • 26. γ-Secretase Partitioning into Lipid Bilayers Remodels Membrane Microdomains after Direct Insertion.
    Barros M; Houlihan WJ; Paresi CJ; Brendel M; Rynearson KD; Lee CW; Prikhodko O; Cregger C; Chang G; Wagner SL; Gilchrist ML; Li YM
    Langmuir; 2020 Jun; 36(23):6569-6579. PubMed ID: 32432881
    [TBL] [Abstract][Full Text] [Related]  

  • 27. γ-Secretase Activity Is Associated with Braak Senile Plaque Stages.
    Kakuda N; Yamaguchi H; Akazawa K; Hata S; Suzuki T; Hatsuta H; Murayama S; Funamoto S; Ihara Y
    Am J Pathol; 2020 Jun; 190(6):1323-1331. PubMed ID: 32201261
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Polarity Mapping of Cells and Embryos by Improved Fluorescent Solvatochromic Pyrene Probe.
    Valanciunaite J; Kempf E; Seki H; Danylchuk DI; Peyriéras N; Niko Y; Klymchenko AS
    Anal Chem; 2020 May; 92(9):6512-6520. PubMed ID: 32153188
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tau Propagation as a Diagnostic and Therapeutic Target for Dementia: Potentials and Unanswered Questions.
    Takeda S
    Front Neurosci; 2019; 13():1274. PubMed ID: 31920473
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
    Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
    Neuron; 2019 Dec; 104(5):1022. PubMed ID: 31805257
    [No Abstract]   [Full Text] [Related]  

  • 31. Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.
    Chen JJ; Nathaniel DL; Raghavan P; Nelson M; Tian R; Tse E; Hong JY; See SK; Mok SA; Hein MY; Southworth DR; Grinberg LT; Gestwicki JE; Leonetti MD; Kampmann M
    J Biol Chem; 2019 Dec; 294(50):18952-18966. PubMed ID: 31578281
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Smallest near-infrared fluorescent protein evolved from cyanobacteriochrome as versatile tag for spectral multiplexing.
    Oliinyk OS; Shemetov AA; Pletnev S; Shcherbakova DM; Verkhusha VV
    Nat Commun; 2019 Jan; 10(1):279. PubMed ID: 30655515
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease.
    Hung COY; Livesey FJ
    Cell Rep; 2018 Dec; 25(13):3647-3660.e2. PubMed ID: 30590039
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition.
    Pontecorvo MJ; Devous MD; Navitsky M; Lu M; Salloway S; Schaerf FW; Jennings D; Arora AK; McGeehan A; Lim NC; Xiong H; Joshi AD; Siderowf A; Mintun MA;
    Brain; 2017 Mar; 140(3):748-763. PubMed ID: 28077397
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.
    Lauritzen I; Pardossi-Piquard R; Bourgeois A; Pagnotta S; Biferi MG; Barkats M; Lacor P; Klein W; Bauer C; Checler F
    Acta Neuropathol; 2016 Aug; 132(2):257-276. PubMed ID: 27138984
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments.
    Meckler X; Checler F
    J Biol Chem; 2016 Jun; 291(24):12821-12837. PubMed ID: 27059953
    [TBL] [Abstract][Full Text] [Related]  

  • 37. γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).
    Lessard CB; Cottrell BA; Maruyama H; Suresh S; Golde TE; Koo EH
    PLoS One; 2015; 10(12):e0144758. PubMed ID: 26678856
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
    Pooler AM; Polydoro M; Maury EA; Nicholls SB; Reddy SM; Wegmann S; William C; Saqran L; Cagsal-Getkin O; Pitstick R; Beier DR; Carlson GA; Spires-Jones TL; Hyman BT
    Acta Neuropathol Commun; 2015 Mar; 3():14. PubMed ID: 25853174
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Alzheimer presenilin-1 mutations dramatically reduce trimming of long amyloid β-peptides (Aβ) by γ-secretase to increase 42-to-40-residue Aβ.
    Fernandez MA; Klutkowski JA; Freret T; Wolfe MS
    J Biol Chem; 2014 Nov; 289(45):31043-52. PubMed ID: 25239621
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase.
    Kanatsu K; Morohashi Y; Suzuki M; Kuroda H; Watanabe T; Tomita T; Iwatsubo T
    Nat Commun; 2014 Feb; 5():3386. PubMed ID: 24577224
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 4.