These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 3694493)

  • 1. Competition between two enzymes for substrate removal in liver: modulating effects due to substrate recruitment of hepatocyte activity.
    Morris ME; Pang KS
    J Pharmacokinet Biopharm; 1987 Oct; 15(5):473-96. PubMed ID: 3694493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nonlinear protein binding and enzyme heterogeneity: effects on hepatic drug removal.
    Xu X; Selick P; Pang KS
    J Pharmacokinet Biopharm; 1993 Feb; 21(1):43-74. PubMed ID: 8410683
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatic modeling of metabolite kinetics in sequential and parallel pathways: salicylamide and gentisamide metabolism in perfused rat liver.
    Xu X; Pang KS
    J Pharmacokinet Biopharm; 1989 Dec; 17(6):645-71. PubMed ID: 2635738
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatic conjugation/deconjugation cycling pathways. Computer simulations examining the effect of Michaelis-Menten parameters, enzyme distribution patterns, and a diffusional barrier on metabolite disposition.
    Hansel SB; Morris ME
    J Pharmacokinet Biopharm; 1996 Apr; 24(2):219-43. PubMed ID: 8875348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Competing pathways in drug metabolism. II. An identical, anterior enzymic distribution for 2- and 5-sulfoconjugation and a posterior localization for 5-glucuronidation of gentisamide in the rat liver.
    Morris ME; Yuen V; Pang KS
    J Pharmacokinet Biopharm; 1988 Dec; 16(6):633-56. PubMed ID: 3251033
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Normal and retrograde perfusion to probe the zonal distribution of sulfation and glucuronidation activities of harmol in the perfused rat liver preparation.
    Pang KS; Koster H; Halsema IC; Scholtens E; Mulder GJ; Stillwell RN
    J Pharmacol Exp Ther; 1983 Mar; 224(3):647-53. PubMed ID: 6827487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Competing pathways in drug metabolism. I. Effect of input concentration on the conjugation of gentisamide in the once-through in situ perfused rat liver preparation.
    Morris ME; Yuen V; Tang BK; Pang KS
    J Pharmacol Exp Ther; 1988 May; 245(2):614-24. PubMed ID: 3367309
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetics of sulfation and glucuronidation of harmol in the perfused rat liver preparation. Disappearance of aberrances in glucuronidation kinetics by inhibition of sulfation.
    Koster H; Halsema I; Scholtens E; Pang KS; Mulder GJ
    Biochem Pharmacol; 1982 Oct; 31(19):3023-8. PubMed ID: 7150332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Altered AZT (3'-azido-3'-deoxythymidine) glucuronidation kinetics in liver microsomes as an explanation for underprediction of in vivo clearance: comparison to hepatocytes and effect of incubation environment.
    Engtrakul JJ; Foti RS; Strelevitz TJ; Fisher MB
    Drug Metab Dispos; 2005 Nov; 33(11):1621-7. PubMed ID: 16049128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of acetaminophen sulfation by 2,6-dichloro-4-nitrophenol in the perfused rat liver preparation. Lack of a compensatory increase of glucuronidation.
    Fayz S; Cherry WF; Dawson JR; Mulder GJ; Pang KS
    Drug Metab Dispos; 1984; 12(3):323-9. PubMed ID: 6145559
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequential metabolism of salicylamide exclusively to gentisamide 5-glucuronide and not gentisamide sulfate conjugates in single-pass in situ perfused rat liver.
    Xu X; Tang BK; Pang KS
    J Pharmacol Exp Ther; 1990 Jun; 253(3):965-73. PubMed ID: 2359032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Systematic studies of sulfation and glucuronidation of 12 flavonoids in the mouse liver S9 fraction reveal both unique and shared positional preferences.
    Tang L; Zhou J; Yang CH; Xia BJ; Hu M; Liu ZQ
    J Agric Food Chem; 2012 Mar; 60(12):3223-33. PubMed ID: 22352802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apparent aberrancy in the kinetics of intracellular metabolism of a single substrate by two enzymes. An alternative explanation for anomalies in the kinetics of sulfation and glucuronidation.
    Koster H; Mulder GJ
    Drug Metab Dispos; 1982; 10(4):330-5. PubMed ID: 6126330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kinetics of sulfation in the rat in vivo and in the perfused rat liver.
    Mulder GJ
    Fed Proc; 1986 Jul; 45(8):2229-34. PubMed ID: 3087784
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.
    Pritchard M; Fournel-Gigleux S; Siest G; Mackenzie P; Magdalou J
    Mol Pharmacol; 1994 Jan; 45(1):42-50. PubMed ID: 8302279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase II metabolism of betulin by rat and human UDP-glucuronosyltransferases and sulfotransferases.
    Hu Z; Wang Z; Luo S; James MO; Wang Y
    Chem Biol Interact; 2019 Apr; 302():190-195. PubMed ID: 30776358
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alteration of transit time and direction of flow to probe the heterogeneous distribution of conjugating activities for harmol in the perfused rat liver preparation.
    Dawson JR; Weitering JG; Mulder GJ; Stillwell RN; Pang KS
    J Pharmacol Exp Ther; 1985 Sep; 234(3):691-7. PubMed ID: 4032287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation.
    Riches Z; Bloomer J; Patel A; Nolan A; Coughtrie M
    Xenobiotica; 2009 May; 39(5):374-81. PubMed ID: 19280384
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of glucuronidation of benzo(a)pyrene phenols by long-chain fatty acids.
    Zhong Z; Kauffman FC; Thurman RG
    Cancer Res; 1991 Sep; 51(17):4511-5. PubMed ID: 1908348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interindividual variability in 2-hydroxylation, 3-sulfation, and 3-glucuronidation of ethynylestradiol in human liver.
    Shiraga T; Niwa T; Ohno Y; Kagayama A
    Biol Pharm Bull; 2004 Dec; 27(12):1900-6. PubMed ID: 15577203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.