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2. Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes. Pereira L; Rehmann H; Lao DH; Erickson JR; Bossuyt J; Chen J; Bers DM Proc Natl Acad Sci U S A; 2015 Mar; 112(13):3991-6. PubMed ID: 25829540 [TBL] [Abstract][Full Text] [Related]
3. Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice. Prajapati R; Fujita T; Suita K; Nakamura T; Cai W; Hidaka Y; Umemura M; Yokoyama U; Knollmann BC; Okumura S; Ishikawa Y Circ J; 2019 Jan; 83(2):295-303. PubMed ID: 30518738 [TBL] [Abstract][Full Text] [Related]
4. Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet. Virwani PD; Cai L; Yeung PKK; Qian G; Chen Y; Zhou L; Wong JWH; Wang Y; Ho JWK; Lau KK; Qian PY; Chung SK Microbiome; 2022 Nov; 10(1):187. PubMed ID: 36329549 [TBL] [Abstract][Full Text] [Related]
6. Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling. Edland F; Wergeland A; Kopperud R; Åsrud KS; Hoivik EA; Witsø SL; Æsøy R; Madsen L; Kristiansen K; Bakke M; Døskeland SO; Jonassen AK Nutr Metab (Lond); 2016; 13():87. PubMed ID: 27933093 [TBL] [Abstract][Full Text] [Related]
7. Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress. Laudette M; Coluccia A; Sainte-Marie Y; Solari A; Fazal L; Sicard P; Silvestri R; Mialet-Perez J; Pons S; Ghaleh B; Blondeau JP; Lezoualc'h F Cardiovasc Res; 2019 Oct; 115(12):1766-1777. PubMed ID: 30873562 [TBL] [Abstract][Full Text] [Related]
8. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). Courilleau D; Bouyssou P; Fischmeister R; Lezoualc'h F; Blondeau JP Biochem Biophys Res Commun; 2013 Oct; 440(3):443-8. PubMed ID: 24099776 [TBL] [Abstract][Full Text] [Related]
9. Exchange-protein activated by cAMP (EPAC) regulates L-type calcium channel in atrial fibrillation of heart failure model. Zhang MX; Zheng JK; Wang WW; Kong FQ; Wu XX; Jiang JK; Pan JX Eur Rev Med Pharmacol Sci; 2019 Mar; 23(5):2200-2207. PubMed ID: 30915767 [TBL] [Abstract][Full Text] [Related]
10. The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons. Tong J; Liu X; Vickstrom C; Li Y; Yu L; Lu Y; Smrcka AV; Liu QS J Neurosci; 2017 Mar; 37(11):3030-3044. PubMed ID: 28209735 [TBL] [Abstract][Full Text] [Related]
11. Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements. Mediero A; Perez-Aso M; Cronstein BN FASEB J; 2014 Nov; 28(11):4901-13. PubMed ID: 25122553 [TBL] [Abstract][Full Text] [Related]
12. Epac Signaling Is Required for Cocaine-Induced Change in AMPA Receptor Subunit Composition in the Ventral Tegmental Area. Liu X; Chen Y; Tong J; Reynolds AM; Proudfoot SC; Qi J; Penzes P; Lu Y; Liu QS J Neurosci; 2016 Apr; 36(17):4802-15. PubMed ID: 27122037 [TBL] [Abstract][Full Text] [Related]
14. Exchange protein activated by cyclic-adenosine monophosphate (Epac) regulates atrial fibroblast function and controls cardiac remodelling. Surinkaew S; Aflaki M; Takawale A; Chen Y; Qi XY; Gillis MA; Shi YF; Tardif JC; Chattipakorn N; Nattel S Cardiovasc Res; 2019 Jan; 115(1):94-106. PubMed ID: 30016400 [TBL] [Abstract][Full Text] [Related]
15. Urinary concentrating defect in mice lacking Epac1 or Epac2. Cherezova A; Tomilin V; Buncha V; Zaika O; Ortiz PA; Mei F; Cheng X; Mamenko M; Pochynyuk O FASEB J; 2019 Feb; 33(2):2156-2170. PubMed ID: 30252533 [TBL] [Abstract][Full Text] [Related]
16. Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis. Ni Z; Cheng X Cells; 2021 Oct; 10(10):. PubMed ID: 34685730 [TBL] [Abstract][Full Text] [Related]
17. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells. Roscioni SS; Kistemaker LE; Menzen MH; Elzinga CR; Gosens R; Halayko AJ; Meurs H; Schmidt M Respir Res; 2009 Sep; 10(1):88. PubMed ID: 19788733 [TBL] [Abstract][Full Text] [Related]
19. Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs. de Rooij J; Rehmann H; van Triest M; Cool RH; Wittinghofer A; Bos JL J Biol Chem; 2000 Jul; 275(27):20829-36. PubMed ID: 10777494 [TBL] [Abstract][Full Text] [Related]