BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 36921275)

  • 21. MDM2 antagonist can inhibit tumor growth in hepatocellular carcinoma with different types of p53 in vitro.
    Wang J; Zheng T; Chen X; Song X; Meng X; Bhatta N; Pan S; Jiang H; Liu L
    J Gastroenterol Hepatol; 2011 Feb; 26(2):371-7. PubMed ID: 21261729
    [TBL] [Abstract][Full Text] [Related]  

  • 22. In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
    Wang W; Rayburn ER; Velu SE; Nadkarni DH; Murugesan S; Zhang R
    Clin Cancer Res; 2009 May; 15(10):3511-8. PubMed ID: 19451594
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.
    Ling X; Cao S; Cheng Q; Keefe JT; Rustum YM; Li F
    PLoS One; 2012; 7(9):e45571. PubMed ID: 23029106
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone.
    Altenburg JD; Bieberich AA; Terry C; Harvey KA; Vanhorn JF; Xu Z; Jo Davisson V; Siddiqui RA
    BMC Cancer; 2011 Apr; 11():149. PubMed ID: 21510869
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase pathways.
    Nieves-Neira W; Pommier Y
    Int J Cancer; 1999 Jul; 82(3):396-404. PubMed ID: 10399957
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer.
    Shi Y; Xu S; Li S
    Mol Cell Endocrinol; 2022 Apr; 545():111558. PubMed ID: 35033575
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
    Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Overexpression of DJ-1 enhances colorectal cancer cell proliferation through the cyclin-D1/MDM2-p53 signaling pathway.
    Zhu X; Luo C; Lin K; Bu F; Ye F; Huang C; Luo H; Huang J; Zhu Z
    Biosci Trends; 2020 May; 14(2):83-95. PubMed ID: 32132307
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Small Molecule Inhibition of MDM2-p53 Interaction Augments Radiation Response in Human Tumors.
    Werner LR; Huang S; Francis DM; Armstrong EA; Ma F; Li C; Iyer G; Canon J; Harari PM
    Mol Cancer Ther; 2015 Sep; 14(9):1994-2003. PubMed ID: 26162687
    [TBL] [Abstract][Full Text] [Related]  

  • 30. MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.
    Feng FY; Zhang Y; Kothari V; Evans JR; Jackson WC; Chen W; Johnson SB; Luczak C; Wang S; Hamstra DA
    Neoplasia; 2016 Apr; 18(4):213-22. PubMed ID: 27108384
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design and Synthesis of Novel Celecoxib Analogues with Potential Cytotoxic and Pro-apoptotic Activity against Breast Cancer Cell Line MCF-7.
    Abdelhaleem EF; Kassab AE; El-Nassan HB; Khalil OM
    Med Chem; 2022; 18(8):903-914. PubMed ID: 35264093
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models.
    Diamond JR; Eckhardt SG; Tan AC; Newton TP; Selby HM; Brunkow KL; Kachaeva MI; Varella-Garcia M; Pitts TM; Bray MR; Fletcher GC; Tentler JJ
    Clin Cancer Res; 2013 Jan; 19(1):291-303. PubMed ID: 23136197
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Co-delivery of p53 and MDM2 inhibitor RG7388 using a hydroxyl terminal PAMAM dendrimer derivative for synergistic cancer therapy.
    Chen K; Xin X; Qiu L; Li W; Guan G; Li G; Qiao M; Zhao X; Hu H; Chen D
    Acta Biomater; 2019 Dec; 100():118-131. PubMed ID: 31568878
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies.
    Abd El-Wahab HAA; Mansour HS; Ali AM; El-Awady R; Aboul-Fadl T
    Bioorg Chem; 2022 Mar; 120():105622. PubMed ID: 35091290
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Potential antitumor agent from the endophytic fungus Pestalotiopsis photiniae induces apoptosis via the mitochondrial pathway in HeLa cells.
    Chen C; Hu SY; Luo DQ; Zhu SY; Zhou CQ
    Oncol Rep; 2013 Oct; 30(4):1773-81. PubMed ID: 23863966
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dichloromethane fraction of Moringa oleifera leaf methanolic extract selectively inhibits breast cancer cells (MCF7) by induction of apoptosis via upregulation of Bax, p53 and caspase 8 expressions.
    Mohd Fisall UF; Ismail NZ; Adebayo IA; Arsad H
    Mol Biol Rep; 2021 May; 48(5):4465-4475. PubMed ID: 34086162
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53.
    Ho TF; Ma CJ; Lu CH; Tsai YT; Wei YH; Chang JS; Lai JK; Cheuh PJ; Yeh CT; Tang PC; Tsai Chang J; Ko JL; Liu FS; Yen HE; Chang CC
    Toxicol Appl Pharmacol; 2007 Dec; 225(3):318-28. PubMed ID: 17881028
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.
    Wang S; Liu Q; Zhang Y; Liu K; Yu P; Liu K; Luan J; Duan H; Lu Z; Wang F; Wu E; Yagasaki K; Zhang G
    Mol Cancer; 2009 Oct; 8():81. PubMed ID: 19796390
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway.
    Wan W; Hou Y; Wang K; Cheng Y; Pu X; Ye X
    Cell Death Dis; 2019 Mar; 10(3):248. PubMed ID: 30867411
    [TBL] [Abstract][Full Text] [Related]  

  • 40. New orally active DNA minor groove binding small molecule CT-1 acts against breast cancer by targeting tumor DNA damage leading to p53-dependent apoptosis.
    Saini KS; Hamidullah ; Ashraf R; Mandalapu D; Das S; Siddiqui MQ; Dwivedi S; Sarkar J; Sharma VL; Konwar R
    Mol Carcinog; 2017 Apr; 56(4):1266-1280. PubMed ID: 27813185
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.