BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 36982238)

  • 1. PTB Regulates the Metabolic Pathways and Cell Function of Keloid Fibroblasts through Alternative Splicing of PKM.
    Huang R; Han R; Yan Y; Yang J; Dong G; Wang M; Su Z; Jiao H; Fan J
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer.
    David CJ; Chen M; Assanah M; Canoll P; Manley JL
    Nature; 2010 Jan; 463(7279):364-8. PubMed ID: 20010808
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Altered glucose metabolism and cell function in keloid fibroblasts under hypoxia.
    Wang Q; Wang P; Qin Z; Yang X; Pan B; Nie F; Bi H
    Redox Biol; 2021 Jan; 38():101815. PubMed ID: 33278780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer.
    Yadav S; Bhagat SD; Gupta A; Samaiya A; Srivastava A; Shukla S
    BMC Cancer; 2019 Nov; 19(1):1031. PubMed ID: 31675998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic reprogramming in keloid fibroblasts: Aerobic glycolysis and a novel therapeutic strategy.
    Li Q; Qin Z; Nie F; Bi H; Zhao R; Pan B; Ma J; Xie X
    Biochem Biophys Res Commun; 2018 Feb; 496(2):641-647. PubMed ID: 29337061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the Glycolytic Enzyme PGK1 to Inhibit the Warburg Effect: A New Strategy for Keloid Therapy.
    Wang P; Wang Q; Yang X; An Y; Wang J; Nie F; Pan B; Bi H; Qin Z
    Plast Reconstr Surg; 2023 Jun; 151(6):970e-980e. PubMed ID: 36728674
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B; Whitaker-Menezes D; Martinez-Outschoorn UE; Witkiewicz AK; Birbe R; Howell A; Pestell RG; Smith J; Daniel R; Sotgia F; Lisanti MP
    Cancer Biol Ther; 2011 Dec; 12(12):1101-13. PubMed ID: 22236875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.
    Su CH; Hung KY; Hung SC; Tarn WY
    Mol Cell Biol; 2017 Feb; 37(3):. PubMed ID: 27821480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progression.
    Zhao H; Jiang R; Feng Z; Wang X; Zhang C
    J Transl Med; 2023 Nov; 21(1):833. PubMed ID: 37980488
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.
    Caruso P; Dunmore BJ; Schlosser K; Schoors S; Dos Santos C; Perez-Iratxeta C; Lavoie JR; Zhang H; Long L; Flockton AR; Frid MG; Upton PD; D'Alessandro A; Hadinnapola C; Kiskin FN; Taha M; Hurst LA; Ormiston ML; Hata A; Stenmark KR; Carmeliet P; Stewart DJ; Morrell NW
    Circulation; 2017 Dec; 136(25):2451-2467. PubMed ID: 28971999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TGF-β1 Induces Polypyrimidine Tract-Binding Protein to Alter Fibroblasts Proliferation and Fibronectin Deposition in Keloid.
    Jiao H; Dong P; Yan L; Yang Z; Lv X; Li Q; Zong X; Fan J; Fu X; Liu X; Xiao R
    Sci Rep; 2016 Nov; 6():38033. PubMed ID: 27897224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.
    Chen M; Zhang J; Manley JL
    Cancer Res; 2010 Nov; 70(22):8977-80. PubMed ID: 20978194
    [TBL] [Abstract][Full Text] [Related]  

  • 14. No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.
    Bluemlein K; Grüning NM; Feichtinger RG; Lehrach H; Kofler B; Ralser M
    Oncotarget; 2011 May; 2(5):393-400. PubMed ID: 21789790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.
    Gu Z; Xia J; Xu H; Frech I; Tricot G; Zhan F
    J Hematol Oncol; 2017 Jan; 10(1):17. PubMed ID: 28086949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
    Lin J; Wu S; Shen Q; Liu J; Huang S; Peng G; Qiao Y
    Cell Prolif; 2021 Aug; 54(8):e13096. PubMed ID: 34240779
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Estradiol-17β upregulates pyruvate kinase M2 expression to coactivate estrogen receptor-α and to integrate metabolic reprogramming with the mitogenic response in endometrial cells.
    Salama SA; Mohammad MA; Diaz-Arrastia CR; Kamel MW; Kilic GS; Ndofor BT; Abdel-Baki MS; Theiler SK
    J Clin Endocrinol Metab; 2014 Oct; 99(10):3790-9. PubMed ID: 24471565
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SRSF3, a Splicer of the PKM Gene, Regulates Cell Growth and Maintenance of Cancer-Specific Energy Metabolism in Colon Cancer Cells.
    Kuranaga Y; Sugito N; Shinohara H; Tsujino T; Taniguchi K; Komura K; Ito Y; Soga T; Akao Y
    Int J Mol Sci; 2018 Oct; 19(10):. PubMed ID: 30279379
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The emerging role of PKM in keratinocyte homeostasis and pathophysiology.
    Demeter JB; Elshaarrawi A; Dowker-Key PD; Bettaieb A
    FEBS J; 2023 May; 290(9):2311-2319. PubMed ID: 36541050
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sam68 promotes aerobic glycolysis in colorectal cancer by regulating PKM2 alternative splicing.
    Zhao J; Li J; Hassan W; Xu D; Wang X; Huang Z
    Ann Transl Med; 2020 Apr; 8(7):459. PubMed ID: 32395503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.