239 related articles for article (PubMed ID: 36966244)
21. Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study.
Morenas-Rodríguez E; Li Y; Nuscher B; Franzmeier N; Xiong C; Suárez-Calvet M; Fagan AM; Schultz S; Gordon BA; Benzinger TLS; Hassenstab J; McDade E; Feederle R; Karch CM; Schlepckow K; Morris JC; Kleinberger G; Nellgard B; Vöglein J; Blennow K; Zetterberg H; Ewers M; Jucker M; Levin J; Bateman RJ; Haass C;
Lancet Neurol; 2022 Apr; 21(4):329-341. PubMed ID: 35305339
[TBL] [Abstract][Full Text] [Related]
22. Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation.
Zheng H; Liu CC; Atagi Y; Chen XF; Jia L; Yang L; He W; Zhang X; Kang SS; Rosenberry TL; Fryer JD; Zhang YW; Xu H; Bu G
Neurobiol Aging; 2016 Jun; 42():132-41. PubMed ID: 27143430
[TBL] [Abstract][Full Text] [Related]
23. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Zhou Y; Song WM; Andhey PS; Swain A; Levy T; Miller KR; Poliani PL; Cominelli M; Grover S; Gilfillan S; Cella M; Ulland TK; Zaitsev K; Miyashita A; Ikeuchi T; Sainouchi M; Kakita A; Bennett DA; Schneider JA; Nichols MR; Beausoleil SA; Ulrich JD; Holtzman DM; Artyomov MN; Colonna M
Nat Med; 2020 Jan; 26(1):131-142. PubMed ID: 31932797
[TBL] [Abstract][Full Text] [Related]
24. TREM2 dependent and independent functions of microglia in Alzheimer's disease.
Hou J; Chen Y; Grajales-Reyes G; Colonna M
Mol Neurodegener; 2022 Dec; 17(1):84. PubMed ID: 36564824
[TBL] [Abstract][Full Text] [Related]
25. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
Zhong L; Xu Y; Zhuo R; Wang T; Wang K; Huang R; Wang D; Gao Y; Zhu Y; Sheng X; Chen K; Wang N; Zhu L; Can D; Marten Y; Shinohara M; Liu CC; Du D; Sun H; Wen L; Xu H; Bu G; Chen XF
Nat Commun; 2019 Mar; 10(1):1365. PubMed ID: 30911003
[TBL] [Abstract][Full Text] [Related]
26. Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
McQuade A; Kang YJ; Hasselmann J; Jairaman A; Sotelo A; Coburn M; Shabestari SK; Chadarevian JP; Fote G; Tu CH; Danhash E; Silva J; Martinez E; Cotman C; Prieto GA; Thompson LM; Steffan JS; Smith I; Davtyan H; Cahalan M; Cho H; Blurton-Jones M
Nat Commun; 2020 Oct; 11(1):5370. PubMed ID: 33097708
[TBL] [Abstract][Full Text] [Related]
27. Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
Zhao N; Qiao W; Li F; Ren Y; Zheng J; Martens YA; Wang X; Li L; Liu CC; Chen K; Zhu Y; Ikezu TC; Li Z; Meneses AD; Jin Y; Knight JA; Chen Y; Bastea L; Linares C; Sonustun B; Job L; Smith ML; Xie M; Liu YU; Umpierre AD; Haruwaka K; Quicksall ZS; Storz P; Asmann YW; Wu LJ; Bu G
J Exp Med; 2022 Dec; 219(12):. PubMed ID: 36107206
[TBL] [Abstract][Full Text] [Related]
28. TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices.
Lue LF; Schmitz CT; Serrano G; Sue LI; Beach TG; Walker DG
Brain Pathol; 2015 Jul; 25(4):469-80. PubMed ID: 25186950
[TBL] [Abstract][Full Text] [Related]
29. Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer's Disease.
Basha SC; Ramaiah MJ; Kosagisharaf JR
J Alzheimers Dis; 2023; 94(s1):S319-S333. PubMed ID: 36683512
[TBL] [Abstract][Full Text] [Related]
30. TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice.
Jiang T; Wan Y; Zhang YD; Zhou JS; Gao Q; Zhu XC; Shi JQ; Lu H; Tan L; Yu JT
Mol Neurobiol; 2017 Mar; 54(2):855-865. PubMed ID: 26780455
[TBL] [Abstract][Full Text] [Related]
31. Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
Delizannis AT; Nonneman A; Tsering W; De Bondt A; Van den Wyngaert I; Zhang B; Meymand E; Olufemi MF; Koivula P; Maimaiti S; Trojanowski JQ; Lee VM; Brunden KR
Acta Neuropathol Commun; 2021 Sep; 9(1):150. PubMed ID: 34503586
[TBL] [Abstract][Full Text] [Related]
32. TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Ulland TK; Song WM; Huang SC; Ulrich JD; Sergushichev A; Beatty WL; Loboda AA; Zhou Y; Cairns NJ; Kambal A; Loginicheva E; Gilfillan S; Cella M; Virgin HW; Unanue ER; Wang Y; Artyomov MN; Holtzman DM; Colonna M
Cell; 2017 Aug; 170(4):649-663.e13. PubMed ID: 28802038
[TBL] [Abstract][Full Text] [Related]
33. TREM2 signalling as a multifaceted player in brain homoeostasis and a potential target for Alzheimer's disease treatment.
Ayyubova G
Eur J Neurosci; 2023 Feb; 57(4):718-733. PubMed ID: 36637116
[TBL] [Abstract][Full Text] [Related]
34. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Martiskainen H; Viswanathan J; Nykänen NP; Kurki M; Helisalmi S; Natunen T; Sarajärvi T; Kurkinen KM; Pursiheimo JP; Rauramaa T; Alafuzoff I; Jääskeläinen JE; Leinonen V; Soininen H; Haapasalo A; Huttunen HJ; Hiltunen M
Neurobiol Aging; 2015 Feb; 36(2):1221.e15-28. PubMed ID: 25281018
[TBL] [Abstract][Full Text] [Related]
35. Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology.
Suárez-Calvet M; Morenas-Rodríguez E; Kleinberger G; Schlepckow K; Araque Caballero MÁ; Franzmeier N; Capell A; Fellerer K; Nuscher B; Eren E; Levin J; Deming Y; Piccio L; Karch CM; Cruchaga C; Shaw LM; Trojanowski JQ; Weiner M; Ewers M; Haass C;
Mol Neurodegener; 2019 Jan; 14(1):1. PubMed ID: 30630532
[TBL] [Abstract][Full Text] [Related]
36. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
Lee CYD; Daggett A; Gu X; Jiang LL; Langfelder P; Li X; Wang N; Zhao Y; Park CS; Cooper Y; Ferando I; Mody I; Coppola G; Xu H; Yang XW
Neuron; 2018 Mar; 97(5):1032-1048.e5. PubMed ID: 29518357
[TBL] [Abstract][Full Text] [Related]
37. Role of TREM2 in Alzheimer's Disease: A Long Road Ahead.
Kulkarni B; Kumar D; Cruz-Martins N; Sellamuthu S
Mol Neurobiol; 2021 Oct; 58(10):5239-5252. PubMed ID: 34275100
[TBL] [Abstract][Full Text] [Related]
38. Microglial TREM2 at the Intersection of Brain Aging and Alzheimer's Disease.
Qu W; Li L
Neuroscientist; 2023 Jun; 29(3):302-316. PubMed ID: 34470515
[TBL] [Abstract][Full Text] [Related]
39. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
von Saucken VE; Jay TR; Landreth GE
Neurobiol Dis; 2020 Nov; 145():105072. PubMed ID: 32890775
[TBL] [Abstract][Full Text] [Related]
40. TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice.
Jiang T; Zhang YD; Chen Q; Gao Q; Zhu XC; Zhou JS; Shi JQ; Lu H; Tan L; Yu JT
Neuropharmacology; 2016 Jun; 105():196-206. PubMed ID: 26802771
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
