These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 36966244)

  • 1. TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.
    Winfree RL; Seto M; Dumitrescu L; Menon V; De Jager P; Wang Y; Schneider J; Bennett DA; Jefferson AL; Hohman TJ
    Acta Neuropathol; 2023 Jun; 145(6):733-747. PubMed ID: 36966244
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease.
    Nguyen AT; Wang K; Hu G; Wang X; Miao Z; Azevedo JA; Suh E; Van Deerlin VM; Choi D; Roeder K; Li M; Lee EB
    Acta Neuropathol; 2020 Oct; 140(4):477-493. PubMed ID: 32840654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer's disease.
    Toomey CE; Heywood W; Benson BC; Packham G; Mills K; Lashley T
    Brain Pathol; 2020 Jul; 30(4):794-810. PubMed ID: 32267026
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Variants in the MS4A cluster interact with soluble TREM2 expression on biomarkers of neuropathology.
    Winfree RL; Nolan E; Dumitrescu L; Blennow K; Zetterberg H; Gifford KA; Pechman KR; Seto M; Petyuk VA; Wang Y; Schneider J; Bennett DA; Jefferson AL; Hohman TJ;
    Mol Neurodegener; 2024 May; 19(1):41. PubMed ID: 38760857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microglial activation, tau and amyloid deposition in TREM2 p.R47H carriers and mild cognitive impairment patients: a multi-modal/multi-tracer PET/MRI imaging study with influenza vaccine immune challenge.
    Cousins O; Schubert JJ; Chandra A; Veronese M; Valkimadi P; Creese B; Khan Z; Arathimos R; Hampshire A; Rosenzweig I; Ballard C; Corbett A; Aasland D; Velayudhan L; O'Neill M; Collier D; Awais R; Sander K; Årstad E; Howes O; Turkheimer F; Hodges A
    J Neuroinflammation; 2023 Nov; 20(1):272. PubMed ID: 37990275
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples.
    Prokop S; Miller KR; Labra SR; Pitkin RM; Hoxha K; Narasimhan S; Changolkar L; Rosenbloom A; Lee VM; Trojanowski JQ
    Acta Neuropathol; 2019 Oct; 138(4):613-630. PubMed ID: 31350575
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
    Lee SH; Meilandt WJ; Xie L; Gandham VD; Ngu H; Barck KH; Rezzonico MG; Imperio J; Lalehzadeh G; Huntley MA; Stark KL; Foreman O; Carano RAD; Friedman BA; Sheng M; Easton A; Bohlen CJ; Hansen DV
    Neuron; 2021 Apr; 109(8):1283-1301.e6. PubMed ID: 33675684
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of TREM2 in Alzheimer's Disease and its Consequences on β- Amyloid, Tau and Neurofibrillary Tangles.
    Singh AK; Mishra G; Maurya A; Awasthi R; Kumari K; Thakur A; Rai A; Rai GK; Sharma B; Kulkarni GT; Singh SK
    Curr Alzheimer Res; 2019; 16(13):1216-1229. PubMed ID: 31481003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
    Griciuc A; Patel S; Federico AN; Choi SH; Innes BJ; Oram MK; Cereghetti G; McGinty D; Anselmo A; Sadreyev RI; Hickman SE; El Khoury J; Colonna M; Tanzi RE
    Neuron; 2019 Sep; 103(5):820-835.e7. PubMed ID: 31301936
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The age-related microglial transformation in Alzheimer's disease pathogenesis.
    Yuan C; Aierken A; Xie Z; Li N; Zhao J; Qing H
    Neurobiol Aging; 2020 Aug; 92():82-91. PubMed ID: 32408056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced TREM2 activation in microglia of patients with Alzheimer's disease.
    Okuzono Y; Sakuma H; Miyakawa S; Ifuku M; Lee J; Das D; Banerjee A; Zhao Y; Yamamoto K; Ando T; Sato S
    FEBS Open Bio; 2021 Nov; 11(11):3063-3080. PubMed ID: 34523252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
    Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
    J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
    [No Abstract]   [Full Text] [Related]  

  • 13. TREM2-induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology.
    Fracassi A; Marcatti M; Tumurbaatar B; Woltjer R; Moreno S; Taglialatela G
    Brain Pathol; 2023 Jan; 33(1):e13108. PubMed ID: 35816404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease.
    Jiang T; Tan L; Zhu XC; Zhang QQ; Cao L; Tan MS; Gu LZ; Wang HF; Ding ZZ; Zhang YD; Yu JT
    Neuropsychopharmacology; 2014 Dec; 39(13):2949-62. PubMed ID: 25047746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2).
    Zhong L; Wang Z; Wang D; Wang Z; Martens YA; Wu L; Xu Y; Wang K; Li J; Huang R; Can D; Xu H; Bu G; Chen XF
    Mol Neurodegener; 2018 Mar; 13(1):15. PubMed ID: 29587871
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Established Beta Amyloid Pathology Is Unaffected by TREM2 Elevation in Reactive Microglia in an Alzheimer's Disease Mouse Model.
    Yuan Q; Liu X; Zhang Y; Xian YF; Zou J; Zhang X; Huang P; Song YQ; Lin ZX
    Molecules; 2021 May; 26(9):. PubMed ID: 34064330
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
    Wang Y; Ulland TK; Ulrich JD; Song W; Tzaferis JA; Hole JT; Yuan P; Mahan TE; Shi Y; Gilfillan S; Cella M; Grutzendler J; DeMattos RB; Cirrito JR; Holtzman DM; Colonna M
    J Exp Med; 2016 May; 213(5):667-75. PubMed ID: 27091843
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The relationship between the morphological subtypes of microglia and Alzheimer's disease neuropathology.
    Paasila PJ; Davies DS; Kril JJ; Goldsbury C; Sutherland GT
    Brain Pathol; 2019 Nov; 29(6):726-740. PubMed ID: 30803086
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TREM2, microglia, and Alzheimer's disease.
    Qin Q; Teng Z; Liu C; Li Q; Yin Y; Tang Y
    Mech Ageing Dev; 2021 Apr; 195():111438. PubMed ID: 33516818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation.
    Zhou J; Yu W; Zhang M; Tian X; Li Y; Lü Y
    Neurochem Res; 2019 May; 44(5):1138-1151. PubMed ID: 30756214
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.