164 related articles for article (PubMed ID: 36976494)
1. Glioma Cells Expressing High Levels of ALDH5A1 Exhibit Enhanced Migration Transcriptional Signature in Patient Tumors.
Piperi C; Saurty-Seerunghen MS; Levidou G; Sepsa A; Trigka EA; Klonou A; Markouli M; Strepkos D; Spyropoulou A; Kanakoglou DS; Lakiotaki E; Karatrasoglou EA; Boviatsis E; El-Habr EA; Korkolopoulou P
Neurotherapeutics; 2023 Apr; 20(3):881-895. PubMed ID: 36976494
[TBL] [Abstract][Full Text] [Related]
2. GABA, glutamine, glutamate oxidation and succinic semialdehyde dehydrogenase expression in human gliomas.
Hujber Z; Horváth G; Petővári G; Krencz I; Dankó T; Mészáros K; Rajnai H; Szoboszlai N; Leenders WPJ; Jeney A; Tretter L; Sebestyén A
J Exp Clin Cancer Res; 2018 Nov; 37(1):271. PubMed ID: 30404651
[TBL] [Abstract][Full Text] [Related]
3. Clinical diagnosis and mutation analysis of four Chinese families with succinic semialdehyde dehydrogenase deficiency.
Wang P; Cai F; Cao L; Wang Y; Zou Q; Zhao P; Wang C; Zhang Y; Cai C; Shu J
BMC Med Genet; 2019 May; 20(1):88. PubMed ID: 31117962
[TBL] [Abstract][Full Text] [Related]
4. A Missense Variant in
Vernau KM; Struys E; Letko A; Woolard KD; Aguilar M; Brown EA; Cissell DD; Dickinson PJ; Shelton GD; Broome MR; Gibson KM; Pearl PL; König F; Van Winkle TJ; O'Brien D; Roos B; Matiasek K; Jagannathan V; Drögemüller C; Mansour TA; Brown CT; Bannasch DL
Genes (Basel); 2020 Sep; 11(9):. PubMed ID: 32887425
[TBL] [Abstract][Full Text] [Related]
5. Temporal metabolomics in dried bloodspots suggests multipathway disruptions in aldh5a1
Brown M; Turgeon C; Rinaldo P; Roullet JB; Gibson KM
Mol Genet Metab; 2019 Dec; 128(4):397-408. PubMed ID: 31699650
[TBL] [Abstract][Full Text] [Related]
6. A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma.
El-Habr EA; Dubois LG; Burel-Vandenbos F; Bogeas A; Lipecka J; Turchi L; Lejeune FX; Coehlo PL; Yamaki T; Wittmann BM; Fareh M; Mahfoudhi E; Janin M; Narayanan A; Morvan-Dubois G; Schmitt C; Verreault M; Oliver L; Sharif A; Pallud J; Devaux B; Puget S; Korkolopoulou P; Varlet P; Ottolenghi C; Plo I; Moura-Neto V; Virolle T; Chneiweiss H; Junier MP
Acta Neuropathol; 2017 Apr; 133(4):645-660. PubMed ID: 28032215
[TBL] [Abstract][Full Text] [Related]
7. Succinic semialdehyde dehydrogenase deficiency: The combination of a novel ALDH5A1 gene mutation and a missense SNP strongly affects SSADH enzyme activity and stability.
Menduti G; Biamino E; Vittorini R; Vesco S; Puccinelli MP; Porta F; Capo C; Leo S; Ciminelli BM; Iacovelli F; Spada M; Falconi M; Malaspina P; Rossi L
Mol Genet Metab; 2018 Jul; 124(3):210-215. PubMed ID: 29895405
[TBL] [Abstract][Full Text] [Related]
8. Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency.
Malaspina P; Picklo MJ; Jakobs C; Snead OC; Gibson KM
Hum Genomics; 2009 Jan; 3(2):106-20. PubMed ID: 19164088
[TBL] [Abstract][Full Text] [Related]
9. Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development.
Jansen EE; Struys E; Jakobs C; Hager E; Snead OC; Gibson KM
BMC Dev Biol; 2008 Nov; 8():112. PubMed ID: 19040727
[TBL] [Abstract][Full Text] [Related]
10. Functional analysis of thirty-four suspected pathogenic missense variants in ALDH5A1 gene associated with succinic semialdehyde dehydrogenase deficiency.
Pop A; Smith DEC; Kirby T; Walters D; Gibson KM; Mahmoudi S; van Dooren SJM; Kanhai WA; Fernandez-Ojeda MR; Wever EJM; Koster J; Waterham HR; Grob B; Roos B; Wamelink MMC; Chen J; Natesan S; Salomons GS
Mol Genet Metab; 2020 Jul; 130(3):172-178. PubMed ID: 32402538
[TBL] [Abstract][Full Text] [Related]
11. SSADH Variants Increase Susceptibility of U87 Cells to Mitochondrial Pro-Oxidant Insult.
Menduti G; Vitaliti A; Capo CR; Lettieri-Barbato D; Aquilano K; Malaspina P; Rossi L
Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32575506
[TBL] [Abstract][Full Text] [Related]
12. Mutation analysis and prenatal diagnosis in a Chinese family with succinic semialdehyde dehydrogenase and a systematic review of the literature of reported ALDH5A1 mutations.
Liu N; Kong XD; Kan QC; Shi HR; Wu QH; Zhuo ZH; Bai QL; Jiang M
J Perinat Med; 2016 May; 44(4):441-51. PubMed ID: 25431891
[TBL] [Abstract][Full Text] [Related]
13. SSADH deficiency in an Italian family: a novel ALDH5A1 gene mutation affecting the succinic semialdehyde substrate binding site.
Leo S; Capo C; Ciminelli BM; Iacovelli F; Menduti G; Funghini S; Donati MA; Falconi M; Rossi L; Malaspina P
Metab Brain Dis; 2017 Oct; 32(5):1383-1388. PubMed ID: 28664505
[TBL] [Abstract][Full Text] [Related]
14. ALDH5A1 acts as a tumour promoter and has a prognostic impact in papillary thyroid carcinoma.
Deng XY; Gan XX; Feng JH; Cai WS; Wang XQ; Shen L; Luo HT; Chen Z; Guo M; Cao J; Shen F; Xu B
Cell Biochem Funct; 2021 Mar; 39(2):317-325. PubMed ID: 32881051
[TBL] [Abstract][Full Text] [Related]
15. Human iPSC-derived neural stem cells with ALDH5A1 mutation as a model of succinic semialdehyde dehydrogenase deficiency.
Chen X; Peng M; Cai Y; Zhou C; Liu L
BMC Neurosci; 2022 Dec; 23(1):77. PubMed ID: 36527006
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (gamma-hydroxybutyric aciduria). Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/- mice and characterization of gamma-hydroxybutyric acid pharmacology.
Knerr I; Pearl PL; Bottiglieri T; Snead OC; Jakobs C; Gibson KM
J Inherit Metab Dis; 2007 Jun; 30(3):279-94. PubMed ID: 17457693
[TBL] [Abstract][Full Text] [Related]
17. The effects of a ketogenic diet on ATP concentrations and the number of hippocampal mitochondria in Aldh5a1(-/-) mice.
Nylen K; Velazquez JL; Sayed V; Gibson KM; Burnham WM; Snead OC
Biochim Biophys Acta; 2009 Mar; 1790(3):208-12. PubMed ID: 19168117
[TBL] [Abstract][Full Text] [Related]
18. Candidate gene analysis of the succinic semialdehyde dehydrogenase gene (ALDH5A1) in patients with idiopathic generalized epilepsy and photosensitivity.
Lorenz S; Heils A; Taylor KP; Gehrmann A; Muhle H; Gresch M; Becker T; Tauer U; Stephani U; Sander T
Neurosci Lett; 2006 Apr; 397(3):234-9. PubMed ID: 16406321
[TBL] [Abstract][Full Text] [Related]
19. Familial 6p22.2 duplication associates with mild developmental delay and increased SSADH activity.
Siggberg L; Mustonen A; Schuit R; Salomons GS; Roos B; Gibson KM; Jakobs C; Ignatius J; Knuutila S
Am J Med Genet B Neuropsychiatr Genet; 2011 Jun; 156B(4):448-53. PubMed ID: 21438145
[TBL] [Abstract][Full Text] [Related]
20. Decreased expression of ALDH5A1 predicts prognosis in patients with ovarian cancer.
Tian X; Han Y; Yu L; Luo B; Hu Z; Li X; Yang Z; Wang X; Huang W; Wang H; Zhang Q; Ma D
Cancer Biol Ther; 2017 Apr; 18(4):245-251. PubMed ID: 28346042
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
