BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 36945520)

  • 1. Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells.
    Gowans FA; Thach DQ; Wang Y; Altamirano Poblano BE; Dovala D; Tallarico JA; McKenna JM; Schirle M; Maimone TJ; Nomura DK
    bioRxiv; 2023 Mar; ():. PubMed ID: 36945520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells.
    Gowans FA; Thach DQ; Zhu Z; Wang Y; Altamirano Poblano BE; Dovala D; Tallarico JA; McKenna JM; Schirle M; Maimone TJ; Nomura DK
    ACS Chem Biol; 2024 Jun; 19(6):1260-1270. PubMed ID: 38739449
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemoproteomic Profiling Reveals that Anticancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.
    Belcher BP; Machicao PA; Tong B; Ho E; Friedli J; So B; Bui H; Isobe Y; Maimone TJ; Nomura DK
    Chembiochem; 2023 Jul; 24(14):e202300111. PubMed ID: 36964942
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemoproteomic Profiling Reveals that Anti-Cancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.
    Belcher BP; Machicao PA; Tong B; Ho E; Friedli J; So B; Bui H; Isobe Y; Maimone TJ; Nomura DK
    bioRxiv; 2023 Feb; ():. PubMed ID: 36798342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products.
    Grossman EA; Ward CC; Spradlin JN; Bateman LA; Huffman TR; Miyamoto DK; Kleinman JI; Nomura DK
    Cell Chem Biol; 2017 Nov; 24(11):1368-1376.e4. PubMed ID: 28919038
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.
    Chidley C; Trauger SA; Birsoy K; O'Shea EK
    Elife; 2016 Jul; 5():. PubMed ID: 27403889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.
    Berdan CA; Ho R; Lehtola HS; To M; Hu X; Huffman TR; Petri Y; Altobelli CR; Demeulenaere SG; Olzmann JA; Maimone TJ; Nomura DK
    Cell Chem Biol; 2019 Jul; 26(7):1027-1035.e22. PubMed ID: 31080076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysine-Targeted Inhibitors and Chemoproteomic Probes.
    Cuesta A; Taunton J
    Annu Rev Biochem; 2019 Jun; 88():365-381. PubMed ID: 30633551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A.
    Reisenauer KN; Tao Y; Das P; Song S; Svatek H; Patel SD; Mikhail S; Ingros A; Sheesley P; Masi M; Boari A; Evidente A; Kornienko A; Romo D; Taube J
    Sci Rep; 2021 May; 11(1):10652. PubMed ID: 34017048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Advances in applications of activity-based chemical probes in the characterization of amino acid reactivities].
    Li J; Wang G; Ye M; Qin H
    Se Pu; 2023 Jan; 41(1):14-23. PubMed ID: 36633073
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.
    Bury M; Novo-Uzal E; Andolfi A; Cimini S; Wauthoz N; Heffeter P; Lallemand B; Avolio F; Delporte C; Cimmino A; Dubois J; Van Antwerpen P; Zonno MC; Vurro M; Poumay Y; Berger W; Evidente A; De Gara L; Kiss R; Locato V
    Int J Oncol; 2013 Aug; 43(2):575-85. PubMed ID: 23754298
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms.
    Medina-Cleghorn D; Bateman LA; Ford B; Heslin A; Fisher KJ; Dalvie ED; Nomura DK
    Chem Biol; 2015 Oct; 22(10):1394-405. PubMed ID: 26496688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function.
    Ye Z; Zhang X; Zhu Y; Song T; Chen X; Lei X; Wang C
    Mol Pharm; 2018 Jun; 15(6):2413-2422. PubMed ID: 29763317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway.
    Abegg D; Tomanik M; Qiu N; Pechalrieu D; Shuster A; Commare B; Togni A; Herzon SB; Adibekian A
    J Am Chem Soc; 2021 Dec; 143(48):20332-20342. PubMed ID: 34817176
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes.
    Pósa A; Szabó R; Szalai Z; Kupai K; Deim Z; Murlasits Z; Bencsik O; Szekeres A; Vágvölgyi C; Balogh L; Juhász B; Szilvássy Z; Varga C
    Hum Exp Toxicol; 2017 Jun; 36(6):594-602. PubMed ID: 27402683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial protein OPA mediates osteoporosis induced by radiation through the P38 signaling pathway.
    Wang WD; Kang WB; Zhou XQ; Yao GF; Wang XJ
    Eur Rev Med Pharmacol Sci; 2018 Dec; 22(23):8091-8097. PubMed ID: 30556844
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiplexed Thiol Reactivity Profiling for Target Discovery of Electrophilic Natural Products.
    Tian C; Sun R; Liu K; Fu L; Liu X; Zhou W; Yang Y; Yang J
    Cell Chem Biol; 2017 Nov; 24(11):1416-1427.e5. PubMed ID: 28988947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system.
    Hall A; Larsen AK; Parhamifar L; Meyle KD; Wu LP; Moghimi SM
    Biochim Biophys Acta; 2013 Oct; 1827(10):1213-25. PubMed ID: 23850549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells.
    Wang MR; He JY; He JX; Liu KK; Yang J
    Chem Sci; 2021 Nov; 12(43):14557-14563. PubMed ID: 34881007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells.
    Rodolfo C; Rocco M; Cattaneo L; Tartaglia M; Sassi M; Aducci P; Scaloni A; Camoni L; Marra M
    PLoS One; 2016; 11(12):e0167672. PubMed ID: 27936075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.