These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 36914634)

  • 1. Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
    Dahlin JL; Hua BK; Zucconi BE; Nelson SD; Singh S; Carpenter AE; Shrimp JH; Lima-Fernandes E; Wawer MJ; Chung LPW; Agrawal A; O'Reilly M; Barsyte-Lovejoy D; Szewczyk M; Li F; Lak P; Cuellar M; Cole PA; Meier JL; Thomas T; Baell JB; Brown PJ; Walters MA; Clemons PA; Schreiber SL; Wagner BK
    Nat Commun; 2023 Mar; 14(1):1364. PubMed ID: 36914634
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Redox active or thiol reactive? Optimization of rapid screens to identify less evident nuisance compounds.
    Proj M; Knez D; Sosič I; Gobec S
    Drug Discov Today; 2022 Jun; 27(6):1733-1742. PubMed ID: 35301150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity.
    Fredin Haslum J; Lardeau CH; Karlsson J; Turkki R; Leuchowius KJ; Smith K; Müllers E
    Nat Commun; 2024 Apr; 15(1):3470. PubMed ID: 38658534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuisance compounds in cellular assays.
    Dahlin JL; Auld DS; Rothenaigner I; Haney S; Sexton JZ; Nissink JWM; Walsh J; Lee JA; Strelow JM; Willard FS; Ferrins L; Baell JB; Walters MA; Hua BK; Hadian K; Wagner BK
    Cell Chem Biol; 2021 Mar; 28(3):356-370. PubMed ID: 33592188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay.
    Willis C; Nyffeler J; Harrill J
    SLAS Discov; 2020 Aug; 25(7):755-769. PubMed ID: 32546035
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening.
    Wigle TJ; Swinger KK; Campbell JE; Scholle MD; Sherrill J; Admirand EA; Boriack-Sjodin PA; Kuntz KW; Chesworth R; Moyer MP; Scott MP; Copeland RA
    J Biomol Screen; 2015 Jul; 20(6):810-20. PubMed ID: 25755264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells.
    Kallal LA; Waszkiewicz A; Jaworski JP; Della Pietra A; Berrodin T; Brady P; Jurewicz AJ; Zeng X; Payne L; Medina JR; Doepner-Buser C; Mangatt B
    SLAS Discov; 2021 Feb; 26(2):216-229. PubMed ID: 33482073
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Utilising acoustic mist ionisation mass spectrometry to identify redox cycling compounds in high throughput screening outputs.
    Moore R; Molyneux C; Sinclair I; Holdgate GA; Walsh J
    SLAS Discov; 2022 Sep; 27(6):369-374. PubMed ID: 35753605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds.
    Akbarzadeh M; Deipenwisch I; Schoelermann B; Pahl A; Sievers S; Ziegler S; Waldmann H
    Cell Chem Biol; 2022 Jun; 29(6):1053-1064.e3. PubMed ID: 34968420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers.
    Martin HL; Adams M; Higgins J; Bond J; Morrison EE; Bell SM; Warriner S; Nelson A; Tomlinson DC
    PLoS One; 2014; 9(2):e88338. PubMed ID: 24505478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns.
    Rothenaigner I; Hadian K
    SLAS Discov; 2021 Aug; 26(7):851-854. PubMed ID: 33882754
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K; Watt ED; Hornung MW; Hedge JM; Judson RS; Crofton KM; Houck KA; Simmons SO
    Toxicol Sci; 2016 May; 151(1):160-80. PubMed ID: 26884060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data.
    Nyffeler J; Haggard DE; Willis C; Setzer RW; Judson R; Paul-Friedman K; Everett LJ; Harrill JA
    SLAS Discov; 2021 Feb; 26(2):292-308. PubMed ID: 32862757
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Utility of Resazurin, Horseradish Peroxidase, and NMR Assays to Identify Redox-Related False-Positive Behavior in High-Throughput Screens.
    Tarnowski M; Barozet A; Johansson C; Eriksson PO; Engkvist O; Walsh J; Nissink JWM
    Assay Drug Dev Technol; 2018 Apr; 16(3):171-191. PubMed ID: 29608094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Communication of Hit Quality Using Natural History Visualizations (NHVs).
    Nelson KM; Walters MA
    SLAS Discov; 2021 Aug; 26(7):862-869. PubMed ID: 34111995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents.
    Johnston PA; Soares KM; Shinde SN; Foster CA; Shun TY; Takyi HK; Wipf P; Lazo JS
    Assay Drug Dev Technol; 2008 Aug; 6(4):505-18. PubMed ID: 18699726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiparametric High-Content Assays to Measure Cell Health and Oxidative Damage as a Model for Drug-Induced Liver Injury.
    Pohan G; Espinosa JA; Chen S; Ang KK; Arkin MR; Markossian S
    Curr Protoc Chem Biol; 2020 Dec; 12(4):e90. PubMed ID: 33315311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Action plan for hit identification (APHID): KAT6A as a case study.
    Yi X; Xue L; Thomas T; Baell JB
    Future Med Chem; 2020 Mar; 12(5):423-437. PubMed ID: 32064938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biophysics: for HTS hit validation, chemical lead optimization, and beyond.
    Genick CC; Wright SK
    Expert Opin Drug Discov; 2017 Sep; 12(9):897-907. PubMed ID: 28658992
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell painting transfer increases screening hit rate.
    Cohen E; Corbe M; Franco CA; Vasconcelos FF; Perez F; Del Nery E; Bollot G; Genovesio A
    Biol Imaging; 2023; 3():e4. PubMed ID: 38487691
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.