Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 36907105)

  • 1. Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence.
    Fuentes-Fayos AC; G-García ME; Pérez-Gómez JM; Montero-Hidalgo AJ; Martín-Colom J; Doval-Rosa C; Blanco-Acevedo C; Torres E; Toledano-Delgado Á; Sánchez-Sánchez R; Peralbo-Santaella E; Ortega-Salas RM; Jiménez-Vacas JM; Tena-Sempere M; López M; Castaño JP; Gahete MD; Solivera J; Luque RM
    EBioMedicine; 2023 Apr; 90():104484. PubMed ID: 36907105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Clinical, Cellular, and Molecular Evidence of the Additive Antitumor Effects of Biguanides and Statins in Prostate Cancer.
    Jiménez-Vacas JM; Herrero-Aguayo V; Montero-Hidalgo AJ; Sáez-Martínez P; Gómez-Gómez E; León-González AJ; Fuentes-Fayos AC; Yubero-Serrano EM; Requena-Tapia MJ; López M; Castaño JP; Gahete MD; Luque RM
    J Clin Endocrinol Metab; 2021 Jan; 106(2):e696-e710. PubMed ID: 33247590
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3.
    Fuentes-Fayos AC; Vázquez-Borrego MC; Jiménez-Vacas JM; Bejarano L; Pedraza-Arévalo S; L-López F; Blanco-Acevedo C; Sánchez-Sánchez R; Reyes O; Ventura S; Solivera J; Breunig JJ; Blasco MA; Gahete MD; Castaño JP; Luque RM
    Brain; 2020 Dec; 143(11):3273-3293. PubMed ID: 33141183
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances.
    Fuentes-Fayos AC; Pérez-Gómez JM; G-García ME; Jiménez-Vacas JM; Blanco-Acevedo C; Sánchez-Sánchez R; Solivera J; Breunig JJ; Gahete MD; Castaño JP; Luque RM
    J Exp Clin Cancer Res; 2022 Jan; 41(1):39. PubMed ID: 35086552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Statins Directly Regulate Pituitary Cell Function and Exert Antitumor Effects in Pituitary Tumors.
    Vázquez-Borrego MC; Fuentes-Fayos AC; Herrera-Martínez AD; Venegas-Moreno E; L-López F; Fanciulli A; Moreno-Moreno P; Alhambra-Expósito MR; Barrera-Martín A; Dios E; Blanco-Acevedo C; Solivera J; Granata R; Kineman RD; Gahete MD; Soto-Moreno A; Gálvez-Moreno MA; Castaño JP; Luque RM
    Neuroendocrinology; 2020; 110(11-12):1028-1041. PubMed ID: 31940630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo.
    Nakabayashi H; Shimizu K
    BMC Cancer; 2012 Oct; 12():453. PubMed ID: 23039130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.
    Kochuparambil ST; Al-Husein B; Goc A; Soliman S; Somanath PR
    J Pharmacol Exp Ther; 2011 Feb; 336(2):496-505. PubMed ID: 21059805
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.
    Würth R; Pattarozzi A; Gatti M; Bajetto A; Corsaro A; Parodi A; Sirito R; Massollo M; Marini C; Zona G; Fenoglio D; Sambuceti G; Filaci G; Daga A; Barbieri F; Florio T
    Cell Cycle; 2013 Jan; 12(1):145-56. PubMed ID: 23255107
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcriptional Regulation of
    Buist M; Fuss D; Rastegar M
    Biomolecules; 2021 Aug; 11(8):. PubMed ID: 34439919
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Restoration of alveolar type II cell function contributes to simvastatin-induced attenuation of lung ischemia-reperfusion injury.
    Wu Y; Lv J; Feng D; Jiang F; Fan X; Zhang Z; Yin R; Xu L
    Int J Mol Med; 2012 Dec; 30(6):1294-306. PubMed ID: 23076613
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.
    Zheng Y; McFarland BC; Drygin D; Yu H; Bellis SL; Kim H; Bredel M; Benveniste EN
    Clin Cancer Res; 2013 Dec; 19(23):6484-94. PubMed ID: 24036851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simvastatin Up-Regulates Annexin A10 That Can Inhibit the Proliferation, Migration, and Invasion in Androgen-Independent Human Prostate Cancer Cells.
    Miyazawa Y; Sekine Y; Kato H; Furuya Y; Koike H; Suzuki K
    Prostate; 2017 Mar; 77(4):337-349. PubMed ID: 27862098
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.
    Lee JE; Lim JH; Hong YK; Yang SH
    Cancer Res Treat; 2018 Oct; 50(4):1331-1342. PubMed ID: 29334602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of simvastatin and metformin on inflammation and insulin resistance in individuals with mild metabolic syndrome.
    Bulcão C; Ribeiro-Filho FF; Sañudo A; Roberta Ferreira SG
    Am J Cardiovasc Drugs; 2007; 7(3):219-24. PubMed ID: 17610348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice.
    Cho SJ; Kim JS; Kim JM; Lee JY; Jung HC; Song IS
    Int J Cancer; 2008 Aug; 123(4):951-7. PubMed ID: 18521906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanistic Study of Inhibitory Effects of Metformin and Atorvastatin in Combination on Prostate Cancer Cells in Vitro and in Vivo.
    Wang ZS; Huang HR; Zhang LY; Kim S; He Y; Li DL; Farischon C; Zhang K; Zheng X; Du ZY; Goodin S
    Biol Pharm Bull; 2017; 40(8):1247-1254. PubMed ID: 28769006
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway.
    Kodach LL; Bleuming SA; Peppelenbosch MP; Hommes DW; van den Brink GR; Hardwick JC
    Gastroenterology; 2007 Oct; 133(4):1272-81. PubMed ID: 17919499
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HMG-CoA reductase inhibition causes increased necrosis and apoptosis in an in vivo mouse glioblastoma multiforme model.
    Bababeygy SR; Polevaya NV; Youssef S; Sun A; Xiong A; Prugpichailers T; Veeravagu A; Hou LC; Steinman L; Tse V
    Anticancer Res; 2009 Dec; 29(12):4901-8. PubMed ID: 20044596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effects of metformin and simvastatin on the growth of LNCaP and RWPE-1 prostate epithelial cell lines.
    Pennanen P; Syvälä H; Bläuer M; Savinainen K; Ylikomi T; Tammela TLJ; Murtola TJ
    Eur J Pharmacol; 2016 Oct; 788():160-167. PubMed ID: 27341997
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
    Sesen J; Dahan P; Scotland SJ; Saland E; Dang VT; Lemarié A; Tyler BM; Brem H; Toulas C; Cohen-Jonathan Moyal E; Sarry JE; Skuli N
    PLoS One; 2015; 10(4):e0123721. PubMed ID: 25867026
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.