BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 36905915)

  • 41. The heterogeneous transition state of resistance to RET kinase inhibitors converges on ERK1/2-driven Aurora A/B kinases.
    Hu X; Liu X; Khatri U; Wu J
    Drug Resist Updat; 2023 May; 68():100958. PubMed ID: 36990046
    [TBL] [Abstract][Full Text] [Related]  

  • 42. RET rearrangements in non-small cell lung cancer: Evolving treatment landscape and future challenges.
    Servetto A; Esposito D; Ferrara R; Signorelli D; Belli S; Napolitano F; Santaniello A; Ciciola P; Formisano L; Bianco R
    Biochim Biophys Acta Rev Cancer; 2022 Nov; 1877(6):188810. PubMed ID: 36202311
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl)benzamides as novel RET kinase inhibitors.
    Han M; Li S; Ai J; Sheng R; Hu Y; Hu Y; Geng M
    Bioorg Med Chem Lett; 2016 Dec; 26(23):5679-5684. PubMed ID: 27815117
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Structure-Based Optimization of the Third Generation Type II Macrocycle TRK Inhibitors with Improved Activity against Solvent-Front, xDFG, and Gatekeeper Mutations.
    Wang Z; Wang J; Wang Y; Xiang S; Zhou H; Song S; Song X; Tu Z; Zhou Y; Ding K; Zhang ZM; Zhang Z; Lu X
    J Med Chem; 2023 Sep; 66(18):12950-12965. PubMed ID: 37676745
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Hallmarks of RET and Co-occuring Genomic Alterations in
    Adashek JJ; Desai AP; Andreev-Drakhlin AY; Roszik J; Cote GJ; Subbiah V
    Mol Cancer Ther; 2021 Oct; 20(10):1769-1776. PubMed ID: 34493590
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Machine learning driven drug repurposing strategy for identification of potential RET inhibitors against non-small cell lung cancer.
    Ramesh P; Karuppasamy R; Veerappapillai S
    Med Oncol; 2022 Dec; 40(1):56. PubMed ID: 36542155
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.
    Gautschi O; Milia J; Filleron T; Wolf J; Carbone DP; Owen D; Camidge R; Narayanan V; Doebele RC; Besse B; Remon-Masip J; Janne PA; Awad MM; Peled N; Byoung CC; Karp DD; Van Den Heuvel M; Wakelee HA; Neal JW; Mok TSK; Yang JCH; Ou SI; Pall G; Froesch P; Zalcman G; Gandara DR; Riess JW; Velcheti V; Zeidler K; Diebold J; Früh M; Michels S; Monnet I; Popat S; Rosell R; Karachaliou N; Rothschild SI; Shih JY; Warth A; Muley T; Cabillic F; Mazières J; Drilon A
    J Clin Oncol; 2017 May; 35(13):1403-1410. PubMed ID: 28447912
    [TBL] [Abstract][Full Text] [Related]  

  • 48. RET fusion gene: translation to personalized lung cancer therapy.
    Kohno T; Tsuta K; Tsuchihara K; Nakaoku T; Yoh K; Goto K
    Cancer Sci; 2013 Nov; 104(11):1396-400. PubMed ID: 23991695
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Alectinib activity in chemotherapy-refractory metastatic RET-rearranged non-small cell lung carcinomas: A case series.
    Ribeiro MFSA; Alessi JVM; Oliveira LJC; Gongora ABL; Sacardo KP; Zucchetti BM; Shimada AK; de Galiza Barbosa F; Feher O; Katz A
    Lung Cancer; 2020 Jan; 139():9-12. PubMed ID: 31698333
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Targeting the RET tyrosine kinase in neuroblastoma: A review and application of a novel selective drug design strategy.
    Steen EA; Basilaia M; Kim W; Getz T; Gustafson JL; Zage PE
    Biochem Pharmacol; 2023 Oct; 216():115751. PubMed ID: 37595672
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors.
    Wang C; Liu H; Song Z; Ji Y; Xing L; Peng X; Wang X; Ai J; Geng M; Zhang A
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2544-2548. PubMed ID: 28404375
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
    Plenker D; Riedel M; Brägelmann J; Dammert MA; Chauhan R; Knowles PP; Lorenz C; Keul M; Bührmann M; Pagel O; Tischler V; Scheel AH; Schütte D; Song Y; Stark J; Mrugalla F; Alber Y; Richters A; Engel J; Leenders F; Heuckmann JM; Wolf J; Diebold J; Pall G; Peifer M; Aerts M; Gevaert K; Zahedi RP; Buettner R; Shokat KM; McDonald NQ; Kast SM; Gautschi O; Thomas RK; Sos ML
    Sci Transl Med; 2017 Jun; 9(394):. PubMed ID: 28615362
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Antitumor Activity and Acquired Resistance Mechanism of Dovitinib (TKI258) in RET-Rearranged Lung Adenocarcinoma.
    Kang CW; Jang KW; Sohn J; Kim SM; Pyo KH; Kim H; Yun MR; Kang HN; Kim HR; Lim SM; Moon YW; Paik S; Kim DJ; Kim JH; Cho BC
    Mol Cancer Ther; 2015 Oct; 14(10):2238-48. PubMed ID: 26208525
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Emergence of RET rearrangement co-existing with activated EGFR mutation in EGFR-mutated NSCLC patients who had progressed on first- or second-generation EGFR TKI.
    Klempner SJ; Bazhenova LA; Braiteh FS; Nikolinakos PG; Gowen K; Cervantes CM; Chmielecki J; Greenbowe JR; Ross JS; Stephens PJ; Miller VA; Ali SM; Ou SH
    Lung Cancer; 2015 Sep; 89(3):357-9. PubMed ID: 26187428
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Targeting RET alterations in cancer: Recent progress and future directions.
    Shabbir A; Kojadinovic A; Shafiq T; Mundi PS
    Crit Rev Oncol Hematol; 2023 Jan; 181():103882. PubMed ID: 36481304
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Discovery, preclinical development, and clinical application of pralsetinib in the treatment of thyroid cancer.
    Locantore P; Novizio R; Corsello A; Paragliola RM; Pontecorvi A; Corsello SM
    Expert Opin Drug Discov; 2022 Feb; 17(2):101-107. PubMed ID: 34702125
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Design and development of photoswitchable DFG-Out RET kinase inhibitors.
    Xu Y; Gao C; Andreasson M; Håversen L; Carrasco MP; Fleming C; Lundbäck T; Andréasson J; Grøtli M
    Eur J Med Chem; 2022 Apr; 234():114226. PubMed ID: 35305461
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.
    Moccia M; Frett B; Zhang L; Lakkaniga NR; Briggs DC; Chauhan R; Brescia A; Federico G; Yan W; Santoro M; McDonald NQ; Li HY; Carlomagno F
    J Med Chem; 2020 May; 63(9):4506-4516. PubMed ID: 32298114
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach.
    Saha D; Ryan KR; Lakkaniga NR; Smith EL; Frett B
    ChemMedChem; 2021 May; 16(10):1605-1608. PubMed ID: 33559353
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Identification and Development of 1,4-Diaryl-1,2,3-triazolo-Based Ureas as Novel FLT3 Inhibitors.
    Liu J; Wang Y; Chen C; Tu Z; Zhu S; Zhou F; Si H; Zheng C; Zhang Z; Cai Q
    ACS Med Chem Lett; 2020 Aug; 11(8):1567-1572. PubMed ID: 32832025
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.