BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 36971790)

  • 1. Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis.
    Flora GD; Nayak MK; Ghatge M; Kumskova M; Patel RB; Chauhan AK
    Blood Adv; 2023 Jun; 7(11):2347-2359. PubMed ID: 36971790
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial calcium uniporter b deletion inhibits platelet function and reduces susceptibility to arterial thrombosis.
    Ghatge M; Nayak MK; Flora GD; Kumskova M; Jain A; Patel RB; Lin Z; Usachev YM; Chauhan AK
    J Thromb Haemost; 2023 Aug; 21(8):2163-2174. PubMed ID: 37061131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis.
    Nayak MK; Dhanesha N; Doddapattar P; Rodriguez O; Sonkar VK; Dayal S; Chauhan AK
    Blood Adv; 2018 Aug; 2(15):2029-2038. PubMed ID: 30108111
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
    Qiao J; Wu X; Luo Q; Wei G; Xu M; Wu Y; Liu Y; Li X; Zi J; Ju W; Fu L; Chen C; Wu Q; Zhu S; Qi K; Li D; Li Z; Andrews RK; Zeng L; Gardiner EE; Xu K
    Haematologica; 2018 Sep; 103(9):1568-1576. PubMed ID: 29794149
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
    Jha MK; Song GJ; Lee MG; Jeoung NH; Go Y; Harris RA; Park DH; Kook H; Lee IK; Suk K
    J Neurosci; 2015 Oct; 35(42):14353-69. PubMed ID: 26490872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DCA Protects against Oxidation Injury Attributed to Cerebral Ischemia-Reperfusion by Regulating Glycolysis through PDK2-PDH-Nrf2 Axis.
    Zhao X; Li S; Mo Y; Li R; Huang S; Zhang A; Ni X; Dai Q; Wang J
    Oxid Med Cell Longev; 2021; 2021():5173035. PubMed ID: 34712383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation.
    Dunford EC; Herbst EA; Jeoung NH; Gittings W; Inglis JG; Vandenboom R; LeBlanc PJ; Harris RA; Peters SJ
    Am J Physiol Regul Integr Comp Physiol; 2011 Jun; 300(6):R1487-93. PubMed ID: 21411764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis.
    Nayak MK; Ghatge M; Flora GD; Dhanesha N; Jain M; Markan KR; Potthoff MJ; Lentz SR; Chauhan AK
    Blood; 2021 Mar; 137(12):1658-1668. PubMed ID: 33027814
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.
    Rahman MH; Jha MK; Kim JH; Nam Y; Lee MG; Go Y; Harris RA; Park DH; Kook H; Lee IK; Suk K
    J Biol Chem; 2016 Mar; 291(11):6011-6025. PubMed ID: 26769971
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic targeting of platelets to combat thrombosis: dawn of a new paradigm?
    Flora GD; Nayak MK; Ghatge M; Chauhan AK
    Cardiovasc Res; 2023 Nov; 119(15):2497-2507. PubMed ID: 37706546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes.
    Tao R; Xiong X; Harris RA; White MF; Dong XC
    PLoS One; 2013; 8(8):e71997. PubMed ID: 23940800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer.
    Nunes-Xavier CE; Mingo J; Emaldi M; Flem-Karlsen K; Mælandsmo GM; Fodstad Ø; Llarena R; López JI; Pulido R
    Front Oncol; 2022; 12():873516. PubMed ID: 35692804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice.
    Niki M; Nayak MK; Jin H; Bhasin N; Plow EF; Pandolfi PP; Rothman PB; Chauhan AK; Lentz SR
    Thromb Haemost; 2016 May; 115(5):969-78. PubMed ID: 26790499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Real-time hyperpolarized
    Sharma G; Wu CY; Wynn RM; Gui W; Malloy CR; Sherry AD; Chuang DT; Khemtong C
    Sci Rep; 2019 Nov; 9(1):16480. PubMed ID: 31712597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells.
    Du J; Li Q; Tang F; Puchowitz MA; Fujioka H; Dunwoodie SL; Danielpour D; Yang YC
    Stem Cells Dev; 2014 Jan; 23(2):83-94. PubMed ID: 24083546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.
    Gopal K; Saleme B; Al Batran R; Aburasayn H; Eshreif A; Ho KL; Ma WK; Almutairi M; Eaton F; Gandhi M; Park EA; Sutendra G; Ussher JR
    Am J Physiol Heart Circ Physiol; 2017 Sep; 313(3):H479-H490. PubMed ID: 28687587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone.
    Holness MJ; Bulmer K; Smith ND; Sugden MC
    Biochem J; 2003 Feb; 369(Pt 3):687-95. PubMed ID: 12435272
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype.
    Min BK; Park S; Kang HJ; Kim DW; Ham HJ; Ha CM; Choi BJ; Lee JY; Oh CJ; Yoo EK; Kim HE; Kim BG; Jeon JH; Hyeon DY; Hwang D; Kim YH; Lee CH; Lee T; Kim JW; Choi YK; Park KG; Chawla A; Lee J; Harris RA; Lee IK
    Front Immunol; 2019; 10():944. PubMed ID: 31134063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PDK2-enhanced glycolysis promotes fibroblast proliferation in thyroid-associated ophthalmopathy.
    Ma R; Gan L; Ren H; Harrison A; Qian J
    J Mol Endocrinol; 2020 Nov; 65(4):163-174. PubMed ID: 33086191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Migfilin supports hemostasis and thrombosis through regulating platelet αIIbβ3 outside-in signaling.
    Zhou Y; Hu M; Chen X; Wang S; Li J; Sa L; Li L; Huang J; Cheng H; Hu H
    Haematologica; 2020 Nov; 105(11):2608-2618. PubMed ID: 33131250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.